Date published: 2025-9-7

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IL-8RB 抗体 (5E8): sc-32780

3.5(4)
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说明书
  • IL-8RB抗体(5E8)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 针对表达IL-8RB的human来源小鼠B细胞淋巴瘤L1.2转染细胞
  • 推荐用于 human 来源的IL-R8B WB, IP 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 IL-8RB (E-2): sc-7304,可查看有标记的 IL-8RB 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是IL-8RB Antibody (5E8) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与IL-8RB Antibody (5E8) 打包提供(请参阅下面的订购信息)。

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関連項目

白细胞介素-8(IL-8)已被证明是一种有效的中性粒细胞趋静和激活肽,是炎症疾病的重要介质。已经鉴定出两种不同的人白细胞介素-8受体,分别被命名为IL-8RA和IL-8RB。两者都在中性粒细胞上高水平表达,在单核细胞和髓系细胞系上的表达程度较低。此外,IL-8RA亚基在T细胞(如Jurkat细胞系)中也有表达。两种IL-8R都是七次跨膜域视紫红质受体超家族的成员,因此,它们偶联G蛋白进行信号转导。这两种受体共享77%的氨基酸同源性。IL-8RA对IL-8表现出高亲和力结合,对MGSA表现出低亲和力结合,而IL-8RB对IL-8和MGSA都表现出高亲和力结合。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IL-8RB 抗体 (5E8) 参考文献:

  1. IL8和IL8RB基因变异与胃贲门腺癌和食管鳞状细胞癌的风险。  |  Savage, SA., et al. 2004. Cancer Epidemiol Biomarkers Prev. 13: 2251-7. PMID: 15598788
  2. 白细胞介素 8 及其受体(IL8、IL8RA 和 IL8RB)的多态性以及常见的 IL8 受体变体与外周血嗜酸性粒细胞计数的关系。  |  Cheong, HS., et al. 2006. J Hum Genet. 51: 781-787. PMID: 16897191
  3. 毛细胞瘤中的IL-8、IL-8RA(CXCR1)和IL-8RB(CXCR2)表达。  |  Cianga, CM., et al. 2016. Rom J Morphol Embryol. 57: 59-64. PMID: 27151689
  4. 生物信息学方法揭示了 C-X-C motif 趋化因子受体 2 在子宫内膜异位症发展过程中的关键作用。  |  Tan, A., et al. 2018. Mol Med Rep. 18: 2841-2849. PMID: 30015967
  5. 白细胞介素-8 受体 B (IL8RB) rs1126579 C>T 变异对癌症风险的影响。  |  Zhu, L., et al. 2021. Bioengineered. 12: 3367-3384. PMID: 34238119
  6. 三叉神经节中的C-X-C motif趋化因子配体1及其受体C-X-C motif趋化因子受体2有助于神经损伤引起的口面部机械异感。  |  Yang, J., et al. 2022. J Oral Rehabil. 49: 195-206. PMID: 34714950
  7. IL8RB C1208T 突变与癌症风险之间的关系:基于 5299 例病例和 6899 例对照的汇总分析。  |  Sun, HY., et al. 2022. Medicine (Baltimore). 101: e28986. PMID: 35212311
  8. 通过靶向 C-X-C motif 趋化因子受体 2,香附子苷 A 对心肌梗死有保护作用。  |  Gao, M., et al. 2024. Biomed Pharmacother. 174: 116529. PMID: 38569275
  9. 通过诱导 HO-1 表达发挥抗氧化作用的 C-X-C Motif 趋化因子配体 5 在人类前列腺基质和癌细胞中依赖于 C-X-C Motif 趋化因子受体 2。  |  Chang, KS., et al. 2024. Antioxidants (Basel). 13: PMID: 39765818
  10. 人类白细胞介素-8 受体基因 IL-8RA 和 IL-8RB 的启动子分析。  |  Sprenger, H., et al. 1995. Immunobiology. 193: 334-40. PMID: 8530163

订购信息

产品名称产品编号规格价格数量收藏夹

IL-8RB 抗体 (5E8)

sc-32780
200 µg/ml
RMB2377.00

IL-8RB (5E8): m-IgG Fc BP-HRP 套装

sc-536747
200 µg Ab; 10 µg BP
RMB2662.00

IL-8RB (5E8): m-IgGκ BP-HRP 套装

sc-533909
200 µg Ab; 40 µg BP
RMB2662.00

IL-8RB (5E8): m-IgG1 BP-HRP 套装

sc-544793
200 µg Ab; 20 µg BP
RMB2662.00

IL-8RB 抗体 (5E8) FITC

sc-32780 FITC
200 µg/ml
RMB2482.00

IL-8RB 抗体 (5E8) PE

sc-32780 PE
200 µg/ml
RMB2580.00

Can IL-8RB (5E8): sc-32780 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, IL-8RB (5E8): sc-32780 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Great FCM SignalWe used this antibody with FCM and were able to get very nice signaling from the transfection
Date published: 2017-02-08
Rated 3 out of 5 by from Strong band obtained in WB in ILStrong band obtained in WB in IL-8RB transfected CHO-K1 cells. -SCBT QC
Date published: 2015-06-30
Rated 3 out of 5 by from Large amount of positive signal observedLarge amount of positive signal observed in WB in human IL-8RB transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-01-15
Rated 3 out of 5 by from Satisfactory FCM data of CHO cells stablySatisfactory FCM data of CHO cells stably transfected with IL-8RB. -SCBT QC
Date published: 2014-08-05
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IL-8RB 抗体 (5E8) is rated 3.5 out of 5 by 4.
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