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FcRn Antibody (H-4) - Western Blotting - Image 73050 — FcRn 抗体 (H-4): sc-166413. 非转染: sc-117752 (A) 和小鼠 FcRn 转染: sc-126843 (B) 293T 全细胞裂解液中 FcRn 表达的 Western 印迹分析.

FcRn 抗体 (H-4): sc-166413. 非转染: sc-117752 (A) 和小鼠 FcRn 转染: sc-126843 (B) 293T 全细胞裂解液中 FcRn 表达的 Western 印迹分析.

FcRn 抗体 (H-4): sc-166413

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寫評論提問

说明书

FcRn抗体(H-4)是小鼠单克隆IgG₁ κ, 在3篇文献中引用，规格为200 µg/ml
针对FcRn的mouse起源的N-terminal细胞外域内的氨基酸22-276
推荐用于 mouse, rat 和 human 来源的FcRn WB, IP, IF 和 ELISA检测
看 FcRn (B-8): sc-271745，可查看有标记的 FcRn 抗体，包括AC, HRP, FITC, PE, Alexa Fluor^® 488, 594, 647, 680 和 790
m-IgG Fc BP-HRP和 m-IgG₁ BP-HRP是FcRn Antibody (H-4) for WB applications. 的首选辅助检测试剂，这些试剂现与FcRn Antibody (H-4) 打包提供（请参阅下面的订购信息）。

查看产品引用文献(3)

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FcRn 抗体 (H-4) 参考文献:

为增强与新生儿Fc受体（FcRn）的结合而设计的人IgG1s的特性。 | Dall'Acqua, WF., et al. 2006. J Biol Chem. 281: 23514-24. PMID: 16793771
新生儿Fc受体（FcRn）以相同的亲和力分别与IgG同二聚体的两个位点结合。 | Abdiche, YN., et al. 2015. MAbs. 7: 331-43. PMID: 25658443
FcRn在神经免疫疗法中的重要性：从IgG分解代谢、FCGRT基因多态性、IVIg剂量和效率到特异性FcRn抑制剂。 | Dalakas, MC. and Spaeth, PJ. 2021. Ther Adv Neurol Disord. 14: 1756286421997381. PMID: 33717213
血清白蛋白的临床意义和FcRn抑制剂治疗IgG介导的自身免疫性疾病的影响。 | Ward, ES., et al. 2022. Front Immunol. 13: 892534. PMID: 35757719
FcRn抑制剂Batoclimab治疗甲状腺眼病的概念验证和随机安慰剂对照试验。 | Kahaly, GJ., et al. 2023. J Clin Endocrinol Metab. 108: 3122-3134. PMID: 37390454
FcRN受体拮抗剂在重症肌无力治疗中的应用。 | Bhandari, V. and Bril, V. 2023. Front Neurol. 14: 1229112. PMID: 37602255
一种针对FcRn的粘膜疫苗，可预防SARS-CoV-2感染和传播。 | Li, W., et al. 2023. Nat Commun. 14: 7114. PMID: 37932271
FcRn抑制剂在重症肌无力患者中的疗效和安全性：系统评价和荟萃分析。 | Li, J., et al. 2024. J Neurol. 271: 2298-2308. PMID: 38431900
Efgartigimod作为新型FcRn抑制剂治疗自身免疫性疾病。 | Yang, Y., et al. 2024. Neurol Sci. 45: 4229-4241. PMID: 38644454
FcRn抑制剂疗法在神经疾病中的应用。 | Alfaidi, N., et al. 2024. CNS Drugs. 38: 425-441. PMID: 38724842

种属	基因名称	基因ID	染色体位置	亚型（mRNA）登录号	蛋白质登录号	OMIM™ 号码
Human	FCGRT	Entrez Gene ID: 2217	19q13.33	XM_005258657, XM_011526627, NM_001136019, NM_004107	UniProt ID: P55899	601437
Mouse	Fcgrt	Entrez Gene ID: 14132	7 B4	XM_006540603, NM_010189	UniProt ID: Q61559	N/A

订购信息

产品名称	产品编号	规格	价格	数量	收藏夹
FcRn 抗体 (H-4)	sc-166413	200 µg/ml	$322.00
FcRn (H-4): m-IgG Fc BP-HRP 套装	sc-540098	200 µg Ab; 10 µg BP	$361.00
FcRn (H-4): m-IgG₁ BP-HRP 套装	sc-541902	200 µg Ab; 20 µg BP	$361.00

what is the recommended conc of FcRn Antibody (H-4): sc-166413 when analysing wt mouse FcRN from homogenised liver tissue?   

Asked by: esben axelgaard

Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-166413.pdf If you have any further questions or concerns, please contact our Technical Service, emailing [email protected], or using the Live Chat function on our website.

Answered by: Technical Support Europe

Date published: 2017-09-26

Do you offer a free sample of FcRn Antibody (H-4): sc-166413 ?

Asked by: esben axelgaard

Thank you for your question. Unfortunately we do not offer a sample of sc-166413, our FcRN antibody. However, we do offer a sample of two of our other FcRN antibodies, sc-271745 SAMPLE FcRn (B-8) and sc-393064 SAMPLE FcRn (A-6). If you would like a sample of these, please contact your local distributor or our European office.

Answered by: Tech Service

Date published: 2017-06-02

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-166413: FcRn (H-4) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp

Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.

Answered by: Technical Support

Date published: 2017-03-06

Rated 3 out of 5 by Geetika from Different results with every IHC stainingOur lab bought this antibody for immunofluorescence on paraformaldehyde fixed tissues and observed variability across different lots.

Date published: 2017-08-07

Rated 4 out of 5 by LF from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC

Date published: 2015-03-23

Rated 5 out of 5 by CJ from neutralization publishable data with rat sampleneutralization publishable data with rat sample - SCBT Publication Review

Date published: 2013-07-23

FcRn 抗体 (H-4) is rated 4.0 out of 5 by 3.

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FcRn 抗体 (H-4): sc-166413

FcRn 抗体 (H-4) 参考文献:

優選的 FcRn 抗體是 FcRn 抗體 (B-8): sc-271745.

FcRn 抗体 (H-4)

FcRn (H-4): m-IgG Fc BP-HRP 套装

FcRn (H-4): m-IgG1 BP-HRP 套装

what is the recommended conc of&nbsp;FcRn Antibody (H-4): sc-166413 when analysing wt mouse FcRN from homogenised liver tissue? &nbsp;&nbsp;

Do you offer a free sample of&nbsp;FcRn Antibody (H-4): sc-166413 ?

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-166413: FcRn (H-4) mouse monoclonal antibody will work?

FcRn (H-4): m-IgG₁ BP-HRP 套装

what is the recommended conc of FcRn Antibody (H-4): sc-166413 when analysing wt mouse FcRN from homogenised liver tissue?

Do you offer a free sample of FcRn Antibody (H-4): sc-166413 ?