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galectin-7 Antibody (A-8) - Western Blotting - Image 325099
galectin-7 抗体 (A-8): sc-271473. Western 印迹分析 SCC-4 全细胞裂解液中 galectin-7 的表达.
galectin-7 抗体 (A-8): sc-271473. Western 印迹分析 SCC-4 全细胞裂解液中 galectin-7 的表达.

galectin-7 抗体 (A-8): sc-271473

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说明书
  • galectin-7抗体(A-8)是小鼠单克隆IgG3 (kappa轻链)，规格为200 µg/ml
  • 特异性抗原位于human物种的galectin-7的内部区域内的氨基酸41-91之间
  • 推荐用于 mouse, rat 和 human 来源的galectin-7 WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG3 BP-HRP 是galectin-7 抗体 (A-8) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与galectin-7 抗体 (A-8) 组合成套装提供。 (请参阅下面的订购信息)。

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    描述
    基因信息
    说明书与实验方案
    研究信息

    関連項目

    此外 galectin 抗体包括 galectin-1, galectin-10, galectin-2, galectin-3, galectin-4, galectin-5, galectin-7 和 galectin-8

    Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galectin-7, expressed mainly in stratified squamous epithelium, is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. The galectin-7 gene maps to chromosome 19.

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    galectin-7 抗体 (A-8) 参考文献:

    1. 半乳糖凝集素-7在损伤后表皮稳态的调控中。  |  Gendronneau, G., et al. 2008. Mol Biol Cell. 19: 5541-9. PMID: 18829868
    2. 人类和鼠类黑色素瘤中半乳糖凝集素-7的表达和功能。  |  Biron-Pain, K., et al. 2013. PLoS One. 8: e63307. PMID: 23658821
    3. 上皮细胞表面的E-钙粘蛋白动态受半乳糖凝集素-7调控。  |  Advedissian, T., et al. 2017. Sci Rep. 7: 17086. PMID: 29213102
    4. Galectin-7通过抑制TGFβ/Smad3通路，促进活化CD4+ T细胞增殖和Th1/2细胞向Th1细胞分化。  |  Luo, Z., et al. 2018. Mol Immunol. 101: 80-85. PMID: 29890367
    5. 芍药苷通过lncRNA NEAT1/miR-3194-5p/半乳糖凝集素-7轴抑制银屑病角质形成细胞的增殖和迁移。  |  Wang, D., et al. 2022. Anticancer Drugs. 33: e423-e433. PMID: 34459454
    6. CCCTC 结合因子转录调节 Galectin-7 并激活 JNK/STAT3 轴，从而加重支气管上皮细胞损伤。  |  Sun, X., et al. 2022. Pediatr Pulmonol. 57: 90-99. PMID: 34643340
    7. 人类Galectin-7基因LGALS7启动子序列多态性与自发性脑出血风险：一项前瞻性研究。  |  Wang, MD., et al. 2022. Front Mol Neurosci. 15: 840340. PMID: 35401111
    8. 人类肺癌中galectin-7的表达和预后影响。  |  Tirilomi, A., et al. 2024. Medicine (Baltimore). 103: e39911. PMID: 39465762
    9. 靶向半乳糖凝集素-7/TRPM2/Zn2+/DRP-1信号通路：SJS/TEN发病机理的潜在治疗干预。  |  Zhang, C., et al. 2025. Allergy.. PMID: 40042066
    10. Galectin-7 是所有类型分层上皮细胞的标记。  |  Magnaldo, T., et al. 1998. Differentiation. 63: 159-68. PMID: 9697310

    订购信息

    产品名称产品编号规格价格数量收藏夹

    galectin-7 抗体 (A-8)

    sc-271473
    200 µg/ml
    		RMB2377.00

    galectin-7 (A-8): m-IgG3 BP-HRP 套装

    sc-550406
    200 µg Ab; 40 µg BP
    		RMB2662.00

    galectin-7 (A-8) 中和勝肽

    sc-271473 P
    100 µg/0.5 ml
    		RMB511.00

    What application is the blocking peptide sc-271473 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Pityit's a little hard to get a clean band, because it has a small KD
    Date published: 2017-03-15
    Rated 5 out of 5 by from Beautiful immunoperoxidase cytoplasmic stainingBeautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human vulva/anal skin tissue. -SCBT QC
    Date published: 2015-04-10
    Rated 5 out of 5 by from Strong band in WB in human galectinStrong band in WB in human galectin-7 transfected 293T whole cell lysate. -SCBT QC
    Date published: 2015-03-17
    Rated 5 out of 5 by from Robust band seen in WB in SCCRobust band seen in WB in SCC-4 whole cell lysate. -SCBT QC
    Date published: 2015-02-11
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    galectin-7 抗体 (A-8) is rated 5.0 out of 5 by 4.
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