Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

CD13 抗体 (B-F10): sc-65292

4.0(4)
寫評論提問

说明书
  • CD13抗体(B-F10)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 针对KG-1a细胞系
  • 推荐用于 human 来源的CD13 WB, IP 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是CD13 Antibody (B-F10) for WB applications. 的首选辅助检测试剂,这些试剂现与CD13 Antibody (B-F10) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

CD13,又称氨基肽酶N,是一种II型跨膜糖蛋白,在大多数髓系来源的细胞上表达,包括单核细胞、嗜碱性粒细胞、嗜酸性粒细胞、中性粒细胞和髓系白血病。CD13也存在于某些上皮细胞、成纤维细胞和破骨细胞上。CD13作为锌结合金属蛋白酶,在消化中发挥作用,并可能在一些调节肽(如脑啡肽)的失活中发挥作用。CD13可能通过增强癌细胞的侵袭能力和转移行为而在癌细胞的侵袭中发挥作用。CD13的活性可以通过使用特定的抑制剂来灭活,这些抑制剂可以诱导CD13阳性癌细胞的凋亡。碱性成纤维细胞生长因子(bFGF)的表达通过激活髓系和上皮CD13启动子,上调人黑色素瘤细胞中CD13的表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD13 抗体 (B-F10) 参考文献:

  1. 氨基肽酶N(APN/CD13)抑制剂研发进展。  |  Xu, W. and Li, Q. 2005. Curr Med Chem Anticancer Agents. 5: 281-301. PMID: 15992355
  2. 氨基肽酶N(APN/CD13)抑制剂研究最新进展。  |  Zhang, X., et al. 2011. Curr Med Chem. 18: 5011-21. PMID: 22050749
  3. 一种抑制Treg细胞抑制功能的抗人CD13单克隆抗体。  |  Zhang, K., et al. 2013. Monoclon Antib Immunodiagn Immunother. 32: 16-20. PMID: 23600500
  4. 沉默 FLI 或靶向 CD13/ANPEP 会导致 BRAF 抑制剂抗性介质 EPHA2 的去磷酸化,并诱导黑色素瘤细胞生长停滞或凋亡。  |  Azimi, A., et al. 2017. Cell Death Dis. 8: e3029. PMID: 29048432
  5. CD13作为组织因子诱导的小细胞肺癌肿瘤血管梗死的靶标。  |  Schmidt, LH., et al. 2017. Lung Cancer. 113: 121-127. PMID: 29110838
  6. DNA修复激酶ATM调节CD13的表达和细胞迁移。  |  Stevenson, LK., et al. 2024. Front Cell Dev Biol. 12: 1359105. PMID: 38933336
  7. 嗜血杆菌入侵素AipA与CD13相互作用,引发Src激酶信号,促进感染。  |  Lind, MCH., et al. 2024. mBio. 15: e0156124. PMID: 39324816
  8. 鉴定出LRP1+CD13+人骨膜干细胞,这些细胞需要LRP1才能进行骨修复。  |  Jeong, Y., et al. 2024. JCI Insight. 9: PMID: 39405183
  9. 二肽基肽酶IV(CD 26)和氨基肽酶N(CD 13)催化N端细胞因子序列的细胞因子和肽的水解。  |  Hoffmann, T., et al. 1993. FEBS Lett. 336: 61-4. PMID: 7903256
  10. 髓样抗原CD13、CD14和/或CD33仅限于某些淋巴肿瘤。  |  Nakase, K., et al. 1996. Am J Clin Pathol. 105: 761-8. PMID: 8659452

订购信息

产品名称产品编号规格价格数量收藏夹

CD13 抗体 (B-F10)

sc-65292
200 µg/ml
RMB2377.00

CD13 (B-F10): m-IgG Fc BP-HRP 套装

sc-539170
200 µg Ab; 10 µg BP
RMB2662.00

CD13 (B-F10): m-IgG1 BP-HRP 套装

sc-541308
200 µg Ab; 20 µg BP
RMB2662.00

CD13 抗体 (B-F10) FITC

sc-65292 FITC
200 µg/ml
RMB2482.00

CD13 抗体 (B-F10) PE

sc-65292 PE
200 µg/ml
RMB2580.00

How can CD13 (B-F10): sc-65292 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: jenniferc
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-65292 PE) or fluoroscein (sc-65292 FITC).
Answered by: Technical Support
Date published: 2017-02-25
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_65292, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 101ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-06-12
Rated 4 out of 5 by from Produced clear indirect FCM data for humanProduced clear indirect FCM data for human peripheral blood leukocytes stained with CD13 . -SCBT QC
Date published: 2015-06-01
Rated 4 out of 5 by from Strong band seen in WB using CCDStrong band seen in WB using CCD-1064Sk whole cell lysate. -SCBT QC
Date published: 2015-04-22
Rated 4 out of 5 by from Great FCM data of THPGreat FCM data of THP-1 cells. -SCBT QC
Date published: 2013-03-22
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65292, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
CD13 抗体 (B-F10) is rated 4.0 out of 5 by 4.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65292, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 104ms
  • REVIEWS, PRODUCT