Date published: 2025-9-8

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DNA-PKCS 抗体 (E-3): sc-390495

4.3(4)
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说明书
  • DNA-PKCS抗体(E-3)是小鼠单克隆IgM κ, 在5篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的DNA-PKCS的C-terminus的氨基酸3493-3511之间
  • 推荐用于 mouse, rat 和 human 来源的DNA-PKcs WB, IP, IF 和 ELISA检测
  • 看 DNA-PKCS (G-12): sc-390849,可查看有标记的 DNA-PKCS 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成DNA-PKCS 抗体 (E-3)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

磷脂酰肌醇激酶(PIK)家族成员分为两个不同的亚组。第一亚组包含PI 3-和PI 4-激酶等蛋白质,第二组包含PIK相关激酶。PIK相关激酶包括Atm、DNA-PKCS和FRAP。这些蛋白质在羧基末端具有同源区,而PI 3-和PI 4-激酶中没有。Atm基因在常染色体隐性遗传性疾病共济失调毛细血管扩张症(AT)中发生突变,其特征是小脑退化(共济失调)和结膜血管扩张(毛细血管扩张症)。AT细胞对电离辐射高度敏感,在介导DNA合成抑制方面受损,并且在p53诱导方面表现出延迟。DNA-PK是一种由大亚基DNA-PKCS和两个小亚基组成的异三聚体DNA结合酶,统称为Ku。DNA-PK的缺失导致DSB修复和V(D)J重组缺陷。FRAP可以在丝氨酸上自磷酸化并与雷帕霉素/FKBP结合。FRAP也是S6激酶的上游调节因子,与p27和p21表达的调节有关。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

DNA-PKCS 抗体 (E-3)

sc-390495
200 µg/ml
RMB2377.00

DNA-PKCS (E-3) 中和勝肽

sc-390495 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-390495 P appropriate for?

Asked by: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Used in IP and got correct bandUsed in IP and got correct band.
Date published: 2015-08-04
Rated 5 out of 5 by from Produced great immunofluorescence nuclearProduced great immunofluorescence nuclear staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-05-02
Rated 4 out of 5 by from Publishable data in WB using human IshikawaPublishable data in WB using human Ishikawa endometrial cancer. -SCBT Publication Review
Date published: 2015-03-17
Rated 4 out of 5 by from Strong bands seen in WB using KStrong bands seen in WB using K-562, MOLT-4, HeLa and CCRF-CEM whole cell lysates. -SCBT QC
Date published: 2015-01-25
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DNA-PK CS 抗体 (E-3) is rated 4.3 out of 5 by 4.
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