Date published: 2025-9-6
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
IGF-1 Receptor α/IGF1R Antibody (1H7) - Immunohistochemistry - Image 293981
IGF-IRα 抗体 (1H7): sc-461. 福尔马林固定, 石蜡包埋的人体软组织的免疫过氧化物酶染色, 显示脂肪细胞膜染色.
IGF-1 Receptor α/IGF1R Antibody (1H7) - Immunohistochemistry - Image 293981
IGF-IRα 抗体 (1H7): sc-461. 福尔马林固定, 石蜡包埋的人体软组织的免疫过氧化物酶染色, 显示脂肪细胞膜染色.
IGF-1 Receptor α/IGF1R Antibody (1H7) - Flow Cytometry - Image 9817
IGF-IRα (1H7) PE: sc-461 PE. HeLa 细胞的 FCM 分析. 黑线直方图代表同型对照, 正常小鼠 IgG1: sc-2866.
IGF-1 Receptor α/IGF1R Antibody (1H7) - Flow Cytometry - Image 5947
IGF-IRα (1H7) PE: sc-461 PE.人体外周血白细胞的 FCM 分析。象限标记以同种型对照正常小鼠 IgG1: sc-2866 为基础设定。
IGF-IRα 抗体 (1H7): sc-461. 福尔马林固定, 石蜡包埋的人体软组织的免疫过氧化物酶染色, 显示脂肪细胞膜染色.

IGF-1 Receptor α/IGF1R 抗体 (1H7): sc-461

4.9(7)
寫評論提問

说明书
  • IGF-1 Receptor α/IGF1R抗体(1H7)是小鼠单克隆IgG1 κ, 在52篇文献中引用，规格为200 µg/ml
  • 针对从human胎盘中纯化的IGF-I受体的
  • 抗-IGF-1 Receptor α/IGF1R 抗体 (1H7) 推荐用于 IP, IF, IHC(P) 和 FCM，检测mouse, rat 和human 来源的 IGF-IRα
  • 抗IGF-1 Receptor α/IGF1R抗体（1H7）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 还提供无叠氮化物，用于中和；抗体将阻断IGF-I与其受体的结合，sc-461 L，200 µg/0.1 ml
  • 关于如何获取IGF-1 Receptor α/IGF1R (1H7): sc-461的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是IGF-1 Receptor α/IGF1R Antibody (1H7) 适用于 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与IGF-1 Receptor α/IGF1R Antibody (1H7) 打包提供（请参阅下面的订购信息）。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

额外IGF Receptor抗体，包括IGF-IR, IGF-IR α, IGF-IR β和IGF-IIR

IGF-IRα抗体（1H7）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过免疫沉淀（IP）、免疫荧光（IF）、石蜡包埋切片免疫组织化学（IHCP）和流式细胞术（FCM）等方法检测小鼠、大鼠和人类样本中的IGF-IRα。IGF-IRα单克隆抗体（1H7）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。胰岛素样生长因子-I受体（IGF-IR）作为调节细胞生长、存活和分化等基本过程的受体酪氨酸激酶（RTK）发挥着至关重要的作用。IGF-IRα位于细胞膜上，由其配体胰岛素样生长因子-I（IGF-I）激活，后者触发一系列细胞内信号通路，包括Ras和ERK通路，最终影响基因表达和细胞行为。IGF-IRα位于细胞膜上，能够快速传递细胞外信号和细胞内反应，促进细胞及时适应生长因子。人类IGF-IR基因位于15q26.3号染色体上，编码一种前体蛋白，该蛋白被切割成α和β亚基，这凸显了其功能的复杂性和调节机制。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

IGF-1 Receptor α/IGF1R 抗体 (1H7)

sc-461
200 µg/ml
$316.00

IGF-1 Receptor α/IGF1R (1H7): m-IgG Fc BP-HRP 套装

sc-528113
200 µg Ab; 10 µg BP
$354.00

IGF-1 Receptor α/IGF1R (1H7): m-IgGκ BP-HRP 套装

sc-520413
200 µg Ab, 40 µg BP
$354.00

IGF-1 Receptor α/IGF1R (1H7): m-IgG1 BP-HRP 套装

sc-542767
200 µg Ab; 20 µg BP
$354.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) L

sc-461 L
200 µg/0.1 ml
$316.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) AC

sc-461 AC
500 µg/ml, 25% agarose
$416.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) HRP

sc-461 HRP
200 µg/ml
$316.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) FITC

sc-461 FITC
200 µg/ml
$330.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) PE

sc-461 PE
200 µg/ml
$343.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 488

sc-461 AF488
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 546

sc-461 AF546
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 594

sc-461 AF594
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 647

sc-461 AF647
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 680

sc-461 AF680
200 µg/ml
$357.00

IGF-1 Receptor α/IGF1R 抗体 (1H7) Alexa Fluor® 790

sc-461 AF790
200 µg/ml
$357.00

I am interested in the IGF-IRα Antibody (1H7): sc-461. my understanding is that it is made by hybridoma. Would it be possible that I could purchase the cell line so that I can make the antibody in house?

Asked by: Stephen Atkins
Thank you for question. We do not license our antibodies or sell the hybridoma. Please contact our Special Orders Department to inquire about the possibility of a bulk order for this antibody. Email us at [email protected]. Or you can call us directly at (800) 457-3801 option 2.
Answered by: Technical Service
Date published: 2017-05-04

How can IGF-IRα (1H7): sc-461 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: cjMara
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-461 PE) or fluoroscein (sc-461 FITC).
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_8, d_31, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_461, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 112ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from IGF-IRα expression in lungI tried several from other companies. None of them worked. See the photo for the staining of this one in lung. The staining itself looks good, but I had expected more cells to be stained.
Date published: 2018-01-19
Rated 5 out of 5 by from Beautiful immunoperoxidase membrane stainingBeautiful immunoperoxidase membrane staining in formalin fixed, paraffin-embedded human soft tissue. -SCBT QC
Date published: 2015-04-14
Rated 5 out of 5 by from Publishable flow cytometry data for use inPublishable flow cytometry data for use in human LuCaP cells. -SCBT Publication Review
Date published: 2015-03-19
Rated 5 out of 5 by from Published data for WB in human MCFPublished data for WB in human MCF-7, 293, recombinant IGF-I, breast, colon, land lung cancer cell lines. -SCBT Publication Review
Date published: 2015-03-16
Rated 5 out of 5 by from Published data for IP and WB in human U1810 cellsPublished data for IP and WB in human U1810 cells. -SCBT Publication Review
Date published: 2015-02-23
Rated 5 out of 5 by from Publishable data for IHC and WB in humanPublishable data for IHC and WB in human prostate cancer. -SCBT Publication Review
Date published: 2015-02-04
Rated 5 out of 5 by from Great FCM data of HeLa cellsGreat FCM data of HeLa cells. -SCBT QC
Date published: 2014-11-24
  • y_2025, m_8, d_31, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_461, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
IGF-1 Receptor α/IGF1R 抗体 (1H7) is rated 4.9 out of 5 by 7.
  • y_2025, m_8, d_31, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_461, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 112ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。