Date published: 2025-9-8
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)

C5b-9 抗体 (2A1): sc-66190

4.0(3)
寫評論提問

说明书
  • C5b-9 抗体 2A1 是小鼠单克隆 IgG1 κ，C5b-9抗体, 在12篇文献中引用，规格为200 µg/ml
  • 针对纯化的C5b-9 rat 起源
  • C5b-9 抗体 (2A1) 推荐用于 WB 和 IF，检测mouse 和rat 来源的 a neoantigen of the C5b-9 complex
  • 抗C5b-9抗体（2A1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取C5b-9 (2A1): sc-66190的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是C5b-9 Antibody (2A1) for WB applications. 的首选辅助检测试剂，这些试剂现与C5b-9 Antibody (2A1) 打包提供（请参阅下面的订购信息）。

快捷链接

相关产品
描述
说明书与实验方案
研究信息

関連項目

附加Complement Pathway Protein抗体，包括C3, C3a / α, C3 α, C3aR, C3d, C4, C4 α, C4 β, C5b-9, C5 β, C5L2, C6, C8 γ和C9

C5b-9 抗体（2A1）是一种小鼠单克隆 IgG1 kappa 轻链抗体，可通过免疫印迹（WB）和免疫荧光（IF）检测小鼠和大鼠来源的 C5b-9 蛋白。抗 C5b-9 抗体 (2A1) 有非共轭型和多种共轭型，包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。C5b-9 蛋白是补体系统的重要组成部分，在补体蛋白 C5、C6、C7、C8 和 C9 的活化过程中形成，共同促进免疫反应。C5b-9 蛋白在免疫系统中扮演着双重角色；C5b-9 蛋白在通过形成膜攻击复合物促进细胞溶解的同时，还能在某些情况下诱导细胞周期活化和存活，例如在少突胶质细胞中，C5b-9 蛋白能通过磷脂酶 3- 激酶信号调节 Caspase-8 的处理，从而防止 FAS 介导的细胞凋亡。在多发性硬化症等疾病中，C5b-9 蛋白在急性期可能会加剧炎症，而在慢性期则具有保护作用。了解 C5b-9 蛋白的功能动态对于阐明其在各种病症中的影响和治疗策略至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

C5b-9 抗体 (2A1)

sc-66190
200 µg/ml
RMB2377.00

C5b-9 (2A1): m-IgG Fc BP-HRP 套装

sc-526976
200 µg Ab; 10 µg BP
RMB2662.00

C5b-9 (2A1): m-IgG1 BP-HRP 套装

sc-532349
200 µg Ab; 20 µg BP
RMB2662.00

C5b-9 抗体 (2A1) AC

sc-66190 AC
500 µg/ml, 25% agarose
RMB3129.00

C5b-9 抗体 (2A1) HRP

sc-66190 HRP
200 µg/ml
RMB2377.00

C5b-9 抗体 (2A1) FITC

sc-66190 FITC
200 µg/ml
RMB2482.00

C5b-9 抗体 (2A1) PE

sc-66190 PE
200 µg/ml
RMB2580.00

C5b-9 抗体 (2A1) Alexa Fluor® 488

sc-66190 AF488
200 µg/ml
RMB2685.00

C5b-9 抗体 (2A1) Alexa Fluor® 546

sc-66190 AF546
200 µg/ml
RMB2685.00

C5b-9 抗体 (2A1) Alexa Fluor® 594

sc-66190 AF594
200 µg/ml
RMB2685.00

C5b-9 抗体 (2A1) Alexa Fluor® 647

sc-66190 AF647
200 µg/ml
RMB2685.00

C5b-9 抗体 (2A1) Alexa Fluor® 680

sc-66190 AF680
200 µg/ml
RMB2685.00

C5b-9 抗体 (2A1) Alexa Fluor® 790

sc-66190 AF790
200 µg/ml
RMB2685.00

Molecular weight, WB without reference？

Asked by: lancet
Thank you for your question. It would be helpful if you could call 021 60936350 or email us, [email protected], allowing for a more interactive discussion of this and other related questions.
Answered by: Ling Chen
Date published: 2024-12-04

Are there any issues with using sc-66190: C5b-9 (2A1) mouse monoclonal primary antibody on human samples?For flow cytometer？

Asked by: Jingchao
Thank you for your question. C5b-9 Antibody (2A1): sc-66190 is recommended for detection of a neoantigen of the C5b-9 complex of mouse and rat origin by WB and IF. It is not recommended for detection of human C5b-9. The antibody has not been tested for flow cytometry and currently there is no data indicating whether or not the antibody is suitable for this application.
Answered by: Tech Support Europe
Date published: 2019-05-27

Are there any issues with using sc-66190: C5b-9 (2A1) mouse monoclonal primary antibody on mouse samples?

Asked by: TinTin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-66190 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
  • y_2025, m_9, d_4, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_3
  • loc_zh_CN, sid_66190, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 115ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Workded as expected.Worked well for IF staining in the in vitro bacterial killing experiment.
Date published: 2019-04-24
Rated 4 out of 5 by from 结果符合预期以小鼠作为模式动物，流式检测补体系统在损伤的肝细胞表面的激活。 选择荧光直标抗体后，检测结果较好。 对于诱导损伤的肝细胞Necrosis-1和-2，均能检测到显著的C5b-9结合。
Date published: 2019-02-12
Rated 4 out of 5 by from Works well for IF applicationsWorks well for IF applications, positive in guinea pig nerve samples. -SCBT Publication Review
Date published: 2015-02-03
  • y_2025, m_9, d_4, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_66190, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
C5b-9 抗体 (2A1) is rated 4.0 out of 5 by 3.
  • y_2025, m_9, d_4, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_66190, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 128ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。