Date published: 2025-9-7

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MAVS 抗体 (E-6): sc-365334

4.6(7)
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说明书
  • MAVS抗体(E-6)是小鼠单克隆IgG1 κ, 在13篇文献中引用,规格为200 µg/ml
  • 针对氨基酸1-300的抗原,在mouse起源的MAVS的N-terminal细胞质域内
  • MAVS 抗体 (E-6) 推荐用于WB, IP, IF 和 ELISA,检测mouse 来源的 MAVS
  • 抗MAVS抗体(E-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取MAVS (E-6): sc-365334免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是MAVS Antibody (E-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与MAVS Antibody (E-6) 打包提供(请参阅下面的订购信息)。

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関連項目

MAVS抗体(E-6)是一种IgG1κ小鼠单克隆MAVS抗体,可通过WB、IP、IF和ELISA检测小鼠来源的MAVS。MAVS抗体(E-6)有非偶联抗MAVS抗体形式和多种偶联形式的抗MAVS抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。MAVS(线粒体抗病毒信号蛋白),也称为IPS1、KIAA1271、VISA或CARDIF,是一种540个氨基酸的蛋白质,含有一个CARD结构域和几个跨膜结构域,定位于线粒体外膜。MAVS在全身表达,在肝脏、心脏、胎盘、骨骼肌和外周血白细胞中表达最高,在检测双链(ds)病毒复制的蛋白质(如RIG-I)下游发挥作用,是针对ds病毒感染的适当免疫反应所必需的。MAVS被认为可以激活导致抗病毒细胞因子诱导的途径,并可能保护细胞免受病毒诱导的凋亡。 MAVS功能可以通过蛋白酶复合物切割而失活,所述蛋白酶复合物降解CARD和跨膜结构域,从而阻止MAVS与其他蛋白质相互作用。由于选择性剪接事件,表达了三种MAVS同工型。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

MAVS 抗体 (E-6)

sc-365334
200 µg/ml
RMB2377.00

MAVS (E-6): m-IgG Fc BP-HRP 套装

sc-529353
200 µg Ab; 10 µg BP
RMB2662.00

MAVS (E-6): m-IgGκ BP-HRP 套装

sc-522211
200 µg Ab, 40 µg BP
RMB2662.00

MAVS (E-6): m-IgG1 BP-HRP 套装

sc-543474
200 µg Ab; 20 µg BP
RMB2662.00

MAVS 抗体 (E-6) AC

sc-365334 AC
500 µg/ml, 25% agarose
RMB3129.00

MAVS 抗体 (E-6) HRP

sc-365334 HRP
200 µg/ml
RMB2377.00

MAVS 抗体 (E-6) FITC

sc-365334 FITC
200 µg/ml
RMB2482.00

MAVS 抗体 (E-6) PE

sc-365334 PE
200 µg/ml
RMB2580.00

MAVS 抗体 (E-6) Alexa Fluor® 488

sc-365334 AF488
200 µg/ml
RMB2685.00

MAVS 抗体 (E-6) Alexa Fluor® 546

sc-365334 AF546
200 µg/ml
RMB2685.00

MAVS 抗体 (E-6) Alexa Fluor® 594

sc-365334 AF594
200 µg/ml
RMB2685.00

MAVS 抗体 (E-6) Alexa Fluor® 647

sc-365334 AF647
200 µg/ml
RMB2685.00

MAVS 抗体 (E-6) Alexa Fluor® 680

sc-365334 AF680
200 µg/ml
RMB2685.00

MAVS 抗体 (E-6) Alexa Fluor® 790

sc-365334 AF790
200 µg/ml
RMB2685.00

I had this frozen for an hour. Is the integrity still okay?

Asked by: LU1228
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2023-02-08

Does the MAVS Antibody (E-6): sc-365334 work in BMDMs and MEFs for IF staining? I tried to do IF staining on BMDMs but failed. Any protocol which may work nice?

Asked by: asdzxcx
Thank you for your question. We do not currently have any data in those specific types of mouse cells. However, the antibody is recommended for IF in mouse samples, and we do have data and citations available using this antibody in mouse for this application. Please contact our Technical Service Department for assistance in troubleshooting the antibody.
Answered by: Technical Support
Date published: 2019-05-03

Can MAVS (E-6): sc-365334 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, MAVS (E-6): sc-365334 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Great antibody for IPWe tried this mouse antibody against MAVS for IP in mouse bone marrow derived macrophages, which works very well.
Date published: 2017-09-17
Rated 5 out of 5 by from strong band for WB analysisUsed for WB at a concentration of 1:1000 on mouse kidney extracts. The antibody gives strong band at the expected range of 54-75 kDa .
Date published: 2017-08-12
Rated 5 out of 5 by from Fine antibodyIt is a good antibody that detects endogenous MAVS in RAW264.7 cells.
Date published: 2017-03-15
Rated 5 out of 5 by from Great choice!This MAVS antibody shows beautiful fluorescent staining with methanol fixed cells.
Date published: 2017-01-31
Rated 5 out of 5 by from Produced great immunofluorescence cytoplasmicProduced great immunofluorescence cytoplasmic staining in methanol-fixed NIH/3T3 cells. -SCBT QC
Date published: 2015-05-02
Rated 3 out of 5 by from Works for IP does not work for WBWorks for IP does not work for WB
Date published: 2015-03-26
Rated 5 out of 5 by from Produced positive Western Blot data of MAVSProduced positive Western Blot data of MAVS expression in non-transfected and mouse MAVS transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-09-10
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MAVS 抗体 (E-6) is rated 4.6 out of 5 by 7.
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