Date published: 2025-9-8

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MAS1 抗体 (G-1): sc-390453

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说明书
  • MAS1 抗体 G-1 是小鼠单克隆 IgG1 κ,MAS1抗体, 在20篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-117位于human物种的MAS1的N-terminus
  • MAS1 抗体 (G-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 MAS1
  • 抗MAS1抗体(G-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取MAS1 (G-1): sc-390453免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 MAS1 抗体 (G-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与MAS1 抗体 (G-1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

MAS1抗体(G-1)是一种IgG1 κ小鼠单克隆MAS1抗体(也称为MAS1原癌基因抗体、G蛋白偶联受体抗体、原癌基因Mas抗体、MAS1癌基因抗体、MAS抗体、Mas相关G蛋白偶联受体A抗体或MGRA抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的MAS1蛋白。MAS1抗体(G-1)既可以是非偶联的抗MAS1抗体形式,也可以是多种偶联形式的抗MAS1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。原癌基因MAS1是位于质膜上的G蛋白偶联受体。在转染的NIH/3T3细胞中,MAS1具有弱的聚焦诱导活性。MAS1是血管紧张素II 1型(AT1)受体的拮抗剂,抑制血管紧张素II的作用。MAS1定位于小鼠心脏的心肌细胞。MAS1缺陷小鼠表现出较低的收缩张力和心率。MAS1的功能缺失可能会损害心脏的正常结构和功能。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

MAS1 抗体 (G-1) 参考文献:

  1. 小鼠 MAS 原癌基因的印记仅限于其反义 RNA。  |  Alenina, N., et al. 2002. Biochem Biophys Res Commun. 290: 1072-8. PMID: 11798184
  2. G 蛋白偶联受体 Mas 是血管紧张素 II 1 型受体的生理性颉颃物。  |  Kostenis, E., et al. 2005. Circulation. 111: 1806-13. PMID: 15809376
  3. 血管紧张肽-(1-7)通过激活 mas 受体抑制心肌细胞的生长。  |  Tallant, EA., et al. 2005. Am J Physiol Heart Circ Physiol. 289: H1560-6. PMID: 15951342
  4. 短期血管紧张素(1-7)受体 MAS 刺激可改善血压正常大鼠的内皮功能。  |  Faria-Silva, R., et al. 2005. Hypertension. 46: 948-52. PMID: 16087780
  5. 血管紧张素-(1-7)受体 Mas 与小鼠心脏中 AT1 和 AT2 受体功能性相互作用的证据。  |  Castro, CH., et al. 2005. Hypertension. 46: 937-42. PMID: 16157793
  6. 血管紧张肽-(1-7)受体 MAS 基因敲除小鼠体外和体内心脏功能的损害。  |  Santos, RA., et al. 2006. Hypertension. 47: 996-1002. PMID: 16567589
  7. MAS 原癌基因对血管紧张素 II 1 型受体的上调是由于 MAS 对 Gq/G11 的构成性激活。  |  Canals, M., et al. 2006. J Biol Chem. 281: 16757-67. PMID: 16611642
  8. Mas 原癌基因对血管紧张肽 II AT1 受体突变体缺陷的功能性挽救。  |  Santos, EL., et al. 2007. Regul Pept. 141: 159-67. PMID: 17320985
  9. CTLA-4功能不足的治疗方案。  |  Domińska, K. 2020. Int J Mol Sci. 21: PMID: 32604999
  10. ACE2/Ang-(1-7)/Mas1 轴与血管系统:对 COVID-19 相关血管疾病的血管保护。  |  Kuriakose, J., et al. 2021. Clin Sci (Lond). 135: 387-407. PMID: 33511992
  11. G 蛋白偶联受体 MAS1 对心肌梗死诱发的心肌损伤有抑制作用。  |  Zhou, G., et al. 2022. Int J Biol Macromol. 207: 72-80. PMID: 35247425
  12. 一种新的细胞癌基因的分离和特征描述,该基因编码一种具有多个潜在跨膜结构域的蛋白质。  |  Young, D., et al. 1986. Cell. 45: 711-9. PMID: 3708691

订购信息

产品名称产品编号规格价格数量收藏夹

MAS1 抗体 (G-1)

sc-390453
200 µg/ml
RMB2377.00

MAS1 (G-1): m-IgG Fc BP-HRP 套装

sc-530161
200 µg Ab; 10 µg BP
RMB2662.00

MAS1 (G-1): m-IgGκ BP-HRP 套装

sc-523538
200 µg Ab, 40 µg BP
RMB2662.00

MAS1 (G-1): m-IgG1 BP-HRP 套装

sc-543901
200 µg Ab; 20 µg BP
RMB2662.00

MAS1 抗体 (G-1) AC

sc-390453 AC
500 µg/ml, 25% agarose
RMB3129.00

MAS1 抗体 (G-1) HRP

sc-390453 HRP
200 µg/ml
RMB2377.00

MAS1 抗体 (G-1) FITC

sc-390453 FITC
200 µg/ml
RMB2482.00

MAS1 抗体 (G-1) PE

sc-390453 PE
200 µg/ml
RMB2580.00

MAS1 抗体 (G-1) Alexa Fluor® 488

sc-390453 AF488
200 µg/ml
RMB2685.00

MAS1 抗体 (G-1) Alexa Fluor® 546

sc-390453 AF546
200 µg/ml
RMB2685.00

MAS1 抗体 (G-1) Alexa Fluor® 594

sc-390453 AF594
200 µg/ml
RMB2685.00

MAS1 抗体 (G-1) Alexa Fluor® 647

sc-390453 AF647
200 µg/ml
RMB2685.00

MAS1 抗体 (G-1) Alexa Fluor® 680

sc-390453 AF680
200 µg/ml
RMB2685.00

MAS1 抗体 (G-1) Alexa Fluor® 790

sc-390453 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of equine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 14
Date published: 2017-02-10
  • y_2025, m_9, d_7, h_4CST
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Rated 5 out of 5 by from works wellIt works well and has strong band to my human recombinant MAS1 protein in WB.
Date published: 2017-06-07
Rated 5 out of 5 by from great specificityGot strong band at 1:500 in WB, very good signal !!!
Date published: 2017-05-18
Rated 5 out of 5 by from Strong detectionA great choice for detecting MAS1 in mouse, rat, or human. It will provide clear detection with strong signal. It has been used to publish.
Date published: 2017-01-27
Rated 5 out of 5 by from Exceptional immunoperoxidase cytoplasmicExceptional immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
Date published: 2015-03-07
Rated 5 out of 5 by from Nice Western Blot data of MAS1 expressionNice Western Blot data of MAS1 expression in mouse liver and rat liver tissue extracts and A549 whole cell lysate. -SCBT QC
Date published: 2013-06-14
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MAS1 抗体 (G-1) is rated 5.0 out of 5 by 5.
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