Date published: 2025-9-6

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CD79A 抗体 (HM57): sc-53208

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说明书
  • CD79A抗体(HM57)是小鼠单克隆IgG1 κ, 在12篇文献中引用,规格为200 µg/ml
  • 与human来源的mb-1 cDNA序列的202-216氨基酸对应的合成肽
  • CD79A 抗体 (HM57) 推荐用于WB, IP, IF 和 IHC(P) ,检测 mouse, rat, human 和 来源的CD79A; 也和以下物种反应,包括: 和 Porcine, Bovine, Canine, Chicken, Equine, Guinea Pig, Monkey, Rabbit
  • 抗CD79A抗体(HM57)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CD79A (HM57): sc-53208免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 CD79A 抗体 (HM57) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CD79A 抗体 (HM57) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CD79A抗体(HM57)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学检测小鼠、大鼠和人类来源的CD79A蛋白。抗CD79A抗体(HM57)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。CD79A,也称为MB-1,是B细胞抗原受体复合物的重要组成部分,在B细胞活化和免疫反应中发挥着至关重要的作用。CD79A蛋白位于B细胞表面,与CD79B形成异二聚体,促进与膜免疫球蛋白(如IgM和IgD)的结合。这种相互作用对于这些免疫球蛋白的有效表面表达至关重要,使B细胞能够呈现抗原并启动免疫反应。此外,CD79A和CD79B的细胞质尾部含有免疫受体酪氨酸基激活基序(ITAM),在抗原结合时触发下游信号通路,最终导致B细胞活化和增殖。CD79A能够调节这些过程,这凸显了它在适应性免疫系统中的重要性,使CD79A(HM57)单克隆抗体成为研究B细胞生物学和相关免疫功能的研究人员的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD79A 抗体 (HM57) 参考文献:

  1. 流式细胞仪检测 T 细胞急性淋巴细胞白血病中 CD79a 的表达。  |  Lai, R., et al. 2000. Am J Clin Pathol. 113: 823-30. PMID: 10874883
  2. 免疫组织化学检测前体 T 细胞淋巴母细胞淋巴瘤/白血病中 CD79a 的表达。  |  Hashimoto, M., et al. 2002. J Pathol. 197: 341-7. PMID: 12115880
  3. CD79a 在肿瘤性和正常髓系前体及巨核细胞中以抗体克隆依赖性方式异质性表达。  |  Bhargava, P., et al. 2007. Am J Clin Pathol. 128: 306-13. PMID: 17638667
  4. 狗死后检查发现垂体中存在 CD3+ 和 CD79a+ 淋巴细胞  |  Blomqvist, MA., et al. 2020. J Comp Pathol. 176: 116-121. PMID: 32359623
  5. 受损的抗原结合和信号传导会干扰双特异性CD19和CD79a嵌合抗原受体功能。  |  Leung, I., et al. 2023. Blood Adv. 7: 2718-2730. PMID: 36469024
  6. CD79A/CD40 costimulatory domain 的 T 细胞增殖和记忆基因特征的丰富可增强 CD19CAR-T 细胞的功能。  |  Ung, S., et al. 2022. Front Immunol. 13: 1064339. PMID: 36505428
  7. 基于 CD79A、DKK1 和 VEGFC 预测肺腺癌的预后和免疫疗法反应。  |  Zhang, Q., et al. 2023. Heliyon. 9: e18503. PMID: 37534013
  8. 扩展 CD79A 基因突变和难治性双螺旋杆菌感染的临床表型。  |  Sil, A., et al. 2024. J Clin Immunol. 44: 187. PMID: 39215847
  9. 人 B 细胞中 CD79a(Ig-alpha/mb-1)和 CD79b(Ig-beta/B29)RNA 转录物的交替剪接。  |  Hashimoto, S., et al. 1995. Mol Immunol. 32: 651-9. PMID: 7643857
  10. 淋巴母细胞淋巴瘤共同表达 CD79a (JCB117) 和 CD3。  |  Pilozzi, E., et al. 1998. J Pathol. 186: 140-3. PMID: 9924428

订购信息

产品名称产品编号规格价格数量收藏夹

CD79A 抗体 (HM57)

sc-53208
200 µg/ml
RMB2377.00

CD79A (HM57): m-IgG Fc BP-HRP 套装

sc-526779
200 µg Ab; 10 µg BP
RMB2662.00

CD79A (HM57): m-IgG1 BP-HRP 套装

sc-532152
200 µg Ab; 20 µg BP
RMB2662.00

CD79A 抗体 (HM57) AC

sc-53208 AC
500 µg/ml, 25% agarose
RMB3129.00

CD79A 抗体 (HM57) HRP

sc-53208 HRP
200 µg/ml
RMB2377.00

CD79A 抗体 (HM57) FITC

sc-53208 FITC
200 µg/ml
RMB2482.00

CD79A 抗体 (HM57) PE

sc-53208 PE
200 µg/ml
RMB2580.00

CD79A 抗体 (HM57) Alexa Fluor® 488

sc-53208 AF488
200 µg/ml
RMB2685.00

CD79A 抗体 (HM57) Alexa Fluor® 546

sc-53208 AF546
200 µg/ml
RMB2685.00

CD79A 抗体 (HM57) Alexa Fluor® 594

sc-53208 AF594
200 µg/ml
RMB2685.00

CD79A 抗体 (HM57) Alexa Fluor® 647

sc-53208 AF647
200 µg/ml
RMB2685.00

CD79A 抗体 (HM57) Alexa Fluor® 680

sc-53208 AF680
200 µg/ml
RMB2685.00

CD79A 抗体 (HM57) Alexa Fluor® 790

sc-53208 AF790
200 µg/ml
RMB2685.00

Hello, are there any issues with using CD79 (HM57) mouse monoclonal antibody on turtle samples?

Asked by: Marcele
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. please call us toll-free at (800) 457-3801 option 2, e-mail <[email protected]>, or use the live chat on our website.
Answered by: Sen Li
Date published: 2021-09-01

Are there any issues with using sc-53208: CD79A (HM57) mouse monoclonal primary antibody on mouse samples?

Asked by: jenniferc
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-53208 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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