JAK2 Inhibitor IV (CAS 1110502-30-1)

物理状态 :

Solid

溶解度 :

Soluble in DMSO (5 mg/ml), and ethanol (3 mg/ml).

保存 :

Store at 4° C

沸点 :

594.41° C at 760 mmHg (Predicted)

密度 :

1.31 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.65 (Predicted)

IC50 :

constitutively active V617F mutant: IC₅₀ = 206 nM; wild-type JAK2: IC₅₀ = 78 nM; JAK3: IC₅₀ = 2.93 µM

pK值 :

pK_a: 11.9 (Predicted), pK_b: 3.11 (Predicted)

PubChem CID :

MDL 号码 :

MFCD16495796

SMILES :

CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)C2=CC3=C(C=C2)NN=C3N