Date published: 2026-10-26

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MAP-2 Antibody (AA6) - Western Blotting - Image 353291
MAP-2 抗体 (AA6): sc-80013. IMR-32 全细胞裂解液 (A) 和人脑组织提取物 (B) 中 MAP-2 表达的 Western 印迹分析.
MAP-2 抗体 (AA6): sc-80013. IMR-32 全细胞裂解液 (A) 和人脑组织提取物 (B) 中 MAP-2 表达的 Western 印迹分析.

MAP-2 抗体 (AA6): sc-80013

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说明书
  • MAP-2抗体(AA6)是小鼠单克隆IgG2a κ, 在5篇文献中引用，规格为200 µg/ml
  • 针对rat来源的脑中稳定化的紫杉醇微管
  • 推荐用于 mouse, rat 和 human 来源的MAP-2 WB, IP 和 IF检测
  • 看 MAP-2 (A-4): sc-74421，可查看有标记的 MAP-2 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP是MAP-2 Antibody (AA6) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与MAP-2 Antibody (AA6) 搭配使用（请参阅下面的订购信息）。
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関連項目

附加MAP抗体，包括MAP-1B, MAP-2, MAP-4, MAP-6D1和MAP-1S

微管是细胞骨架网络的主要组成部分，与微管相关蛋白（MAP）相互作用。微管相关蛋白可分为结构和动态两类。结构微管相关蛋白包括MAP-1A、MAP-1B、MAP-2A、MAP-2B和MAP-2C，可刺激微管蛋白组装，增强微管稳定性，影响细胞内微管的空间分布。MAP-1和MAP-2均被认为是通过抑制微管的动态不稳定性来参与微管解聚的。MAP蛋白对微管动态不稳定的抑制被认为与MAP的磷酸化有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

MAP-2 抗体 (AA6) 参考文献:

  1. 小细胞肺癌细胞系中微管相关蛋白-2（MAP-2）的免疫细胞化学表达与神经元样突起。  |  Tanaka, K. and Terasaki, T. 2002. Jpn J Cancer Res. 93: 699-705. PMID: 12079519
  2. 饮食中的铝元素会选择性降低发育中和成年大鼠大脑中的MAP-2。  |  Johnson, GV., et al. 1992. Neurotoxicology. 13: 463-74. PMID: 1331920
  3. MAP-2与微管蛋白结合时，其蛋白水解降解的敏感性增加。  |  Grau, E., et al. 1992. Neurochem Res. 17: 967-71. PMID: 1508306
  4. 慢性脑供血不足大鼠海马中MAP-2、GAP-43和突触素蛋白的表达改变与认知障碍相关。  |  Liu, HX., et al. 2005. Brain Res Mol Brain Res. 139: 169-77. PMID: 15964096
  5. 运动技能训练可促进感觉运动恢复，并增加大鼠脑出血后运动皮层中微管相关蛋白-2（MAP-2）的免疫反应性。  |  Santos, MV., et al. 2013. ISRN Neurol. 2013: 159184. PMID: 23956876
  6. 抗200 kDa神经丝抗体与微管相关蛋白-2（MAP-2）发生交叉反应。  |  Allende, ML., et al. 1989. J Neurosci Res. 22: 130-3. PMID: 2468783
  7. 血管母细胞瘤表达 MAP 2：一项免疫组化研究及其对诊断的影响  |  Malafronte, PJ., et al. 2014. Pathology. 46: 450-1. PMID: 24977729
  8. 脑脊液中微管相关蛋白-2的抗体是神经精神系统性红斑狼疮的有效诊断生物标记物。  |  Yamada, Y., et al. 2016. Mod Rheumatol. 26: 562-8. PMID: 26667376
  9. 注射铵盐可诱导N-甲基-D-天冬氨酸受体介导的微管相关蛋白MAP-2的蛋白水解。  |  Felipo, V., et al. 1993. J Neurochem. 60: 1626-30. PMID: 8473887
  10. 创伤性脑损伤后大鼠海马MAP-2免疫染色中断。  |  Folkerts, MM., et al. 1998. J Neurotrauma. 15: 349-63. PMID: 9605349

订购信息

产品名称产品编号规格价格数量收藏夹

MAP-2 抗体 (AA6)

sc-80013
200 µg/ml
CNY2422.00

MAP-2 (AA6): m-IgG Fc BP-HRP 套装

sc-539555
200 µg Ab; 10 µg BP
CNY2715.00

Are there any issues with using sc-80013: MAP-2 (AA6) mouse monoclonal primary antibody on mouse samples?

Asked by: jerojero
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-80013 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by flcou from Reliable AntibodyThe antibody generated clear and reproducible results with good signal-to-noise ratio. It was straightforward to use and performed consistently in our experiments. We are satisfied with its overall quality and reliability.
Date published: 2026-06-11
Rated 5 out of 5 by StanK from good in WB and ICCAppropriately stains dendrites of mature neurons, in WB appropriately recognizes ~70 kD band in embryonic brain and ~270 kD band in mature brain.
Date published: 2018-04-13
Rated 4 out of 5 by JM from Worked well in WB in mouse transfected 293TWorked well in WB in mouse transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-03-01
Rated 4 out of 5 by JM from Good specificity in WB in human 293T wholeGood specificity in WB in human 293T whole cell lysates. -SCBT QC
Date published: 2015-02-28
Rated 4 out of 5 by MS from Positive signal in WB in mouse brain tissuePositive signal in WB in mouse brain tissue extract. -SCBT QC
Date published: 2013-12-23
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MAP-2 抗体 (AA6) is rated 4.4 out of 5 by 5.
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