Date published: 2025-9-7

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CD79A 抗体 (ZL7-4): sc-13529

3.0(1)
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说明书
  • CD79A 抗体 ZL7-4 是小鼠单克隆 IgG1, 在1篇文献中引用,提供 200 µg/ml
  • 与Daudi IgM复合物结合
  • 推荐用于 human 来源的CD79A IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 CD79A (HM47): sc-20064,可查看有标记的 CD79A 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成CD79A 抗体 (ZL7-4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

CD79(也称为Igα/Igβ)是一种由α链(称为CD79A或MB-1)和β链(称为CD79B或B29)组成的异二聚体。B细胞抗原受体复合物(BCR)是由CD79与膜免疫球蛋白(如IgM或IgD)结合形成的。IgM和IgD膜免疫球蛋白在CD79结合的作用下实现表面表达和抗原呈递功能。CD79A和CD79B的细胞质尾部均含有ITAM(免疫受体酪氨酸基激活)基序,它通过结合和激活酪氨酸激酶来启动BCR信号反应。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD79A 抗体 (ZL7-4) 参考文献:

  1. 人 B-CLL 细胞中 CD79a(Ig alpha)和 CD79b(Ig beta)转录物的交替剪接。  |  Alfarano, A., et al. 1999. Curr Top Microbiol Immunol. 246: 241-6; discussion 247-8. PMID: 10396062
  2. CD79a(+)T细胞淋巴细胞淋巴瘤并发朗格汉斯细胞组织细胞增生症。  |  Li, S. and Borowitz, MJ. 2001. Arch Pathol Lab Med. 125: 958-60. PMID: 11419987
  3. 典型霍奇金淋巴瘤中 CD79a 表达的临床病理学意义。  |  Sakatani, A., et al. 2020. J Clin Exp Hematop. 60: 78-86. PMID: 32641598
  4. CD79a 可促进小儿 B 细胞前体急性淋巴细胞白血病的中枢神经系统浸润和白血病移植。  |  Lenk, L., et al. 2021. Commun Biol. 4: 73. PMID: 33452446
  5. 复合 CD79A/CD40 共刺激内结构域可增强 CD19CAR-T 细胞的增殖和存活。  |  Julamanee, J., et al. 2021. Mol Ther. 29: 2677-2690. PMID: 33940156
  6. 细胞质CD79a是CD19 CAR-T疗法后B淋巴细胞白血病随访的有望生物标记物。  |  Chen, M., et al. 2022. Leuk Lymphoma. 63: 426-434. PMID: 34672246
  7. CD79A 和 CD79B 通过 B 细胞受体表面表达支持 IgM+ B 细胞健壮的机制  |  Huse, K., et al. 2022. J Immunol. 209: 2042-2053. PMID: 36426942
  8. 在发育中的小鼠肾小球中,Cd79a 驱动的条件性 mTOR 激活导致膀胱生成的机制。  |  Tran Nguyen Truc, L., et al. 2023. Sci Rep. 13: 508. PMID: 36627370
  9. B 细胞受体信号及其他:正常和恶性 B 细胞中 Igα (CD79a)/Igβ (CD79b) 的作用。  |  Tkachenko, A., et al. 2023. Int J Mol Sci. 25: PMID: 38203179
  10. 氟西汀成功治疗了一名因 19 号染色体节段性单亲断裂而导致 CD79a 缺失的患者的颅内肠道病毒 E18 感染。  |  Yu, L., et al. 2024. J Clin Immunol. 44: 137. PMID: 38805163

订购信息

产品名称产品编号规格价格数量收藏夹

CD79A 抗体 (ZL7-4)

sc-13529
200 µg/ml
RMB2377.00

CD79A 抗体 (ZL7-4) FITC

sc-13529 FITC
200 µg/ml
RMB2482.00

CD79A 抗体 (ZL7-4) PE

sc-13529 PE
200 µg/ml
RMB2580.00

Does this specifically recognize the extra cellular domain of CD79a?

Asked by: Tom K
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2023-11-20

How can CD79A (ZL7-4): sc-13529 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: AbPolly
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-13529 PE) or fluoroscein (sc-13529 FITC).
Answered by: Technical Support
Date published: 2017-02-27
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Rated 3 out of 5 by from Produced good FCM data for human peripheralProduced good FCM data for human peripheral blood leukocytes. -SCBT QC
Date published: 2014-02-19
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CD79A 抗体 (ZL7-4) is rated 3.0 out of 5 by 1.
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