Date published: 2025-9-7

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epsin 1 抗体 (G-11): sc-55564

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说明书
  • epsin 1抗体(G-11)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对epsin 1的311-440氨基酸human来源
  • 推荐用于 mouse, rat 和 human 来源的epsin 1 WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 epsin 1 抗体 (G-11) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与epsin 1 抗体 (G-11) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Epsin 1(EPN1)是一种内吞辅助蛋白,与Xenopus有丝分裂磷蛋白MP90具有显著相似性。Epsin 1与Eps15(网格蛋白适配器AP2的α亚基)、网格蛋白和其他辅助蛋白相互作用。这些蛋白的有丝分裂磷酸化可能是有丝分裂中网格蛋白包被凹坑内陷被阻断的机制之一。Epsin和Eps15与其他突触囊泡内吞机制的胞质组分一样,在神经末梢经历组成性磷酸化和去极化依赖性去磷酸化。Epsin 1还有助于网格蛋白-囊泡依赖性内吞作用的机制。人类Epsin 1蛋白包含一个epsin N端同源(ENTH)区域和一个单一的网格蛋白结合(LVDLD)基序。Epsin 1定位于囊泡包被凹坑的前缘,即膜正在积极弯曲的地方。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

epsin 1 抗体 (G-11) 参考文献:

  1. 蛋白质之间的挤压导致膜弯曲  |  Stachowiak, JC., et al. 2012. Nat Cell Biol. 14: 944-9. PMID: 22902598
  2. 利用硅学对接实验阐明小型化学物质对 PtdInsP 结合结构域的不同抑制机制。  |  Kim, Y. and Yoon, Y. 2014. Bioorg Med Chem Lett. 24: 2256-62. PMID: 24736117
  3. 泛素化缺陷的表皮生长因子受体突变体通过凝集素包被坑的内吞是由泛素化介导的  |  Fortian, A., et al. 2015. Traffic. 16: 1137-54. PMID: 26251007
  4. M2 两性螺旋的膜重塑驱动流感病毒膜裂解。  |  Martyna, A., et al. 2017. Sci Rep. 7: 44695. PMID: 28317901
  5. 在哺乳动物细胞中,内吞蛋白被分隔在凝集素晶格的边缘。  |  Sochacki, KA., et al. 2017. Nat Cell Biol. 19: 352-361. PMID: 28346440
  6. Epsins通过控制Notch活化调控小鼠胚胎干细胞从多能性和神经承诺中退出。  |  Cardano, M., et al. 2019. Stem Cells Int. 2019: 4084351. PMID: 30930949
  7. 通过三聚体增强膜重塑蛋白肽的活性。  |  Hsu, WY., et al. 2020. Bioorg Med Chem Lett. 30: 127190. PMID: 32317210
  8. EPSIN1 通过调节质膜上模式识别受体的丰度促进植物免疫  |  Zhang, W. 2020. Plant Physiol. 183: 3-4. PMID: 32385169
  9. 利用硅胶珠上的支撑双分子层进行拉降分析膜表面蛋白质与蛋白质之间的相互作用  |  Andhare, DS., et al. 2022. J Membr Biol. 255: 591-597. PMID: 35226119
  10. Intersectin1 通过组织和稳定内吞蛋白相互作用网络,促进凝集素介导的内吞作用。  |  Jin, M., et al. 2024. Cell Rep. 43: 114989. PMID: 39580802

订购信息

产品名称产品编号规格价格数量收藏夹

epsin 1 抗体 (G-11)

sc-55564
200 µg/ml
RMB2377.00

epsin 1 (G-11): m-IgG Fc BP-HRP 套装

sc-537078
200 µg Ab; 10 µg BP
RMB2662.00

epsin 1 (G-11): m-IgGκ BP-HRP 套装

sc-534265
200 µg Ab; 40 µg BP
RMB2662.00

epsin 1 (G-11): m-IgG1 BP-HRP 套装

sc-544991
200 µg Ab; 20 µg BP
RMB2662.00

Can epsin 1 (G-11): sc-55564 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, epsin 1 (G-11): sc-55564 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Positive signal in WB in mouse transfectedPositive signal in WB in mouse transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-04-08
Rated 5 out of 5 by from Strong signal strength in WB in human transfectedStrong signal strength in WB in human transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-04-05
Rated 5 out of 5 by from Superb immunoperoxidase membrane and cytoplasmicSuperb immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human rectum tissue. -SCBT QC
Date published: 2015-02-27
Rated 5 out of 5 by from Robust signal in WB in JurkatRobust signal in WB in Jurkat, NIH/3T3 and C6 whole cell lysates. -SCBT QC
Date published: 2015-01-09
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epsin 1 抗体 (G-11) is rated 5.0 out of 5 by 4.
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