Date published: 2025-9-9

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cathepsin E 抗体 (C-7): sc-166501

5.0(2)
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说明书
  • cathepsin E抗体(C-7)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的cathepsin E的N-terminus附近的氨基酸57-75之间
  • 推荐用于 mouse, rat 和 human 来源的cathepsin E WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 cathepsin E 抗体 (C-7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与cathepsin E 抗体 (C-7) 组合成套装提供。 (请参阅下面的订购信息)。

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    関連項目

    蛋白水解酶的组织蛋白酶家族包含几种不同的蛋白酶类。半胱氨酸蛋白酶类包括组织蛋白酶B、L、H、K、S和O。天冬氨酸蛋白酶类由组织蛋白酶D和E组成。Cath-epsin G属于丝氨酸蛋白酶类。大多数组织蛋白酶都是溶酶体的,每一种都参与细胞代谢,参与肽生物合成和蛋白质降解等各种事件。组织蛋白酶E是一种非溶酶体、细胞内的蛋白酶。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    cathepsin E 抗体 (C-7) 参考文献:

    1. Cathepsin E缺乏与特应性皮炎的发展有关。  |  Tsukuba, T., et al. 2003. J Biochem. 134: 893-902. PMID: 14769879
    2. 人类组织蛋白酶E三级结构的建模。  |  Chou, KC. 2005. Biochem Biophys Res Commun. 331: 56-60. PMID: 15845357
    3. 组织蛋白酶E缺陷小鼠对细菌感染的易感性增加,与多种细胞表面Toll样受体的表达减少有关。  |  Tsukuba, T., et al. 2006. J Biochem. 140: 57-66. PMID: 16877769
    4. 组织蛋白酶E对树突状细胞和巨噬细胞的性质和功能的差异调节。  |  Kakehashi, H., et al. 2007. J Immunol. 179: 5728-37. PMID: 17947645
    5. 使用新型蛋白酶激活荧光探针对小鼠体内Cathepsin E阳性肿瘤进行分子成像。  |  Abd-Elgaliel, WR., et al. 2011. Mol Biosyst. 7: 3207-3213. PMID: 21935563
    6. 胰腺癌相关的组织蛋白酶 E 作为药物激活剂。  |  Abd-Elgaliel, WR., et al. 2013. J Control Release. 167: 221-7. PMID: 23422726
    7. 巴雷特食管腺癌患者组织中组织蛋白酶E的高表达,但血液中无高表达。  |  Fisher, OM., et al. 2015. Ann Surg Oncol. 22: 2431-8. PMID: 25348778
    8. 组织蛋白酶E的过度表达通过降解N-钙粘蛋白,干扰P19胚胎畸胎瘤细胞的神经元分化。  |  Harada, Y., et al. 2017. Cell Mol Neurobiol. 37: 437-443. PMID: 27116544
    9. 一种酶激活聚集诱导发光探针:通过特异性组织蛋白酶E对胰腺癌进行术中病理荧光诊断。  |  Zhu, Z., et al. 2022. Adv Mater. 34: e2107444. PMID: 34693566
    10. 阿尔茨海默型痴呆患者大脑中组织蛋白酶E的免疫组织化学研究。  |  Bernstein, HG. and Wiederanders, B. 1994. Brain Res. 667: 287-90. PMID: 7697369

    订购信息

    产品名称产品编号规格价格数量收藏夹

    cathepsin E 抗体 (C-7)

    sc-166501
    200 µg/ml
    $316.00

    cathepsin E (C-7): m-IgG Fc BP-HRP 套装

    sc-540112
    200 µg Ab; 10 µg BP
    $354.00

    cathepsin E (C-7): m-IgG1 BP-HRP 套装

    sc-541910
    200 µg Ab; 20 µg BP
    $354.00

    cathepsin E (C-7) 中和勝肽

    sc-166501 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-166501 P appropriate for?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from WB: Great signal in human cathepsin E transfectedWB: Great signal in human cathepsin E transfected 293T whole cell lysates. -SCBT QC
    Date published: 2015-04-18
    Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
    Date published: 2015-02-12
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    cathepsin E 抗体 (C-7) is rated 5.0 out of 5 by 2.
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