Date published: 2025-9-11

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Menin 抗体 (E-9): sc-390345

5.0(3)
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说明书
  • Menin抗体(E-9)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Menin的N-terminus的氨基酸3-21之间
  • 推荐用于 mouse, rat 和 human 来源的Menin WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Menin 抗体 (E-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Menin 抗体 (E-9) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Menin(多发性内分泌腺瘤I、MEN1、MEAI、SCG2)是一种核肿瘤抑制因子,在多发性内分泌腺瘤I型(MEN1)患者中会发生突变。Menin可以通过共价组蛋白修饰来激活分化调节基因的转录。在成骨细胞中,menin与TGFβeta/Smad3通路的相互作用会负向调节BMP2/Smad1/5和Runx2依赖的转录活性,从而抑制晚期分化。Menin通过影响IGFBP-2启动子来调节IGFBP-2的表达。通过腺病毒异位过表达menin可以以一种Bax/Bak依赖的方式诱导小鼠胚胎成纤维细胞凋亡。存在两种mRNA,其中较短的mRNA有两种变体,这些变体通过可变剪接改变CDS。已经发现了五个在5'UTR区域发生可变剪接的变体。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Menin 抗体 (E-9)

sc-390345
200 µg/ml
RMB2377.00

Menin (E-9): m-IgG Fc BP-HRP 套装

sc-540787
200 µg Ab; 10 µg BP
RMB2662.00

Menin (E-9): m-IgG1 BP-HRP 套装

sc-542370
200 µg Ab; 20 µg BP
RMB2662.00

Menin (E-9) 中和勝肽

sc-390345 P
100 µg/0.5 ml
RMB511.00

quel isoforme de la menin est reconnu par cet anticorps merci

Asked by: chaima
merci pour votre question. Cet anticorps a été généré contre les acides aminés 3-21 en N-terminal de la protéine Menin d'origine humaine. Il devrait donc reconnaitre tous les isoformes de cette protéine, la partie N-terminale utilisée pour générer cet anticorps étant présente dans les 3 isoformes. thank you for your question regarding the isoforms detected by this antibody. This antibody has been raised against the amino acids 3-21 at the N-terminus of Menin of human origin. It should therefore detects all the isoforms.
Answered by: Tech Support Europe
Date published: 2019-12-11

What application is the blocking peptide sc-390345 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Positive western blot band in JurkatWe used this antibody for expression detection of Menin by western blot. We got a very nice band around the correct molecular weight in Jurkat cells.
Date published: 2017-02-08
Rated 5 out of 5 by from Exceptional immunoperoxidase nuclear andExceptional immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human testis tissue. -SCBT QC
Date published: 2015-05-21
Rated 5 out of 5 by from Nice Western Blot data of Menin expression in KNice Western Blot data of Menin expression in K-562, Jurkat and A-431 nuclear extracts. -SCBT QC
Date published: 2014-03-29
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Menin 抗体 (E-9) is rated 5.0 out of 5 by 3.
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