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Delta Antibody (E-5) - Western Blotting - Image 356180
Delta 抗体 (E-5): sc-377447. HeLa (A), Hep G2 (B) 和 AMJ2-C8 (C) 全细胞裂解液中 Delta 表达的 Western 印迹分析.
Delta Antibody (E-5) - Western Blotting - Image 356180
Delta 抗体 (E-5): sc-377447. HeLa (A), Hep G2 (B) 和 AMJ2-C8 (C) 全细胞裂解液中 Delta 表达的 Western 印迹分析.
Delta Antibody (E-5) - Western Blotting - Image 284996
Delta 抗体 (E-5): sc-377447. Western 印迹分析非转染: sc-117752 (A) 和人 Delta 转染: sc-171132 (B) 293T 全细胞裂解液中 Delta 的表达.
Delta 抗体 (E-5): sc-377447. HeLa (A), Hep G2 (B) 和 AMJ2-C8 (C) 全细胞裂解液中 Delta 表达的 Western 印迹分析.

Delta 抗体 (E-5): sc-377447

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说明书
  • Delta抗体(E-5)是小鼠单克隆IgG2b (kappa轻链)，规格为200 µg/ml
  • 免疫human物种的Delta的氨基酸459-723
  • 推荐用于 mouse, rat 和 human 来源的Delta WB, IP, IF 和 ELISA检测
  • 2b BP-HRP">m-IgG2b BP-HRP是Delta Antibody (E-5) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Delta Antibody (E-5) 打包提供（请参阅下面的订购信息）。

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    関連項目

    附加Delta抗体，包括Delta-4

    LIN-12/Notch家族的跨膜受体被认为通过调节细胞命运决定在发育中起核心作用。已发现Notch蛋白在人类肿瘤中过度表达或重排。Notch的配体包括Jagged、Jagged-2和Delta。在阻止祖细胞分化为B细胞谱系的同时，Delta促进具有T细胞/NK细胞特征的细胞群的出现。Delta是一种膜蛋白，在原肠胚形成和早期器官发生期间在心脏、胰腺、大脑和肌肉中表达，也在成年心脏和肺中表达。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Delta 抗体 (E-5) 参考文献:

    1. DLL1 介导的 Notch 激活调节小鼠胎儿动脉的内皮特性。  |  Sörensen, I., et al. 2009. Blood. 113: 5680-8. PMID: 19144989
    2. Notch配体Dll1介导了乳腺干细胞与巨噬细胞龛之间的交叉对话。  |  Chakrabarti, R., et al. 2018. Science. 360: PMID: 29773667
    3. 作为细菌性败血症新型诊断生物标志物的宿主衍生δ-Like Canonical Notch 配体 1--组合二次分析的结果。  |  Hildebrand, D., et al. 2019. Front Cell Infect Microbiol. 9: 267. PMID: 31396491
    4. 肝移植患者中的 Delta-like Canonical Notch Ligand 1--一项前瞻性队列研究的二次分析。  |  Decker, SO., et al. 2020. Diagnostics (Basel). 10: PMID: 33142943
    5. 小鼠Notch配体DLL1的活性对体内C终止子标记敏感。  |  Schuster-Gossler, K., et al. 2021. BMC Res Notes. 14: 383. PMID: 34583743
    6. DLL1 在长期血管正常化和癌症免疫疗法中的作用。  |  Wu, Q. and Huang, Y. 2021. Cancer Biol Med. 18: 940-3. PMID: 34708998
    7. Dll1 在胸腺上皮细胞中可作为 Notch1 和 Notch2 的配体发挥作用  |  Hirano, KI., et al. 2022. Front Immunol. 13: 852427. PMID: 35371023
    8. 在食管腺癌中，通过 DLL1 激活 NOTCH 信号是由 APE1 氧化还原依赖性 NF-κB 激活介导的。  |  Chen, L., et al. 2023. Gut. 72: 421-432. PMID: 35750470
    9. Delta-like Canonical Notch 配体 1 可预测外科重症监护患者的败血症和急性肾损伤。  |  Schneck, E., et al. 2022. Sci Rep. 12: 13355. PMID: 35922468
    10. 新型脓毒症生物标志物宿主源性Delta样典型Notch配体1-A的评估：对405名炎症或感染性疾病患者的二次分析。  |  Hölle, T., et al. 2023. Int J Mol Sci. 24: PMID: 37298115

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Delta 抗体 (E-5)

    sc-377447
    200 µg/ml
    		RMB2377.00

    Delta (E-5): m-IgG2b BP-HRP 套装

    sc-548610
    200 µg Ab; 10 µg BP
    		RMB2662.00

    May I ask if this antibody is suitable for immunohistochemistry use on formalin-fixed paraffin embedded blocks? (I noticed the Delta antibody (G-1) is not able to [in one of the feedback questions])

    Asked by: sjaw
    Thank you for your question. This antibody has not been tested for immunohistochemistry on formalin-fixed paraffin embedded tissue sections, so we can not recommend or warranty it for that application. It may, however, work great, we have not tested it. If you have any further questions or would like to try a sample of a Delta antibody, please contact Technical Service by phone, (800)-457-3801 option 2, email <[email protected]>, or by live chat directly on our website, www.scbt.com.
    Answered by: Tech Service
    Date published: 2017-06-22

    What blocking solution should I use with Delta (E-5): sc-377447 monoclonal antibody for Western blot?

    Asked by: jerojero
    Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Produced positive Western blot data of DeltaProduced positive Western blot data of Delta expression in non-transfected and human Delta transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-08-24
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    Delta 抗体 (E-5) is rated 5.0 out of 5 by 1.
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