Date published: 2025-9-6

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FGF-1 抗体 (D-11): sc-13123

5.0(1)
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说明书
  • FGF-1抗体(D-11)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 免疫human物种的FGF-1的氨基酸16-140
  • 推荐用于 human 来源的precursor and mature FGF-1 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是FGF-1 Antibody (D-11) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与FGF-1 Antibody (D-11) 打包提供(请参阅下面的订购信息)。

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    関連項目

    FGF-1(也称酸性FGF)和FGF-2(也称基础FGF)是一类生长因子家族的成员,能够刺激间充质、上皮和神经外胚层细胞的增殖。FGF家族的其他成员包括致癌基因FGF-3(Int2)和FGF-4(hst/Kaposi)、FGF-5、FGF-6、FGF-7(KGF)、FGF-8(AIGF)、FGF-9(GAF)和FGF-10-FGF-23。FGF家族成员的氨基酸序列相似度在30-55%,基因结构也相似,在转染细胞中过表达时能够转换培养细胞。FGF的细胞受体是第二个多基因家族的成员,包括四种酪氨酸激酶,分别称为Flg(FGFR-1)、Bek(FGFR-L)、TKF和FGFR-3。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    FGF-1 抗体 (D-11) 参考文献:

    1. FGF-1/FGFR 信号系统网络图  |  Raju, R., et al. 2014. J Signal Transduct. 2014: 962962. PMID: 24829797
    2. FGF-1 对软骨细胞的分解作用及其在骨关节炎中可能发挥的作用  |  El-Seoudi, A., et al. 2017. J Cell Commun Signal. 11: 255-263. PMID: 28343287
    3. CRTC1 对 Fgf1 转录物的表观遗传调控与记忆增强。  |  Uchida, S. and Shumyatsky, GP. 2018. Brain Res Bull. 141: 3-12. PMID: 29477835
    4. 脂肪细胞 Piezo1 通过 FGF1/FGFR1 信号通路介导小鼠肥胖性脂肪生成。  |  Wang, S., et al. 2020. Nat Commun. 11: 2303. PMID: 32385276
    5. FGF1ΔHBS通过抑制AMPK/Nur77来维持线粒体稳态并减少氧化应激,从而预防糖尿病性心肌病。  |  Wang, D., et al. 2021. Signal Transduct Target Ther. 6: 133. PMID: 33762571
    6. MicroRNA-27b-3p 下调 FGF1 并加重病理性心脏重塑。  |  Li, G., et al. 2022. Cardiovasc Res. 118: 2139-2151. PMID: 34358309
    7. FGF1 和胰岛素通过趋同途径控制脂肪分解。  |  Sancar, G., et al. 2022. Cell Metab. 34: 171-183.e6. PMID: 34986332
    8. FGF1 可通过抑制炎症和氧化应激减轻 LPS 引起的急性肺损伤。  |  Dhlamini, Q., et al. 2022. Mol Med. 28: 73. PMID: 35764933
    9. 外源性 FGF-1 对 SCI 修复模型和培养细胞中的少突胶质细胞补充具有不同的调控作用。  |  Lee, MJ., et al. 2022. Biomedicines. 10: PMID: 36359244
    10. 血小板沉积在涂有或未涂有 FGF-1 和肝素的纤维蛋白胶的 ePTFE 移植物上。  |  Zarge, JI., et al. 1997. J Surg Res. 67: 4-8. PMID: 9070173

    订购信息

    产品名称产品编号规格价格数量收藏夹

    FGF-1 抗体 (D-11)

    sc-13123
    200 µg/ml
    RMB2377.00

    FGF-1 (D-11): m-IgG Fc BP-HRP 套装

    sc-536573
    200 µg Ab; 10 µg BP
    RMB2662.00

    FGF-1 (D-11): m-IgGκ BP-HRP 套装

    sc-533724
    200 µg Ab; 40 µg BP
    RMB2662.00

    FGF-1 (D-11): m-IgG2b BP-HRP 套装

    sc-549813
    200 µg Ab; 10 µg BP
    RMB2662.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with FGF-1 (D-11): sc-13123?

    Asked by: Professor Griffin
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Worked well with human recombinant FGFWorked well with human recombinant FGF-1 by WB. -SCBT QC
    Date published: 2014-07-02
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    FGF-1 抗体 (D-11) is rated 5.0 out of 5 by 1.
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