Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

Cdc25C 抗体 (F-5): sc-55513

5.0(4)
寫評論提問

说明书
  • Cdc25C抗体(F-5)是小鼠单克隆IgG1 κ, 在8篇文献中引用,规格为200 µg/ml
  • 免疫human来源Cdc25C位于N-terminus 的1-150氨基酸
  • 推荐用于 human 来源的Cdc25C WB, IP, IF 和 ELISA检测
  • 看 Cdc25C (H-6): sc-13138,可查看有标记的 Cdc25C 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Cdc25C Antibody (F-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Cdc25C Antibody (F-5) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

细胞周期事件受细胞周期蛋白依赖性激酶(Cdks)的顺序激活和失活的调节,包括Cdk2和Cdc2。Cdk2与cyclin E和cyclin A的复合物对于DNA复制的开始和进展似乎是必要的,而Cdc2激酶与cyclin A或cyclin B的复合物对于细胞分裂的启动是必需的。Wee 1已被鉴定为一种蛋白激酶,通过介导抑制Cdc2 p34的酪氨酸磷酸化来抑制进入有丝分裂。相反,蛋白质磷酸酶Cdc25家族的成员通过去磷酸化Cdc2 p34上的调节性酪氨酸和可能的苏氨酸残基而作为有丝分裂激活剂发挥作用。Cdc25基因家族至少包含三个成员,在其最保守的羧基端序列中共享约40%的同源性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Cdc25C 抗体 (F-5) 参考文献:

  1. 减数分裂 G2/M 过渡期的 Cdc25C 活性调控  |  Perdiguero, E. and Nebreda, AR. 2004. Cell Cycle. 3: 733-7. PMID: 15136768
  2. 丝胶蛋白 A 可刺激 cdc25C 的功能,促进进入有丝分裂。  |  Telles, E., et al. 2011. Cell Cycle. 10: 776-82. PMID: 21325883
  3. 依赖细胞周期的 Cdc25C 磷酸酶通过调节凋亡信号调节激酶 1 决定细胞存活。  |  Cho, YC., et al. 2015. Cell Death Differ. 22: 1605-17. PMID: 25633196
  4. Mdm2 可促进 Cdc25C 蛋白降解,推迟细胞周期进入 G2/M 阶段。  |  Giono, LE., et al. 2017. Oncogene. 36: 6762-6773. PMID: 28806397
  5. CDC25C 在肺腺癌中的预后意义:对 TCGA 数据的分析。  |  Xia, Z., et al. 2019. Cancer Genet. 233-234: 67-74. PMID: 31109596
  6. CDC25B 和 CDC25C 在非黑色素瘤皮肤癌中的过表达可抑制细胞死亡。  |  Al-Matouq, J., et al. 2019. Mol Carcinog. 58: 1691-1700. PMID: 31237025
  7. 利用生物信息学分析鉴定 CDC25C 作为肝细胞癌的潜在生物标记物  |  Xun, R., et al. 2020. Technol Cancer Res Treat. 19: 1533033820967474. PMID: 33111630
  8. 体外转染肿瘤相关抗原 Cdc25C 的 DC2.4 细胞的抗肝癌作用  |  Li, CM., et al. 2022. Curr Med Sci. 42: 491-497. PMID: 35292875
  9. miR-142-3p/CDC25C 轴在调节非小细胞肺癌自噬中的调控作用。  |  Meng, J., et al. 2024. Transl Lung Cancer Res. 13: 552-572. PMID: 38601452
  10. KIF22 通过调节 CDC25C/CDK1/cyclinB1 通路促进多发性骨髓瘤的进展。  |  Zhai, M., et al. 2024. J Cancer Res Clin Oncol. 150: 239. PMID: 38713252

订购信息

产品名称产品编号规格价格数量收藏夹

Cdc25C 抗体 (F-5)

sc-55513
200 µg/ml
RMB2377.00

Cdc25C (F-5): m-IgG Fc BP-HRP 套装

sc-537059
200 µg Ab; 10 µg BP
RMB2662.00

Cdc25C (F-5): m-IgGκ BP-HRP 套装

sc-534245
200 µg Ab; 40 µg BP
RMB2662.00

Cdc25C (F-5): m-IgG1 BP-HRP 套装

sc-544980
200 µg Ab; 20 µg BP
RMB2662.00

Is there a free sample size available for CdC25 A and C antibodies

Asked by: Viji
Thank you for your interest in our antibody sample program . For information on how to receive a sample please email [email protected].
Answered by: BlakeJ
Date published: 2024-11-22

What is the recommended starting dilution for Western blot for sc-55513: Cdc25C (F-5) monoclonal antibody?

Asked by: AbPolly
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
  • y_2025, m_8, d_30, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_55513, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 112ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Good publishable results by Western BlotGood publishable results by Western Blot obtained using mouse embryo cortex and A7 melanoma samples. -SCBT Publication Review
Date published: 2015-04-16
Rated 5 out of 5 by from Using immunofluorescenceUsing immunofluorescence, good staining observed for mouse embryo cortex and A7 melanoma samples. -SCBT Publication Review
Date published: 2015-03-27
Rated 5 out of 5 by from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the Cdc25C protein via Western Blot analysis. -SCBT QC
Date published: 2015-01-19
Rated 5 out of 5 by from Robust signal obtained at appropriate molecularRobust signal obtained at appropriate molecular weight via Western Blot using K-562 and Raji whole cell lysates. -SCBT QC
Date published: 2014-02-05
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_55513, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
Cdc25C 抗体 (F-5) is rated 5.0 out of 5 by 4.
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_55513, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 97ms
  • REVIEWS, PRODUCT