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creatine kinase-M 抗体 (MM-64): sc-69878

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说明书
  • creatine kinase-M抗体(MM-64)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的creatine kinase-M
  • 推荐用于 mouse, rat 和 human 来源的creatine kinase-M WB 和 IP检测
  • m-IgG Fc BP-HRP是creatine kinase-M Antibody (MM-64) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与creatine kinase-M Antibody (MM-64) 搭配使用(请参阅下面的订购信息)。

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関連項目

肌酸激酶(CKs)是一个大的同工酶家族,它们在亚细胞区室内调节ATP的水平。通过在肌酸和腺嘌呤核苷酸之间转移磷酸盐,它们在有波动能量需求的位点提供ATP。肌酸激酶为驱动许多细胞系统的正常功能提供了必要的磷酸水解能量,这些细胞系统包括肌肉、发电细胞、视网膜感光细胞、脑细胞、肾脏、盐腺、子宫肌层、胎盘、胰腺、胸腺、甲状腺、肠上皮细胞、内皮细胞、软骨和骨细胞、巨噬细胞、血小板以及肿瘤和癌细胞。人细胞质肌酸激酶-B,也被称为CK-B和BCK,是肌酸激酶的一种由381个氨基酸组成的脑组织特异性亚型。人细胞质肌酸激酶-M(CK-M,MCK)是肌酸激酶的一种肌肉组织特异性亚型。人细胞质肌酸激酶-Mi(Mi-CK,MtCK)是肌酸激酶的一种由416个氨基酸组成的线粒体特异性亚型。细胞溶质肌酸激酶在Ca2+泵的能量调节和维持Ca2+稳态中起着重要作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

creatine kinase-M 抗体 (MM-64) 参考文献:

  1. 对患有扩张型心肌病的Rac1转基因小鼠进行蛋白质组学分析,发现肌酸激酶M链蛋白含量增加。  |  Buscemi, N., et al. 2003. Mol Cell Biochem. 251: 145-51. PMID: 14575316
  2. 利用同源和非同源载体在胚胎干细胞中靶向肌酸激酶M基因。  |  van Deursen, J. and Wieringa, B. 1992. Nucleic Acids Res. 20: 3815-20. PMID: 1508665
  3. CK-MM自身抗体:患病率、免疫复合物以及对CK清除的影响。  |  Warren, GL., et al. 2006. Muscle Nerve. 34: 335-46. PMID: 16810680
  4. CK-MM和ACE基因型以及肌酸激酶对运动的生理反应预测。  |  Heled, Y., et al. 2007. J Appl Physiol (1985). 103: 504-10. PMID: 17478608
  5. CK-MM基因多态性不会影响剧烈偏心运动后的血液CK活性水平。  |  Yamin, C., et al. 2010. Int J Sports Med. 31: 213-7. PMID: 20157874
  6. 通过连续靶向小鼠胚胎干细胞中的一种肌酸激酶M等位基因来调节基因活性。  |  van Deursen, J., et al. 1991. Nucleic Acids Res. 19: 2637-43. PMID: 2041741
  7. 杜氏肌肉萎缩症患者的神经支配和收缩培养肌纤维中CK-MM的积累受到损害。  |  Askanas, V., et al. 1987. Life Sci. 41: 927-33. PMID: 3613854
  8. 心脏组织中肌酸激酶M和B同工酶组成的定量酶法:考虑用于发育和成年大鼠心脏的研究。  |  Dowell, RT. and Fu, MC. 1995. Methods Find Exp Clin Pharmacol. 17: 29-37. PMID: 7623518
  9. 同时自动测量血清总CK和CK-MM同工酶比值。  |  Uji, Y., et al. 1994. J Clin Lab Anal. 8: 273-6. PMID: 7807281
  10. 肌酸激酶M线蛋白及其与肌球蛋白和肌球蛋白片段相互作用的物理化学研究。  |  Mani, RS. and Kay, CM. 1976. Biochim Biophys Acta. 453: 391-9. PMID: 793621

订购信息

产品名称产品编号规格价格数量收藏夹

creatine kinase-M 抗体 (MM-64)

sc-69878
200 µg/ml
RMB2377.00

creatine kinase-M (MM-64): m-IgG Fc BP-HRP 套装

sc-539254
200 µg Ab; 10 µg BP
RMB2662.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with creatine kinase-M (MM-64): sc-69878?

Asked by: Cweed
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-06-06
Rated 4 out of 5 by from Strong bands seen in WB using human skeletalStrong bands seen in WB using human skeletal muscle and human heart tissue extracts. -SCBT QC
Date published: 2015-04-05
Rated 5 out of 5 by from WB publishable data with helaWB publishable data with hela - SCBT Publication Review
Date published: 2013-11-07
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creatine kinase-M 抗体 (MM-64) is rated 4.3 out of 5 by 3.
  • y_2025, m_8, d_30, h_9
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