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FGF-2 抗体 (A-7): sc-74413

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说明书
  • FGF-2抗体(A-7)是小鼠单克隆IgG2a κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的FGF-2的氨基酸10-140
  • 推荐用于WB, IP, IF和ELISA检测mouse, rat, human和Xenopus来源的precursor and mature FGF-2
  • 看 FGF-2 (G-2): sc-365106,可查看有标记的 FGF-2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 2a BP-HRP">m-IgG2a BP-HRP是FGF-2 Antibody (A-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与FGF-2 Antibody (A-7) 打包提供(请参阅下面的订购信息)。
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関連項目

成纤维细胞生长因子-1 (FGF-1),又称酸性FGF,成纤维细胞生长因子-2 (FGF-2),又称碱性FGF,它们属于生长因子家族,可以刺激间充质细胞、上皮细胞和神经外胚层细胞增殖。FGF家族还包括癌基因 FGF-3 (Int2) 和 FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) 和 FGF-10-FGF-23。FGF家族成员具有 30-55%的氨基酸序列同一性,有相似的基因结构,在转染细胞过表达时,能转化培养细胞。FGFs 细胞受体属于另一种多基因家族,其中包括四种酪氨酸激酶,分别为 Flg (FGFR-1), Bek (FGFR-L), TKF 和 FGFR-3。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FGF-2 抗体 (A-7) 参考文献:

  1. PLAP-1/Asporin 可积极调节 FGF-2 的活性。  |  Awata, T., et al. 2015. J Dent Res. 94: 1417-24. PMID: 26239644
  2. FGF-2可通过增加E11/podoplanin的表达促进骨细胞分化。  |  Ikpegbu, E., et al. 2018. J Cell Physiol. 233: 5334-5347. PMID: 29215722
  3. VEGF和FGF-2:治疗呼吸系统疾病的有效靶点。  |  Laddha, AP. and Kulkarni, YA. 2019. Respir Med. 156: 33-46. PMID: 31421589
  4. FGF-2在颅面骨组织工程中的潜力:综述。  |  Novais, A., et al. 2021. Cells. 10: PMID: 33920587
  5. FGF-2通过调节蛛网膜下腔出血中的PI3K/Akt通路抑制神经元自噬。  |  Wang, Y., et al. 2021. Brain Res Bull. 173: 132-140. PMID: 34023434
  6. 在衰老的人体骨骼肌中激活的FGF-2依赖性信号传导促进肌内脂肪生成。  |  Mathes, S., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 34493647
  7. 药理学FGF-2的抗纤维化作用:近期文献综述。  |  Dolivo, DM. 2022. J Mol Med (Berl). 100: 847-860. PMID: 35484303
  8. FGF-2可增强TGF-β2处理的人结膜成纤维细胞的纤维化变化。  |  Tsugeno, Y., et al. 2022. Sci Rep. 12: 16006. PMID: 36163231
  9. 使用毕赤酵母菌(Pichia pastoris)提高抗FGF-2纳米抗体的产量及其对角质形成细胞增殖抑制和缓解牛皮癣的作用。  |  Zhou, Z., et al. 2023. Arch Immunol Ther Exp (Warsz). 71: 20. PMID: 37632545
  10. 机械应力诱导的FGF-2可促进间充质干细胞的增殖并因此诱导成骨细胞分化。  |  Ogura, H., et al. 2023. Biochem Biophys Res Commun. 684: 149145. PMID: 37913587

订购信息

产品名称产品编号规格价格数量收藏夹

FGF-2 抗体 (A-7)

sc-74413
200 µg/ml
CNY2422.00

FGF-2 (A-7): m-IgG Fc BP-HRP 套装

sc-539513
200 µg Ab; 10 µg BP
CNY2715.00

FGF-2 (A-7): m-IgG2a BP-HRP 套装

sc-546718
200 µg Ab; 10 µg BP
CNY2715.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with FGF-2 (A-7): sc-74413 monoclonal antibody?

Asked by: Cweed
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
  • y_2026, m_10, d_24, h_5CST
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Rated 1 out of 5 by Bren1 from Did not recognize rat FGF-2I tried this antibody out to detect rat FGF-2. I tested it by running it in a Western blot against recombinant rat FGF-2. This antibody did not detect the protein while other ones did. It did not detect either reduced or non reduced recombinant rat FGF-2.
Date published: 2018-11-14
Rated 4 out of 5 by Mamta from lab managerI bought this a month ago. It did not work for our purpose. But santa Cruz has promised us to send free replacement
Date published: 2018-10-31
Rated 5 out of 5 by HF from Strong band in WB in human recombinant FGFStrong band in WB in human recombinant FGF-2.
Date published: 2014-10-03
Rated 5 out of 5 by FL from Good Western blot data of human recombinant FGFGood Western blot data of human recombinant FGF-2. -SCBT QC
Date published: 2014-10-03
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FGF-2 抗体 (A-7) is rated 3.8 out of 5 by 4.
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  • cp_1, bvpage1
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