Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
ICAM-1/CD54 Antibody (YN1/1.7.4) - Flow Cytometry - Image 13200
ICAM-1 抗体 (YN1/1. 7. 4): sc-52553. 用 ICAM-1 抗体 (YN1/1. 7. 4) 染色的小鼠外周血白细胞的间接 FCM 分析, 然后用 PE 结合的山羊抗大鼠 IgG: sc-3740. 黑线直方图代表同型对照, 正常大鼠 IgG2b: sc-3884.
ICAM-1 抗体 (YN1/1. 7. 4): sc-52553. 用 ICAM-1 抗体 (YN1/1. 7. 4) 染色的小鼠外周血白细胞的间接 FCM 分析, 然后用 PE 结合的山羊抗大鼠 IgG: sc-3740. 黑线直方图代表同型对照, 正常大鼠 IgG2b: sc-3884.

ICAM-1/CD54 抗体 (YN1/1.7.4): sc-52553

4.0(1)
寫評論提問
说明书
  • ICAM-1/CD54 抗体 YN1/1.7.4 是大鼠单克隆 IgG2b, 在5篇文献中引用，提供 200 µg/ml
  • 针对mouse来源的NS-1细胞
  • 推荐用于 mouse 来源的ICAM-1 WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 ICAM-1/CD54 (G-5): sc-8439，可查看有标记的 ICAM-1/CD54 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前，我们还没有完成ICAM-1/CD54 抗体 (YN1/1.7.4)的首选二抗检测试剂的鉴定。这项工作正在进行中。
Gene Editing Promo Banner

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

额外ICAM抗体，包括ICAM-1, ICAM-2和ICAM-3

细胞粘附分子（CAMs）是一类在生长过程中参与细胞间相互作用的密切相关的细胞表面糖蛋白，它们在胚胎发育和成长过程中被认为起着重要但各自独立的作用。细胞内粘附分子-1（ICAM-1），也称为CD54，是免疫球蛋白超家族的一种整合膜蛋白，可识别β2α1和β2αM整合素。ICAM-2作为淋巴细胞功能相关抗原-1（LFA-1）的配体，参与白细胞粘附。ICAM-3在人嗜酸性粒细胞表面高度表达，当与配体结合时，可抑制嗜酸性粒细胞的炎症反应和存活。ICAM-4，也称为LW糖蛋白，与整合素αLβ2、αMβ2、α4β1、αV家族和αIIbβ3相互作用，选择性结合不同的整合素可能与多种红细胞相关疾病的病理学有关。最后，ICAM-5在端脑神经元上表达，与CD11a/CD18结合，因此可能作为中枢神经系统中白细胞结合的粘附分子。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ICAM-1/CD54 抗体 (YN1/1.7.4) 参考文献:

  1. ICAM-1缺乏抑制宿主对MHC差异角膜移植的同种免疫和排斥反应。  |  Zhu, SN., et al. 2000. Transplantation. 69: 1008-13. PMID: 10755569
  2. VCAM-1在早期动脉粥样硬化中发挥重要作用，但ICAM-1则不然。  |  Cybulsky, MI., et al. 2001. J Clin Invest. 107: 1255-62. PMID: 11375415
  3. sICAM-1与扩张型心肌病的心肌ICAM-1表达相关。  |  Noutsias, M., et al. 2003. Int J Cardiol. 91: 153-61. PMID: 14559125
  4. ICAM-1和LFA-1在急性髓细胞白血病中的影响。  |  Zhang, W., et al. 2006. Clin Lab Haematol. 28: 177-82. PMID: 16706934
  5. LFA-1及其配体ICAM-1和ICAM-2的力谱。  |  Wojcikiewicz, EP., et al. 2006. Biomacromolecules. 7: 3188-95. PMID: 17096550
  6. 急性心肌梗死中的ICAM-1：潜在的治疗靶点。  |  Benson, V., et al. 2007. Curr Mol Med. 7: 219-27. PMID: 17346172
  7. ICAM-1的表达决定了癌症的恶性潜能。  |  Roland, CL., et al. 2007. Surgery. 141: 705-7. PMID: 17560245
  8. ICAM-1介导小鼠角膜上皮损伤后中性粒细胞和角膜细胞之间的表面接触。  |  Gagen, D., et al. 2010. Exp Eye Res. 91: 676-84. PMID: 20713042
  9. ICAM-1缺失小鼠伤口愈合特征，这些小鼠缺乏ICAM-1的所有同种型。  |  Gay, AN., et al. 2011. J Surg Res. 171: e1-7. PMID: 21872884
  10. 根尖周囊肿和残余囊肿中 ICAM-1, TGF-β1 和 ki-67 的免疫表达比较。  |  Martins, R., et al. 2017. Med Oral Patol Oral Cir Bucal. 22: e24-e30. PMID: 27918735

订购信息

产品名称产品编号规格价格数量收藏夹

ICAM-1/CD54 抗体 (YN1/1.7.4)

sc-52553
200 µg/ml
$322.00

ICAM-1/CD54 抗体 (YN1/1.7.4) FITC

sc-52553 FITC
200 µg/ml
$336.00

ICAM-1/CD54 抗体 (YN1/1.7.4) PE

sc-52553 PE
200 µg/ml
$349.00

Do you offer FREE 10 µg sample for this product (ICAM-1 Antibody (YN1/1.7.4): sc-52553 )?

Asked by: Bohua Hu
Thank you for your question. No, we do not provide a free 10 µg sample of this specific antibody, ICAM-1 (YN1/1.7.4): sc-52553. We do warranty the antibody for the recommended applications and species. For a list of alternative ICAM-1 antibodies for which we do offer a free 10 µg sample, please refer to the antibody table below. https://www.scbt.com/scbt/browse/icam-1-Antibodies/_/N-akv2w8
Answered by: Technical Support
Date published: 2017-10-11

Can ICAM-1 (YN1/1.7.4): sc-52553 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Professor Griffin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, ICAM-1 (YN1/1.7.4): sc-52553 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_24, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_52553, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 110ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by MS from Produced wonderful indirect FCM data forProduced wonderful indirect FCM data for mouse peripheral blood leukocytes stained with ICAM-1 . -SCBT QC
Date published: 2014-05-30
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_52553, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
ICAM-1/CD54 抗体 (YN1/1.7.4) is rated 4.0 out of 5 by 1.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_52553, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 108ms
  • REVIEWS, PRODUCT
1-800-457-3801
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打1-800-457-3801联系我们。
版权所有© 2007-2026 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。