Date published: 2025-9-8

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Dysadherin 抗体 (D-2): sc-166782

5.0(3)
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说明书
  • Dysadherin抗体(D-2)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长Dysadherin的氨基酸1-178
  • 推荐用于 human 来源的Dysadherin isoform 1 and 2 WB, IP, IF 和 ELISA检测
  • 1 BP-HRP">m-IgG1 BP-HRP是Dysadherin Antibody (D-2) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Dysadherin Antibody (D-2) 打包提供(请参阅下面的订购信息)。

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関連項目

Dysadherin(包含FXYD结构域的离子转运调节蛋白5)是一种与癌症相关的细胞膜糖蛋白。Dysadherin通过转录后机制下调E-cadherin(上皮细胞间粘附的主要介质)的表达。降低细胞间粘附性有助于癌细胞的转移。Dysadherin存在于脾脏、肺、骨骼肌和睾丸组织中,并定位于人类19号染色体q13.12区域。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Dysadherin 抗体 (D-2) 参考文献:

  1. 作为滑膜肉瘤重要预后因素和组织学特征决定因素的 Dysadherin 表达:特别是其与 E-cadherin 表达的反比关系。  |  Izumi, T., et al. 2007. Am J Surg Pathol. 31: 85-94. PMID: 17197923
  2. Dysadherin:癌症进展中的新角色。  |  Nam, JS., et al. 2007. Cancer Lett. 255: 161-9. PMID: 17442482
  3. Dysadherin 可赋予肝癌细胞干样细胞的特性,从而促进肿瘤发生。  |  Park, JR., et al. 2011. J Hepatol. 54: 122-31. PMID: 20952084
  4. 最近发现的粘连不良蛋白在头颈癌 E-粘连蛋白粘附分子下调中的作用。  |  Georgolios, A., et al. 2012. Med Oncol. 29: 1463-7. PMID: 22105147
  5. Dysadherin 的表达通过激活 AKT 促进人类乳腺癌细胞的运动和存活。  |  Lee, YK., et al. 2012. Cancer Sci. 103: 1280-9. PMID: 22494103
  6. 用于治疗具有侵袭性表型的甲状腺癌的Dysadherin特异性药物共轭物。  |  Jang, S., et al. 2017. Oncotarget. 8: 24457-24468. PMID: 28160550
  7. Dysadherin能唤醒机械力,促进结直肠癌的发展。  |  Park, SY., et al. 2022. Theranostics. 12: 4399-4414. PMID: 35673579
  8. 癌症中粘连蛋白的预后价值:系统回顾和荟萃分析。  |  Niinivirta, A., et al. 2022. Front Oncol. 12: 945992. PMID: 36119538
  9. Dysadherin/FAK轴促进结肠癌中单个细胞的迁移。  |  Lee, CJ., et al. 2024. Int J Biol Sci. 20: 2356-2369. PMID: 38725858
  10. 粘连蛋白/MMP9轴改变细胞外基质,加速结直肠癌的进展。  |  Lee, CJ., et al. 2024. Nat Commun. 15: 10422. PMID: 39613801

订购信息

产品名称产品编号规格价格数量收藏夹

Dysadherin 抗体 (D-2)

sc-166782
200 µg/ml
RMB2377.00

Dysadherin (D-2): m-IgG1 BP-HRP 套装

sc-542669
200 µg Ab; 20 µg BP
RMB2662.00

What is the recommended starting dilution for Western blot for sc-166782: Dysadherin (D-2) monoclonal antibody?

Asked by: Germaine
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by from Good WB data with human cellI used it for three weeks with 1:500 in human cell,the result is very wonderful
Date published: 2017-01-07
Rated 5 out of 5 by from Produced positive Western Blot data of DysadherinProduced positive Western Blot data of Dysadherin expression in JAR whole cell lysate. -SCBT QC
Date published: 2015-02-28
Rated 5 out of 5 by from Great Western Blot data of Dysadherin expressionGreat Western Blot data of Dysadherin expression in non-transfected and human Dysadherin transfected 293 whole cell lysates. -SCBT QC
Date published: 2014-08-31
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Dysadherin 抗体 (D-2) is rated 5.0 out of 5 by 3.
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