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CAR Antibody (A-10) - Western Blotting - Image 300526
CAR 抗体 (A-10): sc-365836. HeLa 全细胞裂解液 (A) 和小鼠肝组织提取物 (B) 中 CAR 表达的 Western 印迹分析.
CAR Antibody (A-10) - Western Blotting - Image 300526
CAR 抗体 (A-10): sc-365836. HeLa 全细胞裂解液 (A) 和小鼠肝组织提取物 (B) 中 CAR 表达的 Western 印迹分析.
CAR Antibody (A-10) - Western Blotting - Image 354780
CAR 抗体 (A-10): sc-365836. F9 全细胞裂解液中 CAR 表达的 Western 印迹分析.
CAR Antibody (A-10) - Western Blotting - Image 145508
CAR 抗体 (A-10): sc-365836. 非转染: sc-117752 (A) 和人 CAR 转染: sc-159755 (B) 293T 全细胞裂解液中 CAR 表达的 Western 印迹分析.
CAR 抗体 (A-10): sc-365836. HeLa 全细胞裂解液 (A) 和小鼠肝组织提取物 (B) 中 CAR 表达的 Western 印迹分析.

CAR 抗体 (A-10): sc-365836

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说明书
  • CAR 抗体 A-10 是小鼠单克隆 IgG2a，提供 200 µg/ml
  • 免疫human物种的CAR的氨基酸1-300
  • 推荐用于 mouse, rat 和 human 来源的CAR WB, IP, IF 和 ELISA检测
  • 看 CAR (E-1): sc-373791，可查看有标记的 CAR 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 2a BP-HRP">m-IgG2a BP-HRP和m-IgGκ BP-HRP是CAR Antibody (A-10) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与CAR Antibody (A-10) 打包提供（请参阅下面的订购信息）。

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    描述
    基因信息
    蛋白序列
    说明书与实验方案
    研究信息

    関連項目

    柯萨奇和腺病毒受体（CAR）通过特异性蛋白相互作用结合各种腺病毒来介导病毒感染。病毒旋钮结构域与CAR的细胞外氨基末端结构域（称为D1）之间具有高亲和力。单独的D1结构域足以在转染细胞中结合旋钮。确定CAR和腺病毒之间的特异性相互作用对于进一步开发使用病毒载体的基因治疗是必不可少的。CAR在许多人类和小鼠细胞类型中表达。然而，低水平表达CAR的细胞不能被腺病毒感染。在某些细胞类型中避免这一问题的可能方法是补充CAR或修饰Ad旋钮以结合其他受体。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    CAR 抗体 (A-10) 参考文献:

    1. 临床膀胱癌中 Integrin alpha(v) 和柯萨奇腺病毒受体的表达。  |  Sachs, MD., et al. 2002. Urology. 60: 531-6. PMID: 12350512
    2. 柯萨奇病毒和腺病毒受体表达的缺失与侵袭性膀胱癌的特征有关。  |  Matsumoto, K., et al. 2005. Urology. 66: 441-6. PMID: 16040097
    3. 柯萨奇病毒和腺病毒受体与微管结合，在细胞迁移中发挥作用。  |  Fok, PT., et al. 2007. J Biol Chem. 282: 7512-21. PMID: 17210569
    4. 表达柯萨奇病毒和腺病毒受体可降低小鼠肿瘤细胞的肺转移潜能。  |  Yamashita, M., et al. 2007. Int J Cancer. 121: 1690-6. PMID: 17546646
    5. 柯萨奇病毒和腺病毒受体的缺失导致胃癌进展。  |  Anders, M., et al. 2009. Br J Cancer. 100: 352-9. PMID: 19142187
    6. 柯萨奇病毒和腺病毒受体的表达可区分治疗诱导的细胞衰老中的过渡癌状态。  |  Wu, PC., et al. 2010. Cell Death Dis. 1: e70. PMID: 21364674
    7. 柯萨奇病毒和腺病毒受体是乳腺癌雌激素作用的靶点和介质。  |  Vindrieux, D., et al. 2011. Endocr Relat Cancer. 18: 311-21. PMID: 21389059
    8. 柯萨奇病毒和腺病毒受体在人类肺癌中的表达。  |  Chen, Z., et al. 2013. Tumour Biol. 34: 17-24. PMID: 23307165
    9. 柯萨奇病毒和腺病毒受体是口腔鳞状细胞生存和生长的关键调节因子。  |  Saito, K., et al. 2014. Oncogene. 33: 1274-86. PMID: 23503462
    10. CAR：粘附和炎症的关键调节因子。  |  Ortiz-Zapater, E., et al. 2017. Int J Biochem Cell Biol. 89: 1-5. PMID: 28545889

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CAR 抗体 (A-10)

    sc-365836
    200 µg/ml
    		RMB2377.00

    CAR (A-10): m-IgG Fc BP-HRP 套装

    sc-537845
    200 µg Ab; 10 µg BP
    		RMB2662.00

    CAR (A-10): m-IgGκ BP-HRP 套装

    sc-535268
    200 µg Ab; 40 µg BP
    		RMB2662.00

    CAR (A-10): m-IgG2a BP-HRP 套装

    sc-548130
    200 µg Ab; 10 µg BP
    		RMB2662.00

    I need to use an antibody to detect the protein in samples of equine origin. Do you know if sc-365836: CAR (A-10) mouse monoclonal antibody will work?

    Asked by: Professor Griffin
    Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
    Answered by: Technical Support
    Date published: 2017-03-06

    Do you have trial size or free sample available?

    Asked by: jiz007
    Thank you for your inquiry Please contact our Technical Service Department to request a free 10 µg sample if you would like to test the antibody in your intended research application. Please call Technical Support toll-free at 1800-457-3801, email [email protected], or contact us by live chat.
    Answered by: Santa Cruz TS
    Date published: 2016-12-13
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    Rated 5 out of 5 by from Satisfactory Western Blot data of CAR expressionSatisfactory Western Blot data of CAR expression in HeLa whole cell lysate and mouse liver tissue extract . -SCBT QC
    Date published: 2015-04-19
    Rated 5 out of 5 by from Nice Western Blot data of CAR expression in nonNice Western Blot data of CAR expression in non-transfected and human CAR transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-04-14
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    CAR 抗体 (A-10) is rated 5.0 out of 5 by 2.
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