Date published: 2025-9-7

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GFAP 抗体 (1.BB.807): sc-71143

4.3(3)
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说明书
  • GFAP 抗体 1.BB.807 是小鼠单克隆 IgG2b, 在10篇文献中引用,提供 100 µg/ml
  • 针对human大脑的纯化胶质纤维酸性蛋白
  • 推荐用于 mouse, rat 和 human 来源的43-45 kDa fragment of GFAP WB, IP 和 IF检测
  • 看 GFAP (2E1): sc-33673,可查看有标记的 GFAP 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成GFAP 抗体 (1.BB.807)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

GFAP抗体(1.BB.807)是一种小鼠单克隆IgG2b抗体,专门用于检测中枢神经系统星形胶质细胞中一种重要的中间丝蛋白--酸性成纤维细胞蛋白(GFAP)。抗GFAP抗体(1.BB.807)针对纯化的人脑GFAP制备,能够可靠地识别小鼠、大鼠和人类中的GFAP,因此非常适合用于蛋白质印迹(WB)、免疫沉淀(IP)和免疫荧光(IF)等应用。GFAP由氨基端头域、中央棒状域和羧基尾端域组成,这些结构对于组装成稳定的细胞骨架网络至关重要。这种结构使GFAP能够与vimentin、nestin、alphaB-crystallin和plectin等蛋白质相互作用,从而促进细胞过程,例如维持细胞形状、细胞内运输和对损伤的反应。这些相互作用对于星形胶质细胞的功能和恢复力至关重要,尤其是在星形胶质增生期间,这种增生是对神经损伤的反应,其特点是GFAP表达增加。GFAP单克隆抗体(1.BB.807)是研究人员研究神经健康和疾病的分子机制的宝贵工具,有助于深入了解GFAP及其相互作用伴侣在维持中枢神经系统完整性方面的作用。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

GFAP 抗体 (1.BB.807)

sc-71143
100 µg/ml
$316.00

If it is possible to get this antibody in 50 Ug/ml.

Asked by: poonkuzhali
Thank you for your question. We only provide GFAP Antibody (1.BB.807): sc-71143 at a concentration of at 100 µg/ml.
Answered by: Tech Support Europe
Date published: 2019-05-15

I am using GFAP (1.BB.807): sc-71143 for immunofluorescence, what dilution of this antibody should I use?

Asked by: jerojero
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from GFAP Antibody in immunoblottingAb worked as expected for detecting the GFAP. Combined with Ub Ab (sc-8017), we now know that the GFAP is mono-ubiquitinated when the cells used are treated with EF24 or CLefma
Date published: 2019-02-07
Rated 5 out of 5 by from gave excellent signalThis antibody gave excellent signal, and very little background. The signal was so strong that there was some bleed-through into the 488 channel.
Date published: 2017-01-22
Rated 3 out of 5 by from Strong signal observed in WB using transfectedStrong signal observed in WB using transfected lysates. -SCBT QC
Date published: 2013-06-19
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GFAP 抗体 (1.BB.807) is rated 4.3 out of 5 by 3.
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