Date published: 2025-9-6

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Cytokeratin 10 抗体 (LH2): sc-53252

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说明书
  • Cytokeratin 10抗体(LH2)是小鼠单克隆IgG1 κ, 在23篇文献中引用,规格为200 µg/ml
  • 针对human牛皮癣患者皮肤提取物
  • 抗-Cytokeratin 10 抗体 (LH2) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 Cytokeratin 10
  • 抗Cytokeratin 10抗体(LH2)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Cytokeratin 10 (LH2): sc-53252免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 Cytokeratin 10 抗体 (LH2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Cytokeratin 10 抗体 (LH2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

细胞角蛋白10抗体(LH2)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学等方法检测小鼠、大鼠和人类样本中的细胞角蛋白10。抗细胞角蛋白10抗体(LH2)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。细胞角蛋白10与上皮细胞中的角蛋白1形成异四聚体,有助于细胞骨架结构和机械弹性。细胞角蛋白10主要位于表皮的上皮层,包括角质层,在角质形成细胞分化中起着至关重要的作用。细胞角蛋白10的表达有助于抵御环境压力,并有助于皮肤屏障功能。细胞角蛋白10是鳞状细胞癌的标志物,有助于恶性肿瘤的鉴别和诊断。细胞角蛋白10单克隆抗体(LH2)使研究人员能够深入了解上皮细胞的行为和病理,因此这种抗体对于基础研究和临床研究至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Cytokeratin 10 抗体 (LH2) 参考文献:

  1. [评估人类皮肤鳞状细胞癌的恶性程度与细胞角蛋白-10积累之间的关系]。  |  Osiecka, BJ., et al. 2001. Przegl Lek. 58: 435-8. PMID: 11603178
  2. 金黄色葡萄球菌凝集因子 B(ClfB)促进人类 I 型细胞角蛋白 10 的粘附:对鼻腔定植的影响。  |  O'Brien, LM., et al. 2002. Cell Microbiol. 4: 759-70. PMID: 12427098
  3. 凝集因子 B 是金黄色葡萄球菌的一种纤维蛋白原结合型 MSCRAMM(微生物表面成分识别粘附基质分子)粘附素,也能与 I 型细胞角蛋白 10 的尾部区域结合。  |  Walsh, EJ., et al. 2004. J Biol Chem. 279: 50691-9. PMID: 15385531
  4. 细胞角蛋白 10 阴性巢状模式可将克隆性脂溢性角化病与页状鲍温氏病明确区分开来。  |  Böer-Auer, A., et al. 2012. J Cutan Pathol. 39: 225-33. PMID: 22236073
  5. 麻风分枝杆菌的 HSP 65 与宿主角蛋白的细胞角蛋白 10 之间的分子拟态;在麻风病发病机制中的作用。  |  Singh, I., et al. 2012. Cell Immunol. 278: 63-75. PMID: 23121977
  6. Kallikrein 介导的细胞角蛋白 10 降解是水痘带状疱疹病毒在皮肤中传播所必需的。  |  Tommasi, C., et al. 2020. J Invest Dermatol. 140: 774-784.e11. PMID: 31626786
  7. 癌症中细胞角蛋白 10 (CK10) 的表达:对 11,021 例肿瘤进行的组织芯片研究。  |  Uhlig, R., et al. 2022. Ann Diagn Pathol. 60: 152029. PMID: 36029589
  8. 细胞角蛋白 10、13 和内卷曲素的表达作为低分期子宫颈鳞状细胞癌的预后因素。  |  van Bommel, PF., et al. 1994. Cancer. 74: 2314-20. PMID: 7522949
  9. 评估皮肤鳞状细胞癌中层粘蛋白和细胞角蛋白-10的表达。  |  Osiecka, BJ., et al. 1997. Folia Histochem Cytobiol. 35: 121-2. PMID: 9151104
  10. 将非放射性原位杂交作为一种常规方法,确定细胞角蛋白 10 mRNA 在人体表皮中的位置。  |  Meinhold-Heerlein, I., et al. 1998. Arch Dermatol Res. 290: 286-8. PMID: 9681682

订购信息

产品名称产品编号规格价格数量收藏夹

Cytokeratin 10 抗体 (LH2)

sc-53252
200 µg/ml
RMB2377.00

Cytokeratin 10 (LH2): m-IgG Fc BP-HRP 套装

sc-528561
200 µg Ab; 10 µg BP
RMB2662.00

Cytokeratin 10 (LH2): m-IgGκ BP-HRP 套装

sc-520964
200 µg Ab, 40 µg BP
RMB2662.00

Cytokeratin 10 (LH2): m-IgG1 BP-HRP 套装

sc-542996
200 µg Ab; 20 µg BP
RMB2662.00

Cytokeratin 10 抗体 (LH2) AC

sc-53252 AC
500 µg/ml, 25% agarose
RMB3129.00

Cytokeratin 10 抗体 (LH2) HRP

sc-53252 HRP
200 µg/ml
RMB2377.00

Cytokeratin 10 抗体 (LH2) FITC

sc-53252 FITC
200 µg/ml
RMB2482.00

Cytokeratin 10 抗体 (LH2) PE

sc-53252 PE
200 µg/ml
RMB2580.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 488

sc-53252 AF488
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 546

sc-53252 AF546
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 594

sc-53252 AF594
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 647

sc-53252 AF647
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 680

sc-53252 AF680
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (LH2) Alexa Fluor® 790

sc-53252 AF790
200 µg/ml
RMB2685.00

Can Cytokeratin 10 (LH2): sc-53252 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Cytokeratin 10 (LH2): sc-53252 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2023-11-13
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Rated 5 out of 5 by from superbwe applicate it into ICC , and we got the positive result
Date published: 2017-07-15
Rated 5 out of 5 by from Worked wellThe antibody worked well on mice tissue using IF and IHC
Date published: 2017-03-22
Rated 5 out of 5 by from Produced publishable IF data in HumanThis antibody has several citations in the literature for the use in IF on paraffin-embedded human skin tissue
Date published: 2017-01-26
Rated 5 out of 5 by from The antibody specificity is quite good.Immunohistochemical stain quickly,the purpose stripe of western blot is very clear.in a word,I'm very pleased with it.
Date published: 2017-01-12
Rated 5 out of 5 by from Good quality antibody for human paraffin samplesGood quality antibody for human paraffin samples. Specific and sensitive -SCBT QC
Date published: 2015-03-26
Rated 5 out of 5 by from Single strong band at correct mw in C32 nonSingle strong band at correct mw in C32 non-reducing buffer, not boiled whole cell lysate. -SCBT QC
Date published: 2015-03-19
Rated 5 out of 5 by from Clean WB blot with single strong band in HeLaClean WB blot with single strong band in HeLa. -SCBT QC
Date published: 2014-09-25
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Cytokeratin 10 抗体 (LH2) is rated 5.0 out of 5 by 7.
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