Date published: 2025-9-7

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ATAD3B 抗体 (A-8): sc-514615

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说明书
  • ATAD3B抗体(A-8)是小鼠单克隆IgM κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的ATAD3B的C-terminus附近的氨基酸598-615之间
  • 推荐用于 human 来源的ATAD3B isoforms 1 and 3 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取ATAD3B (A-8): sc-514615免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成ATAD3B 抗体 (A-8)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

ATAD3B抗体(A-8)是一种小鼠单克隆IgM抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人类来源的ATAD3B。抗ATAD3B抗体(A-8)以非结合形式提供,可在各种实验环境中进行多种应用。ATAD3B是AAA ATP酶家族的一员,其特点是高度保守的AAA结构域对ATP酶活性至关重要。ATAD3B在线粒体功能中起着重要作用,特别是在稳定核体方面,核体对于维持线粒体DNA的完整性和组织性至关重要。ATAD3B的功能对于细胞器生物发生和囊泡介导的蛋白质运输等细胞过程至关重要,而这些过程对于细胞稳态和能量产生至关重要。ATAD3B与少突胶质细胞瘤的转化途径和化学敏感性有关,这凸显了其在癌症生物学中的潜在相关性。ATAD3B的三个同源物通过可变剪接产生,在细胞内发挥不同的功能。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ATAD3B 抗体 (A-8) 参考文献:

  1. AAA+ 超家族 ATP 酶:结构相同,功能各异。  |  Ogura, T. and Wilkinson, AJ. 2001. Genes Cells. 6: 575-97. PMID: 11473577
  2. AAA ATP 酶 Cdc48/p97 及其伙伴将蛋白质从 ER 转运到细胞质中。  |  Ye, Y., et al. 2001. Nature. 414: 652-6. PMID: 11740563
  3. AAA+ ATPases 的进化史和高阶分类。  |  Iyer, LM., et al. 2004. J Struct Biol. 146: 11-31. PMID: 15037234
  4. 对 1 号染色体进化的新认识。  |  Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
  5. [AAA 蛋白超家族 ATP 酶的结构, 功能和作用机制]。  |  Kedzierska, S. 2006. Postepy Biochem. 52: 330-8. PMID: 17201069
  6. AAA+ 蛋白 ATAD3 具有位移环结合特性,参与线粒体核仁组织。  |  He, J., et al. 2007. J Cell Biol. 176: 141-6. PMID: 17210950
  7. ATAD 3A 和 ATAD 3B 是远端 1p 定位基因,在人类胶质瘤细胞系中表达不同,具有体外抗致癌和抗化疗特性。  |  Hubstenberger, A., et al. 2008. Exp Cell Res. 314: 2870-83. PMID: 18639545
  8. AAA 团队:具有不同功能的相关 ATP 酶。  |  Patel, S. and Latterich, M. 1998. Trends Cell Biol. 8: 65-71. PMID: 9695811
  9. AAA+:一类类似于伴侣的 ATP 酶,与蛋白质复合物的缔合, 运行和分解有关。  |  Neuwald, AF., et al. 1999. Genome Res. 9: 27-43. PMID: 9927482

订购信息

产品名称产品编号规格价格数量收藏夹

ATAD3B 抗体 (A-8)

sc-514615
200 µg/ml
RMB2377.00

ATAD3B (A-8) 中和勝肽

sc-514615 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-514615 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Good for Western blotAntibody works for Western blot with mouse cortical mitochondrial extracts; expression eliminated in ATAD3 KO mice in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Really strong antibody!Nice solid bands in Western blot, specific and reliable. Great choice!
Date published: 2017-01-19
Rated 2 out of 5 by from in WB, not good for meIn my Western blotting assay,detect quite a few unspecific bands, not good for me
Date published: 2017-01-19
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ATAD3B 抗体 (A-8) is rated 4.0 out of 5 by 3.
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