Date published: 2025-9-6
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Cytokeratin 18 Antibody (C-04) - Western Blotting - Image 389892
细胞角蛋白 18 抗体 (C-04) HRP: sc-51582 HRP. 细胞角蛋白 18 在 MTE1D (A), T24 (B), Hep G2 (C), c4 (D), PC-3 (E) 和 SK-BR-3 (F) 全细胞裂解液中表达的直接 Western 印迹分析.
细胞角蛋白 18 抗体 (C-04) HRP: sc-51582 HRP. 细胞角蛋白 18 在 MTE1D (A), T24 (B), Hep G2 (C), c4 (D), PC-3 (E) 和 SK-BR-3 (F) 全细胞裂解液中表达的直接 Western 印迹分析.

Cytokeratin 18 抗体 (C-04): sc-51582

5.0(10)
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说明书
  • Cytokeratin 18抗体(C-04)是小鼠单克隆IgG1 κ, 在63篇文献中引用，规格为200 µg/ml
  • 针对A-431表皮癌细胞系的细胞骨架制备
  • 抗-Cytokeratin 18 抗体 (C-04) 推荐用于 WB, IP, IF 和 IHC(P)，检测mouse, rat, human, bovine, porcine 和canine 来源的 Cytokeratin 18
  • 抗Cytokeratin 18抗体（C-04）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Cytokeratin 18 (C-04): sc-51582的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 Cytokeratin 18 抗体 (C-04) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Cytokeratin 18 抗体 (C-04) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 Cytokeratin 抗体 包括 Basic Cytokeratin, Cytokeratin 1, Cytokeratin 10, Cytokeratin 12, Cytokeratin 13, Cytokeratin 14, Cytokeratin 15, Cytokeratin 16, Cytokeratin 17和Cytokeratin 18

细胞角蛋白18抗体（C-04）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过应用诸如蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和免疫组织化学等方法检测小鼠、大鼠、人、牛、猪和犬样本中的细胞角蛋白18。抗细胞角蛋白18抗体（C-04）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。细胞角蛋白18（Cytokeratin 18）也称为KRT18，是上皮细胞细胞骨架的重要组成部分，在维持细胞完整性和提供机械支撑方面发挥着关键作用。KRT18主要位于上皮细胞的细胞质中，其定位对于细胞结构和功能至关重要。KRT18定位的破坏会导致细胞稳定性受损，并可能引发包括癌症在内的多种病理状况。KRT18是腺癌和基底细胞癌的重要标志物，因此KRT18成为癌症诊断和研究的重要靶标。此外，KRT18还会经历翻译后修饰，包括特定丝氨酸残基的磷酸化，这对与其他蛋白质（如14-3-3蛋白）的相互作用至关重要，从而影响细胞内角蛋白的组织和分布。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

Cytokeratin 18 抗体 (C-04)

sc-51582
200 µg/ml
RMB2377.00

Cytokeratin 18 (C-04): m-IgG Fc BP-HRP 套装

sc-526753
200 µg Ab; 10 µg BP
RMB2662.00

Cytokeratin 18 (C-04): m-IgG1 BP-HRP 套装

sc-532126
200 µg Ab; 20 µg BP
RMB2662.00

Cytokeratin 18 抗体 (C-04) AC

sc-51582 AC
500 µg/ml, 25% agarose
RMB3129.00

Cytokeratin 18 抗体 (C-04) HRP

sc-51582 HRP
200 µg/ml
RMB2377.00

Cytokeratin 18 抗体 (C-04) FITC

sc-51582 FITC
200 µg/ml
RMB2482.00

Cytokeratin 18 抗体 (C-04) PE

sc-51582 PE
200 µg/ml
RMB2580.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 488

sc-51582 AF488
200 µg/ml
RMB2685.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 546

sc-51582 AF546
200 µg/ml
RMB2685.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 594

sc-51582 AF594
200 µg/ml
RMB2685.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 647

sc-51582 AF647
200 µg/ml
RMB2685.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 680

sc-51582 AF680
200 µg/ml
RMB2685.00

Cytokeratin 18 抗体 (C-04) Alexa Fluor® 790

sc-51582 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 5
Date published: 2017-01-24
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Rated 5 out of 5 by from Works great for IF & WBWorks great for WB and IF in MCF7 breast cancer cells.
Date published: 2021-03-01
Rated 5 out of 5 by from Good antibodyWorked well on normal epithelial cells, IF staining.
Date published: 2018-07-24
Rated 5 out of 5 by from antibodyOnly for human tissues, animal tissue positive performance is not obvious
Date published: 2018-03-07
Rated 5 out of 5 by from Works well for Rat taste bud markerMy search for a good taste bud marker for rat ended with this antibody. Works well at 1:100.
Date published: 2018-02-28
Rated 5 out of 5 by from Excellent antibodyThere are may Cytokeratin 18 clones to choose from, but the (C-04) clone is one of the best. Very popular choice for WB and IF as indicated by the numerous recent product citations.
Date published: 2017-01-05
Rated 5 out of 5 by from IF publication using langerhans cell sarcomaIF publication using langerhans cell sarcoma of human origin -SCBT Publication Review
Date published: 2015-04-13
Rated 5 out of 5 by from Positive western blot analysis of CytokeratinPositive western blot analysis of Cytokeratin 18 expression in T24 whole cell lysate. -SCBT QC
Date published: 2015-03-31
Rated 5 out of 5 by from Publication with immunocytochemistry withPublication with immunocytochemistry with mouse testes samples -SCBT Publication Review
Date published: 2015-03-15
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Cytokeratin 18 抗体 (C-04) is rated 5.0 out of 5 by 10.
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