Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

hnRNP A2/B1 抗体 (E-2): sc-374052

4.8(6)
寫評論提問
说明书
  • hnRNP A2/B1抗体(E-2)是小鼠单克隆IgG1 κ, 在6篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的hnRNP A2/B1的内部区域内的氨基酸209-243之间
  • 推荐用于 mouse, rat 和 human 来源的hnRNP A2/B1 WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine and porcine
  • 看 hnRNP A2/B1 (B-7): sc-374053,可查看有标记的 hnRNP A2/B1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgGκ BP-HRP是hnRNP A2/B1 Antibody (E-2) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现可与hnRNP A2/B1 Antibody (E-2) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。
Gene Editing Promo Banner

快捷链接

関連項目

异质性核核糖核蛋白(hnRNPs)是一组多肽,有助于mRNA转录和前mRNA处理,以及成熟mRNA向细胞质的转运和翻译。它们还与异质性核RNA(hnRNA)结合,这是由RNA聚合酶II产生的转录物。已知大约有20种hnRNP蛋白,它们的复合物是剪接体的主要组成部分。大多数hnRNP蛋白定位于细胞核;然而有些在细胞核和细胞质之间穿梭。hnRNPs的A/B亚家族包括A1、A2/B1、A3和A0,在非洲爪蟾中,hnRNP A1、A2和A3在整个发育过程以及成年组织中普遍表达。hnRNP A1和A2/B1通过直接拮抗各种剪接因子的结合以及影响前mRNA上的剪接位点选择来调节前mRNA的加工。hnRNP A0基因与其他A/B家族成员不同,它编码一种低丰度蛋白,与mRNA稳定性有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

hnRNP A2/B1 抗体 (E-2) 参考文献:

  1. 睾丸和发育阶段特异性表达的hnRNP A2/B1剪接异构体B0a/b。  |  Matsui, M., et al. 2000. Biochim Biophys Acta. 1493: 33-40. PMID: 10978504
  2. hnRNP A2/B1、hnRNP B1和S100 A2在非小细胞肺癌中的预后和诊断相关性。  |  Zech, VF., et al. 2006. Cancer Detect Prev. 30: 395-402. PMID: 17067748
  3. hnRNP A2/B1在核基质中的定位以及人类神经母细胞瘤SK-N-SH细胞在RA诱导分化过程中的异常表达。  |  Liang, Y., et al. 2011. J Cell Biochem. 112: 1722-9. PMID: 21321999
  4. TDP-43通过与HnRNP A2/B1相互作用抑制CGG重复引起的神经毒性。  |  He, F., et al. 2014. Hum Mol Genet. 23: 5036-51. PMID: 24920338
  5. 人类hnRNP A2/B1对RNA底物进行特异性和多变量识别的分子基础。  |  Wu, B., et al. 2018. Nat Commun. 9: 420. PMID: 29379020
  6. β-细辛醚通过抑制剪接因子hnRNP A2/B1抑制人胶质瘤U251细胞的侵袭和EMT。  |  Li, L., et al. 2018. Molecules. 23: PMID: 29547514
  7. IE86通过hnRNP A2/B1介导的Bcl-x的替代剪接抑制胶质瘤细胞的凋亡并促进其增殖。  |  Zhao, R., et al. 2019. Int J Clin Exp Pathol. 12: 2775-2785. PMID: 31934113
  8. 慢性口服贫铀通过ROS-hnRNP A2/B1-COX-2信号通路导致雄性大鼠的生殖损伤。  |  Lu, B., et al. 2021. Toxicology. 449: 152666. PMID: 33359576
  9. CHD1L通过激活hnRNP A2/B1-nmMYLK轴来防止脂多糖诱导的肝细胞癌细胞死亡。  |  Wang, G., et al. 2021. Cell Death Dis. 12: 891. PMID: 34588420
  10. 分子表征的hnRNP A2/B1蛋白:组织特异性表达和新的同种型。  |  Kamma, H., et al. 1999. Exp Cell Res. 246: 399-411. PMID: 9925756

订购信息

产品名称产品编号规格价格数量收藏夹

hnRNP A2/B1 抗体 (E-2)

sc-374052
200 µg/ml
CNY2422.00

hnRNP A2/B1 (E-2): m-IgGκ BP-HRP 套装

sc-535376
200 µg Ab; 40 µg BP
CNY2715.00

hnRNP A2/B1 (E-2) 中和勝肽

sc-374052 P
100 µg/0.5 ml
CNY519.00

What application is the blocking peptide sc-374052 P appropriate for?

Asked by: Trav11
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_23, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_374052, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 126ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by Germaine from Produced publishable WB data in HumanThis hnRNP A2/B1 monoclonal antibody was referenced in a publication being used for WB on human Be(2)C cells.
Date published: 2017-02-01
Rated 4 out of 5 by HC from Used this antibody in WB and works well inUsed this antibody in WB and works well in mouse tissues.
Date published: 2015-10-01
Rated 5 out of 5 by QZ from Worked great for Western with KWorked great for Western with K-562 and THP-1 nuclear extracts. -SCBT QC
Date published: 2015-03-26
Rated 5 out of 5 by HC from Nice IF staining with methanolNice IF staining with methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-03-16
Rated 5 out of 5 by CJ from WB positive in methanolWB positive in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-03-15
Rated 5 out of 5 by JM from Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human esophagus tissue. -SCBT QC
Date published: 2015-02-16
  • y_2026, m_10, d_23, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_374052, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
hnRNP A2/B1 抗体 (E-2) is rated 4.8 out of 5 by 6.
  • y_2026, m_10, d_23, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_374052, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 100ms
  • REVIEWS, PRODUCT