Date published: 2025-9-8

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Dysadherin 抗体 (G-6): sc-390412

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说明书
  • Dysadherin抗体(G-6)是小鼠单克隆IgG1 (lambda light chain),规格为200 µg/ml
  • 特定于human起源的Dysadherin的C-terminal细胞外结构域内氨基酸115-153之间的表位图谱
  • 推荐用于 human 来源的Dysadherin isoforms 1 and 2 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Dysadherin Antibody (G-6) for WB applications. 的首选辅助检测试剂,这些试剂现与Dysadherin Antibody (G-6) 打包提供(请参阅下面的订购信息)。

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    関連項目

    Dysadherin(包含FXYD结构域的离子转运调节蛋白5)是一种与癌症相关的细胞膜糖蛋白。Dysadherin通过转录后机制下调E-cadherin(上皮细胞间粘附的主要介质)的表达。降低细胞间粘附性有助于癌细胞的转移。Dysadherin存在于脾脏、肺、骨骼肌和睾丸组织中,并定位于人类19号染色体q13.12区域。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Dysadherin 抗体 (G-6) 参考文献:

    1. 胰腺导管腺癌中的Dysadherin过表达反映了肿瘤的侵袭性:与e-cadherin表达的关系。  |  Shimamura, T., et al. 2003. J Clin Oncol. 21: 659-67. PMID: 12586803
    2. O-糖基化异常会抑制癌相关抗原--粘连蛋白的稳定表达,并促进细胞间的粘附。  |  Tsuiji, H., et al. 2003. Glycobiology. 13: 521-7. PMID: 12672699
    3. 胃癌患者中粘连蛋白表达的临床意义。  |  Shimada, Y., et al. 2004. Clin Cancer Res. 10: 2818-23. PMID: 15102690
    4. 舌癌中粘连蛋白表达的预后意义:91 例病例的免疫组化分析。  |  Nakanishi, Y., et al. 2004. Appl Immunohistochem Mol Morphol. 12: 323-8. PMID: 15536331
    5. 宫颈鳞状细胞癌中粘连蛋白表达的预后意义。  |  Wu, D., et al. 2004. Pathol Oncol Res. 10: 212-8. PMID: 15619642
    6. 头颈部鳞状细胞癌中 Dysadherin 的表达:与淋巴管生成的关系及预后意义。  |  Kyzas, PA., et al. 2006. Am J Surg Pathol. 30: 185-93. PMID: 16434892
    7. 趋化因子(C-C 矩阵)配体 2 在人类乳腺癌细胞中介导了粘连不良蛋白的转移效应。  |  Nam, JS., et al. 2006. Cancer Res. 66: 7176-84. PMID: 16849564
    8. 在乳腺癌中,Dysadherin 的表达与侵袭性相关,但与 E-cadherin 无关。  |  Batistatou, A., et al. 2007. Br J Cancer. 96: 1404-8. PMID: 17437014
    9. 头颈部癌症中的粘附分子:粘连蛋白的作用。  |  Giotakis, I., et al. 2011. J BUON. 16: 609-12. PMID: 22331710
    10. 异常调控的Dysadherin和B细胞淋巴瘤2/B细胞淋巴瘤2相关X增强了肝癌干细胞的肿瘤发生和DNA靶向药物耐药性。  |  Jiang, N., et al. 2015. Mol Med Rep. 12: 7239-46. PMID: 26458963

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Dysadherin 抗体 (G-6)

    sc-390412
    200 µg/ml
    RMB2377.00

    Dysadherin (G-6): m-IgG Fc BP-HRP 套装

    sc-540799
    200 µg Ab; 10 µg BP
    RMB2662.00

    Dysadherin (G-6): m-IgG1 BP-HRP 套装

    sc-542375
    200 µg Ab; 20 µg BP
    RMB2662.00

    Dysadherin (G-6) 中和勝肽

    sc-390412 P
    100 µg/0.5 ml
    RMB511.00

    What application is the blocking peptide sc-390412 P appropriate for?

    Asked by: Trav11
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Produced positive Western blot data of DysadherinProduced positive Western blot data of Dysadherin expression in Jurkat and JAR whole cell lysates. -SCBT QC
    Date published: 2014-09-28
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    Dysadherin 抗体 (G-6) is rated 5.0 out of 5 by 1.
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