Date published: 2025-9-6

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Bcr 抗体 (7C6): sc-103

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说明书
  • Bcr抗体(7C6)是小鼠单克隆IgG2a κ, 在17篇文献中引用,规格为200 µg/ml
  • 针对氨基酸686-698的图谱,在Bcr的内部区域,human起源
  • 推荐用于 mouse, rat 和 human 来源的Bcr/Abl p210 fusion protein in CML, but not Bcr/Abl p190, WB, IP, IF 和 IHC(P)检测
  • 看 Bcr (B-12): sc-28375,可查看有标记的 Bcr 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Bcr 抗体 (7C6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Bcr基因定位于染色体22号,最初是基于它与染色体9号上的c-Abl原癌基因融合而被发现的,这种融合在慢性髓性白血病(CML)患者中有90-95%的发生率。Bcr基因编码Breakpoint cluster region蛋白(Bcr)。这种转座的结果是产生Bcr/c-Abl mRNA,编码活化的c-Abl蛋白激酶。Bcr基因已被证明编码一种针对Ras相关GTP结合蛋白Rac 1 p21的GTP酶激活蛋白(GAP)。虽然有人推测Bcr蛋白也可能刺激Rac 2 p21 GTP酶的活性,但它对Ras p21或Rho p21 GTP酶没有影响。有趣的是,Bcr的GAP结构域定位于CML中仍留在染色体22号(费城染色体)上的区域之外。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Bcr 抗体 (7C6)

sc-103
200 µg/ml
RMB2377.00

Can Bcr (7C6): sc-103 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Professor Griffin
Thank you for your question. Yes, Bcr (7C6): sc-103 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for WB and co-IP on Sf9 cells - SCBT Publication Review
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Bcr抗体 (7C6) is rated 5.0 out of 5 by 5.
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