Date published: 2025-9-6

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Cytokeratin 10 抗体 (RKSE60): sc-23877

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说明书
  • Cytokeratin 10抗体(RKSE60)是小鼠单克隆IgG1 κ, 在37篇文献中引用,规格为200 µg/ml
  • 针对来自human表皮细胞角蛋白
  • 抗-Cytokeratin 10 抗体 (RKSE60) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 Cytokeratin 10; 也和以下物种反应,包括: canine
  • 抗Cytokeratin 10抗体(RKSE60)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Cytokeratin 10 (RKSE60): sc-23877免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Cytokeratin 10 抗体 (RKSE60) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Cytokeratin 10 抗体 (RKSE60) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

细胞角蛋白10抗体(RKSE60)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学等方法检测小鼠、大鼠和人类样本中的细胞角蛋白10。抗细胞角蛋白10抗体(RKSE60)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。细胞角蛋白10(Cytokeratin 10)也称为KRT10,与角蛋白1形成异四聚体,由上皮细胞细胞骨架中的两种I型和两种II型角蛋白组成。细胞角蛋白10主要位于表皮的上层,包括角质层,并维持上皮组织的结构完整性和机械弹性。细胞角蛋白10是角质形成细胞分化的标志物,有助于确定鳞状细胞癌的特征。了解细胞角蛋白10的定位和功能有助于深入了解上皮细胞分化以及各种皮肤病和癌症的病理变化。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Cytokeratin 10 抗体 (RKSE60) 参考文献:

  1. 使用链特异性抗体研究皮肤上皮囊肿和一些不常见的囊性肿瘤中细胞角蛋白的表达。  |  Broekaert, D., et al. 1990. Arch Dermatol Res. 282: 383-91. PMID: 1701984
  2. 细胞角蛋白 10 和细胞角蛋白 19:治愈性切除术后肝细胞癌患者预后不良的预测标志物。  |  Yang, XR., et al. 2008. Clin Cancer Res. 14: 3850-9. PMID: 18559605
  3. 细胞角蛋白 10 阴性巢状模式可将克隆性脂溢性角化病与页状鲍温氏病明确区分开来。  |  Böer-Auer, A., et al. 2012. J Cutan Pathol. 39: 225-33. PMID: 22236073
  4. 在福尔马林固定, 石蜡包埋组织中识别表皮分化相关角蛋白的新型单克隆抗体。外阴癌中角蛋白 10 的表达。  |  Ivanyi, D., et al. 1989. J Pathol. 159: 7-12. PMID: 2478685
  5. Kallikrein 介导的细胞角蛋白 10 降解是水痘带状疱疹病毒在皮肤中传播所必需的。  |  Tommasi, C., et al. 2020. J Invest Dermatol. 140: 774-784.e11. PMID: 31626786
  6. 阿兰托帕松是金黄色葡萄球菌粘附纤维蛋白原、Loricrin 和细胞角蛋白 10 的泛抑制剂。  |  Prencipe, F., et al. 2022. Microbiol Spectr. 10: e0117521. PMID: 35647689
  7. 癌症中细胞角蛋白 10 (CK10) 的表达:对 11,021 例肿瘤进行的组织芯片研究。  |  Uhlig, R., et al. 2022. Ann Diagn Pathol. 60: 152029. PMID: 36029589
  8. 评估健康人和前列腺癌患者细胞角蛋白 8 和 18 片段的新型肿瘤标记物。  |  Silén, A., et al. 1994. Prostate. 24: 326-32. PMID: 7516071
  9. 用于定量检测健康人和癌症患者血清中细胞角蛋白 8 和 18 片段的新型 IRMA 和 ELISA。  |  Silén, A., et al. 1995. Scand J Clin Lab Invest. 55: 153-61. PMID: 7545308
  10. 正常和(恶性前)头颈部上皮细胞角蛋白的表达:综述。  |  van der Velden, LA., et al. 1993. Head Neck. 15: 133-46. PMID: 7680025
  11. 肺癌患者血清和组织中细胞角蛋白 19(cyfra 21-1)片段的分布。  |  Quillien, V., et al. 1995. Anticancer Res. 15: 2857-63. PMID: 8669879
  12. 肝细胞中细胞角蛋白的表达, 纤维组织和微妙功能。  |  Marceau, N. and Loranger, A. 1995. Biochem Cell Biol. 73: 619-25. PMID: 8714681

订购信息

产品名称产品编号规格价格数量收藏夹

Cytokeratin 10 抗体 (RKSE60)

sc-23877
200 µg/ml
RMB2377.00

Cytokeratin 10 (RKSE60): m-IgG Fc BP-HRP 套装

sc-526623
200 µg Ab; 10 µg BP
RMB2662.00

Cytokeratin 10 (RKSE60): m-IgG1 BP-HRP 套装

sc-531996
200 µg Ab; 20 µg BP
RMB2662.00

Cytokeratin 10 抗体 (RKSE60) AC

sc-23877 AC
500 µg/ml, 25% agarose
RMB3129.00

Cytokeratin 10 抗体 (RKSE60) HRP

sc-23877 HRP
200 µg/ml
RMB2377.00

Cytokeratin 10 抗体 (RKSE60) FITC

sc-23877 FITC
200 µg/ml
RMB2482.00

Cytokeratin 10 抗体 (RKSE60) PE

sc-23877 PE
200 µg/ml
RMB2580.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 488

sc-23877 AF488
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 546

sc-23877 AF546
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 594

sc-23877 AF594
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 647

sc-23877 AF647
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 680

sc-23877 AF680
200 µg/ml
RMB2685.00

Cytokeratin 10 抗体 (RKSE60) Alexa Fluor® 790

sc-23877 AF790
200 µg/ml
RMB2685.00

Hi, Can you please response regarding what is RKSE60? Thank you

Asked by: Sudheer
Thank you for your question. RKSE60 is the name of the clone producing this antibody.
Answered by: Tech Support Europe
Date published: 2024-12-03

I work primarily with monkey samples. Do you know if this antibody will cross-react?

Asked by: Cweed
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 13
Date published: 2017-01-09
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Rated 5 out of 5 by from Works really well for flow cytometryThis antibody on AF647 worked really well for me on a flow cytometry panel. Would highly recommend.
Date published: 2022-04-21
Rated 5 out of 5 by from Good on FFPEI used this antibody on formalin-fixed paraffin-embedded human epithelium. It worked well at a dilution of 1:30 for 15 minutes.
Date published: 2017-08-10
Rated 5 out of 5 by from Good Cytokeratin 10 antibodyGood, published antibody that produces strong signal in WB, IP, and staining (IHC/IF). Recommended for mouse, rat, human, and canine Cytokeratin 10 detection.
Date published: 2017-01-16
Rated 5 out of 5 by from Nice quality results in IF with mouse endometrialNice quality results in IF with mouse endometrial epithelial cells -SCBT Publication Review
Date published: 2015-02-08
Rated 5 out of 5 by from Works well in Western with human HaCaT samplesWorks well in Western with human HaCaT samples -SCBT Publication Review
Date published: 2015-01-04
Rated 5 out of 5 by from Strong staining in IHC with formalin fixedStrong staining in IHC with formalin fixed, paraffin-embedded human vulva/anal skin tissue -SCBT QC
Date published: 2014-03-18
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Cytokeratin 10 抗体 (RKSE60) is rated 5.0 out of 5 by 6.
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