Date published: 2025-9-6

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CD1D 抗体 (3H649): sc-70571

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说明书
  • CD1D抗体(3H649)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 免疫human物种的CD1D
  • 推荐用于 human 来源的CD1D WB, IP, IF 和 IHC(P)检测
  • 看 CD1D (C3D5): sc-19632,可查看有标记的 CD1D 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 CD1D 抗体 (3H649) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CD1D 抗体 (3H649) 组合成套装提供。 (请参阅下面的订购信息)。

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    関連項目

    CD1D抗体(3H649)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学等方法检测人类样本中的CD1D。CD1D是CD1多基因家族的重要成员,该家族编码五种形式的CD1 T细胞表面糖蛋白,通过向T淋巴细胞呈递脂质抗原在免疫系统中发挥重要作用。CD1D主要位于人体肠上皮细胞表面,以两种形式存在:一种为β-2微球蛋白非依赖性非糖基化形式,另一种为β-2微球蛋白依赖性糖基化形式。这些细胞上的CD1D表达对于调节肠道免疫反应至关重要,会影响CD1限制性T细胞的成熟和激活。人类CD1D基因位于1q23.1号染色体上,编码一种335个氨基酸的蛋白质,对正常T细胞发育至关重要。抗CD1D抗体(3H649)是研究免疫反应、T细胞成熟以及脂质抗原在人类健康和疾病中的作用的研究人员的重要工具。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    CD1D 抗体 (3H649) 参考文献:

    1. CD1d在正常和病态B细胞中的作用和调节。  |  Chaudhry, MS. and Karadimitris, A. 2014. J Immunol. 193: 4761-8. PMID: 25381357
    2. CD1d限制的II型NKT细胞对内源性疏水肽的反应。  |  Nishioka, Y., et al. 2018. Front Immunol. 9: 548. PMID: 29599785
    3. CD1d和MR1限制的T细胞在哮喘中的作用。  |  Iwamura, C. and Nakayama, T. 2018. Front Immunol. 9: 1942. PMID: 30210497
    4. CD1d和MR1限制性T细胞在肝脏中的作用。  |  Huang, W., et al. 2018. Front Immunol. 9: 2424. PMID: 30425710
    5. CD1d缺陷限制了腹膜巨噬细胞的耐受性。  |  Basri, F., et al. 2021. BMB Rep. 54: 209-214. PMID: 33407995
    6. CD1d表达区分具有明确造血潜能的CDX4+造血中胚层。  |  Philip Creamer, J., et al. 2022. Stem Cell Res. 62: 102808. PMID: 35569347
    7. 可被Sortase A裂解的CD1d将鞘氨醇脂质鉴定为CD1d相关脂质的主要类别。  |  Rudolph, M., et al. 2022. Front Immunol. 13: 897873. PMID: 35874748
    8. CD1d限制的NKT细胞在炎症性皮肤病中的作用和治疗潜力。  |  Lee, SW., et al. 2022. Front Immunol. 13: 979370. PMID: 36119077
    9. 先进的组学技术揭示了CD1d介导的脂质抗原向iNKT细胞的呈递。  |  Morris, I., et al. 2023. Biochim Biophys Acta Mol Cell Biol Lipids. 1868: 159292. PMID: 36773690
    10. CD1d依赖性自然杀伤T细胞通过白介素-17A介导高血压和血管损伤。  |  Xiao, X., et al. 2023. J Am Heart Assoc. 12: e029179. PMID: 37382154

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CD1D 抗体 (3H649)

    sc-70571
    200 µg/ml
    $316.00

    CD1D (3H649): m-IgG Fc BP-HRP 套装

    sc-539295
    200 µg Ab; 10 µg BP
    $354.00

    CD1D (3H649): m-IgG1 BP-HRP 套装

    sc-541387
    200 µg Ab; 20 µg BP
    $354.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with CD1D (3H649): sc-70571?

    Asked by: DefinitelyNotMatt
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
    Date published: 2014-06-23
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    CD1D 抗体 (3H649) is rated 3.0 out of 5 by 1.
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