Date published: 2025-9-6

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Integrin α6b/ITGA6B/CD49f 抗体 (6B4): sc-59971

3.5(2)
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说明书
  • Integrin α6b/ITGA6B/CD49f 抗体 6B4 是小鼠单克隆 IgG1, 在1篇文献中引用,提供 100 µg/ml
  • 针对来自human的整合素Integrin αVIb
  • 推荐用于 human 来源的Integrin αVIb WB, IP 和 IF检测; 可能与 the basement membrane zone of ducts and acini of salivary gland, kidney tubules, epithelium of colonic crypts产生交联反应; 弱染色汗腺和皮脂腺
  • 关于如何获取Integrin α6b/ITGA6B/CD49f (6B4): sc-59971免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Integrin α6b/ITGA6B/CD49f 抗体 (6B4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Integrin αVIb 抗体(6B4)是一种小鼠单克隆 IgG1 抗体,可通过免疫印迹(WB)、免疫沉淀(IP)和免疫荧光(IF)检测人源 Integrin αVIb。抗整合素 αVIb 抗体 (6B4) 以非结合形式提供。整合素(包括整合素 αVIb)是介导细胞粘附的关键,在各种细胞过程中发挥着重要作用。整合素αVIb的结构由独特的α和β亚基组合而成,形成异二聚体,可与多种配体(如细胞外基质的成分和邻近细胞上的反受体)相互作用。这种结构上的多样性使整合素αVIb 能够参与基本的生物功能,包括影响细胞生长、分化、迁移和凋亡的细胞信号传导。整合素αVIb能够聚集并激活配体,这对于启动整合素介导的信号通路至关重要,从而使整合素αVIb成为维持组织完整性和促进细胞通讯的关键角色。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Integrin α6b/ITGA6B/CD49f 抗体 (6B4) 参考文献:

  1. beta1 整合素通过不同的机制调节角质形成细胞的粘附和分化。  |  Levy, L., et al. 2000. Mol Biol Cell. 11: 453-66. PMID: 10679006
  2. 整合素:细胞粘附中的多功能性, 调节和信号传递。  |  Hynes, RO. 1992. Cell. 69: 11-25. PMID: 1555235
  3. 破骨细胞瘤(巨细胞骨肿瘤)的单克隆抗体:破骨细胞特异性细胞抗原的定义。  |  Horton, MA., et al. 1985. Cancer Res. 45: 5663-9. PMID: 4053038
  4. 整合素和信号转导途径:走过的路。  |  Clark, EA. and Brugge, JS. 1995. Science. 268: 233-9. PMID: 7716514
  5. 受体占据和聚集在整合素跨膜功能中的协同作用  |  Miyamoto, S., et al. 1995. Science. 267: 883-5. PMID: 7846531
  6. 上皮整合素  |  Sheppard, D. 1996. Bioessays. 18: 655-60. PMID: 8760339
  7. 可溶性因子与整合素介导的细胞锚定在控制细胞生长和分化中的合作。  |  Juliano, R. 1996. Bioessays. 18: 911-7. PMID: 8939069

订购信息

产品名称产品编号规格价格数量收藏夹

Integrin α6b/ITGA6B/CD49f 抗体 (6B4)

sc-59971
100 µg/ml
RMB2377.00

Good Afternoon. I want to know if I can use it for flow cytometry and incubate with a conjugated secondary for detection

Asked by: Wolf30
Thank you for your question. We have not yet tested this antibody, Integrin αVIb (6B4): sc-59971, in flow cytometery and so this application is not recommended at this time.
Answered by: Technical Support
Date published: 2017-08-18

What is the recommended fixation method for immunofluorescence staining with Integrin αVIb (6B4): sc-59971 monoclonal antibody?

Asked by: Trav11
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10ºC methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great for Western BlotAntibody works well in human cell line HepG2 and in human salivary gland tissue extract. -SCBT QC
Date published: 2023-09-14
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Integrin α6b/ITGA6B/CD49f 抗体 (6B4) is rated 3.5 out of 5 by 2.
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