Date published: 2025-9-7

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FANCG 抗体 (75-A): sc-100740

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说明书
  • FANCG抗体(75-A)是小鼠单克隆IgG2a (kappa轻链),规格为100 µg/ml
  • 免疫human物种的重组FANCG
  • 推荐用于 human 来源的FANCG WB, IP, IF 和 ELISA检测
  • 目前,我们还没有完成FANCG 抗体 (75-A)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    FANCG抗体(75-A)是一种小鼠单克隆IgG2a抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测人类样本中的FANCG。FANCG在范可尼贫血(FA)通路中起着至关重要的作用,该通路对于维持基因组稳定性和修复DNA交联至关重要。FANCG主要位于细胞核中,参与受损DNA的修复,其正常功能对于防止染色体不稳定(FANCG的典型特征)至关重要。FANCG的调控,尤其是通过翻译后修饰(如磷酸化)的调控非常重要;例如,FANCG中丝氨酸7的磷酸化对于FANCG在FA通路中的作用至关重要。这种修饰增强了FANCG对DNA损伤的反应能力,从而保护细胞完整性。FANCG在睾丸和胸腺中高度表达,表明FANCG在涉及这些组织的细胞过程中非常重要。抗FANCG抗体(75-A)是研究Fanconi贫血和相关基因组稳定性紊乱分子机制的研究人员的重要工具。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    FANCG 抗体 (75-A)

    sc-100740
    100 µg/ml
    RMB2504.00

    I am using FANCG (75-A): sc-100740 for immunofluorescence, what dilution of this antibody should I use?

    Asked by: DefinitelyNotMatt
    Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-03-24
    • y_2025, m_8, d_30, h_9CST
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    Rated 3 out of 5 by from Good band seen in WB in HeLa nuclear extractGood band seen in WB in HeLa nuclear extract. -SCBT QC
    Date published: 2015-05-04
    Rated 3 out of 5 by from Good immunofluorescence nuclear stainingGood immunofluorescence nuclear staining in paraformaldehyde-fixed HeLa cells. -SCBT QC
    Date published: 2015-02-20
    Rated 3 out of 5 by from GoodGood, clear band in WB in human FANCG transfected 293T whole cell lysate. -SCBT QC
    Date published: 2015-01-22
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    FANCG 抗体 (75-A) is rated 3.0 out of 5 by 3.
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