Date published: 2026-11-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

Bax 抗体 (SPM336): sc-65532

5.0(4)
寫評論提問
说明书
  • Bax抗体(SPM336)是小鼠单克隆IgG1 κ, 在8篇文献中引用,规格为200 µg/ml
  • 针对与human的Bax的3-16个氨基酸对应的合成肽
  • 推荐用于 mouse, rat, human 和 primate 来源的Bax WB, IP, IF, IHC(P) 和 FCM检测
  • 看 Bax (B-9): sc-7480,可查看有标记的 Bax 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP是Bax Antibody (SPM336) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与Bax Antibody (SPM336) 搭配使用(请参阅下面的订购信息)。
Gene Editing Promo Banner

快捷链接

関連項目

Bax 抗体 (SPM336) 是一种小鼠单克隆 IgG1 抗体,可通过各种应用检测小鼠、大鼠、人类和灵长类动物样本中的 Bax,包括免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组化 (IHCP) 和流式细胞术 (FCM)。Bax 是一种重要的促凋亡蛋白,在调节细胞凋亡或程序性细胞死亡方面发挥着重要作用,而细胞凋亡可维持细胞平衡并清除受损或不需要的细胞。Bax 和抗凋亡的 Bcl-2 之间的平衡对决定细胞的命运至关重要;Bax 水平的增加可促进细胞凋亡,尤其是在对压力信号或生长因子撤消做出反应时。Bax 主要定位于线粒体外膜,Bax 可促进细胞色素 c 的释放,这是细胞凋亡途径中的关键步骤。Bax 表达或功能的改变可导致各种疾病,包括癌症,而逃避凋亡是癌症的一个特征。Bax (SPM336) 抗体是研究人员研究细胞凋亡机制以及各种生物环境中促凋亡和抗凋亡信号的复杂平衡的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

含汞:所有HRP偶联物(包括组合装)均含有硫柳汞,这是一种汞化合物。请勿丢弃在垃圾中。应按照当地、州和联邦法规,将其作为危险化学品废弃物进行处置。

下载硫柳汞安全数据表(SDS)

Bax 抗体 (SPM336) 参考文献:

  1. Bax 易位到线粒体后,线粒体膜电位迅速丧失。  |  Smaili, SS., et al. 2001. Cell Death Differ. 8: 909-20. PMID: 11526446
  2. Bax 和 Bak 可独立促进线粒体释放细胞色素 C。  |  Degenhardt, K., et al. 2002. J Biol Chem. 277: 14127-34. PMID: 11836241
  3. Bax诱导的拟南芥细胞死亡是通过依赖和不依赖活性氧的过程介导的。  |  Baek, D., et al. 2004. Plant Mol Biol. 56: 15-27. PMID: 15604726
  4. Bax 激活机制中的构象异质性。  |  Barnes, CA., et al. 2017. Structure. 25: 1310-1316.e3. PMID: 28712810
  5. Parkin促进蛋白酶体降解被误调的BAX。  |  Cakir, Z., et al. 2017. J Cell Sci. 130: 2903-2913. PMID: 28760928
  6. 人VAMP3抑制或负向调节酵母菌中Bax诱导的细胞凋亡。  |  Akintade, DD. and Chaudhuri, B. 2021. Biomedicines. 9: PMID: 33478086
  7. CHO细胞中有效的CRISPR/Cas9介导的BAX基因消减以抑制细胞凋亡并提高重组蛋白的产量。  |  Rahimi, A., et al. 2023. Iran J Biotechnol. 21: e3388. PMID: 37228627
  8. 裂殖酵母中 Bax 和 Bak 诱导的细胞死亡。  |  Jürgensmeier, JM., et al. 1997. Mol Biol Cell. 8: 325-39. PMID: 9190211
  9. bax(而非 bcl-2)影响人类胰腺癌的预后。  |  Friess, H., et al. 1998. Gut. 43: 414-21. PMID: 9863489

订购信息

产品名称产品编号规格价格数量收藏夹

Bax 抗体 (SPM336)

sc-65532
200 µg/ml
CNY2422.00

Bax (SPM336): m-IgG Fc BP-HRP 套装

sc-539184
200 µg Ab; 10 µg BP
CNY2715.00

Are there any issues with using sc-65532: Bax (SPM336) mouse monoclonal primary antibody on mouse samples?

Asked by: TinTin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-65532 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
  • y_2026, m_11, d_7, h_7CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.50
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_65532, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 99ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by JM from Works well with many different human cellWorks well with many different human cell lines: atrophic endometrium, hyperplasia endometrium, carcinoma endometrium and normal endometrium. -SCBT Publication Review
Date published: 2015-04-28
Rated 5 out of 5 by SF from Strong Western bands achieved on mouse BaxStrong Western bands achieved on mouse Bax transfected 293T, and HuT 78 whole cell lysates. -SCBT QC
Date published: 2015-04-22
Rated 5 out of 5 by LR from Positive bands in Western Blot upon analysisPositive bands in Western Blot upon analysis of SW480, HuT 78, Ramos, BJAB and MDA-MB-231 whole cell lysates. -SCBT QC
Date published: 2015-01-04
Rated 5 out of 5 by ET from Publishable Western blot results used onPublishable Western blot results used on human 22rv1 and PC3 cells. -SCBT Publication Review
Date published: 2014-05-09
  • y_2026, m_11, d_6, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.50
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65532, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
Bax抗体 (SPM336) is rated 5.0 out of 5 by 4.
  • y_2026, m_11, d_6, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.50
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65532, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 77ms
  • REVIEWS, PRODUCT