Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

Aquaporin 1/AQP1 抗体 (A-11): sc-55466

4.5(6)
寫評論提問
说明书
  • Aquaporin 1/AQP1抗体(A-11)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 免疫rat物种的AQP1的氨基酸249-269
  • 推荐用于 mouse, rat 和 human 来源的AQP1 WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 Aquaporin 1/AQP1 (B-11): sc-25287,可查看有标记的 Aquaporin 1/AQP1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是Aquaporin 1/AQP1 Antibody (A-11) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与Aquaporin 1/AQP1 Antibody (A-11) 打包提供(请参阅下面的订购信息)。
Gene Editing Promo Banner

快捷链接

関連項目

水通道蛋白(AQPs)是一大类结构性膜蛋白,可以促进水穿过细胞膜。这种功能在动物、植物和细菌中都得到保留。哺乳动物中已经鉴定出许多AQP异构体,分别称为AQP0至AQP10。AQPs分布广泛,同一细胞中存在多种AQP类型并不少见。尽管大多数AQP只对水有通透性,但AQP3、AQP7、AQP9和AQP10的两个转录本中的一个也对尿素和甘油有通透性。AQP2是唯一一种受到肾上腺素激活以增强肾小管吸收的水通道。AQPs参与肾脏水吸收、肺泡分泌、泪液分泌、脑脊液分泌和吸收以及眼液分泌和吸收。AQP1是一种在红细胞和肾小管细胞中表达的结构性膜蛋白。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Aquaporin 1/AQP1 抗体 (A-11) 参考文献:

  1. RNAi- 介导的 AQP1 表达沉默抑制了骨肉瘤细胞的增殖, 侵袭和肿瘤发生。  |  Wu, Z., et al. 2015. Cancer Biol Ther. 16: 1332-40. PMID: 26176849
  2. AQP1对恶性胸膜间皮瘤细胞粘附、迁移和肿瘤球形成的影响取决于基质和组织学类型。  |  Jagirdar, RM., et al. 2016. Am J Physiol Lung Cell Mol Physiol. 310: L489-95. PMID: 26773069
  3. 水通道蛋白AQP1在人类动脉粥样硬化血管病变中表达,AQP1缺乏会加剧血管紧张素II诱导的小鼠动脉粥样硬化。  |  Wintmo, P., et al. 2017. Acta Physiol (Oxf). 220: 446-460. PMID: 28129470
  4. 地塞米松通过上调AQP1对C6细胞增殖、迁移和侵袭的影响。  |  Guan, Y., et al. 2018. Oncol Lett. 15: 7595-7602. PMID: 29740485
  5. 特发性肺纤维化患者肺中AQP1的表达被修改:寻找可能的新靶点。  |  Galán-Cobo, A., et al. 2018. Front Mol Biosci. 5: 43. PMID: 29774214
  6. 心脏水通道蛋白对高渗压力的不同反应;AQP1 对诱导的细胞凋亡的有益作用。  |  Aggeli, IK., et al. 2021. Eur Rev Med Pharmacol Sci. 25: 313-325. PMID: 33506920
  7. 一个家族中的一组遗传性肺动脉高压病例,其三个兄弟姐妹均携带相同的新型 AQP1 c.273C>G 变异--病例报告。  |  Liang, KW., et al. 2023. Pulm Circ. 13: e12211. PMID: 37007933
  8. 慢病毒介导的RNA干扰靶向HMGB1,调节AQP1,以减轻慢性压迫背根神经节引起的疼痛。  |  Li, J., et al. 2024. Front Pharmacol. 15: 1469223. PMID: 39359252
  9. 缺氧通过 HIF1α 介导的肾 AQP1 上调减少小鼠尿量。  |  Qiao, R., et al. 2024. Kidney Dis (Basel). 10: 504-518. PMID: 39664329
  10. 红细胞白血病细胞中 Aqp1 的表达:糖皮质激素和化学诱导的遗传调控。  |  Moon, C., et al. 1997. Am J Physiol. 273: C1562-70. PMID: 9374641

订购信息

产品名称产品编号规格价格数量收藏夹

Aquaporin 1/AQP1 抗体 (A-11)

sc-55466
200 µg/ml
CNY2422.00

Aquaporin 1/AQP1 (A-11): m-IgG Fc BP-HRP 套装

sc-537038
200 µg Ab; 10 µg BP
CNY2715.00

Aquaporin 1/AQP1 (A-11): m-IgGκ BP-HRP 套装

sc-534222
200 µg Ab; 40 µg BP
CNY2715.00

Aquaporin 1/AQP1 (A-11): m-IgG1 BP-HRP 套装

sc-544972
200 µg Ab; 20 µg BP
CNY2715.00

Does this antibody can be used for the tissue  or cells in bovine? I need an AQP1 antibody can be reactive  in bovine aortic endothelia cells

Asked by: Shengwei Gan
Thank you for your question. Yes, the epitope for this antibody has a 100% sequence identity with bovine (accession#P47865), so it will pick up bovine samples that express AQP1. If you have any further questions, please contact Technical Service by phone, (800)-457-3801 option 2, email <[email protected]>, or by live chat directly on our website, www.scbt.com.
Answered by: Tech Service
Date published: 2017-03-01

I am using AQP1 (A-11): sc-55466 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: AbPolly
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_22, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_55466, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 96ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by PatriziLab from sehr gute ergebnise bei IF FärbungDer antikörper funktioniert sehr gut auf PFA Perfundiertem Maus gehirn.
Date published: 2022-06-21
Rated 5 out of 5 by Trav11 from Great for IHCThe AQP1 Antibody (A-11): sc-55466 provides great staining data for IHC studies when using formalin fixed, paraffin-embedded tissue sections, showing membrane and cytoplasmic localization.
Date published: 2017-01-27
Rated 5 out of 5 by CJ from Distinct band observed by Western Blot usingDistinct band observed by Western Blot using human kidney tissue extract. -SCBT QC
Date published: 2015-05-03
Rated 5 out of 5 by SF from Membrane and cytoplasmic staining of cellsMembrane and cytoplasmic staining of cells in glomeruli and cells in tubules by immunohistoperoxidase staining of formalinfixed, paraffin embedded human kidney tissue. -SCBT QC
Date published: 2015-03-18
Rated 4 out of 5 by FL from LargeLarge, slightly over-blown band observed by Western Blot using human kidney tissue extract. -SCBT QC
Date published: 2015-01-16
Rated 4 out of 5 by ET from Very strong bands observed by Western BlotVery strong bands observed by Western Blot using mouse and rat kidney tissue extracts. -SCBT QC
Date published: 2014-04-12
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_55466, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
Aquaporin 1/AQP1 抗体 (A-11) is rated 4.5 out of 5 by 6.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_55466, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 117ms
  • REVIEWS, PRODUCT