Date published: 2025-9-8

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beta Arrestin 1/2 抗体 (21-B1): sc-53781

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说明书
  • beta Arrestin 1/2 抗体 21-B1 是小鼠单克隆 IgG1, 在5篇文献中引用,提供 200 µg/ml
  • 针对β-arrestin 1,来自human来源
  • 推荐用于 mouse, rat 和 human 来源的β-Arrestin 1 and β-Arrestin 2 WB, IP 和 IHC(P)检测
  • 看 β-Arrestin-2 (B-4): sc-365445,可查看有标记的 beta Arrestin 1/2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成beta Arrestin 1/2 抗体 (21-B1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

β-Arrestin-1/2 抗体 (21-B1) 是一种小鼠单克隆 IgG1 抗体,可检测小鼠、大鼠、人和牛等多个物种的 β-Arrestin-1 和 β-Arrestin-2 。抗β-阿restin-1/2 抗体(21-B1)是针对与人β-阿restin-1 的丝氨酸 86 至苏氨酸 98 周围区域相对应的合成肽提出的,可用于免疫印迹(WB)、免疫沉淀(IP)和石蜡包埋切片免疫组织化学(IHCP)等应用的检测。β-Arrestin 蛋白是 G 蛋白偶联受体(GPCR)信号传导的关键调节因子,在介导受体脱敏和内化的同时,还能启动独立于 G 蛋白的替代信号传导途径。从结构上看,β-阿restin-1 和 β-Arrestin-2 均由两个不同的结构域组成:一个 N 端结构域和一个 C 端结构域,这两个结构域共同形成一个双叶结构,对于它们与磷酸化 GPCR 和各种信号蛋白的相互作用至关重要。翻译后修饰,包括磷酸化和泛素化,通过调节细胞内的相互作用、稳定性和定位,在调节 β-Arrestins 的功能方面起着至关重要的作用。这些修饰对于精确控制受体贩运和信号终止至关重要,从而影响激素信号转导、神经传递和免疫反应等多种生理过程。β-阿restin-1和β-阿restin-2主要在脾脏和神经元组织中表达,是维持细胞平衡和促进对细胞外刺激做出适当反应不可或缺的成分。此外,β-阿restin 与各种激酶和适配蛋白相互作用,进一步强调了它们在细胞内信号网络中的重要性。β-阿restin-1/2(21-B1)单克隆抗体性能稳定可靠,是研究人员研究β-阿restin 介导的信号通路的结构和功能动态的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

beta Arrestin 1/2 抗体 (21-B1)

sc-53781
200 µg/ml
RMB2377.00

Hi, do you know the epitope recognized by this Ab?

Asked by: qsdfsfqsdf
Thank you for your question. sc-53781 was raised against the full length raised against β-arrestin 1 of human origin. The exact epitope was not mapped yet.
Answered by: Tech Support Europe
Date published: 2021-12-16

I am using β-Arrestin-1/2 (21-B1): sc-53781 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Trav11
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Nice western blot resultsWe used this antibody for a western blot experiment and got nice dark bands at the correct molecular weight
Date published: 2017-01-19
Rated 4 out of 5 by from Clear band obtained by Western Blot in SupT1Clear band obtained by Western Blot in SupT1-L23 cell line and in CD4+ lymphocytes
Date published: 2015-10-21
Rated 4 out of 5 by from Published IP data with human HeLa and HEKPublished IP data with human HeLa and HEK 293 cells - SCBT Publication Review
Date published: 2015-04-02
Rated 4 out of 5 by from DecentDecent, clear band detected in WB in PC-12, SK-N-MC and RAW 264.7 whole cell lysates. -SCBT QC
Date published: 2015-02-28
Rated 4 out of 5 by from Produced robust immunoperoxidase cytoplasmicProduced robust immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human cerebellum tissue. -SCBT QC
Date published: 2013-06-01
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beta Arrestin 1/2 抗体 (21-B1) is rated 4.2 out of 5 by 5.
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