Date published: 2025-9-7

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APOBEC2 抗体 (B-12): sc-365151

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说明书
  • APOBEC2 抗体 B-12 是小鼠单克隆 IgG1 (kappa轻链),APOBEC2抗体,规格为200 µg/ml
  • 免疫human物种的代表全长APOBEC2的氨基酸1-224
  • APOBEC2 抗体 (B-12) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 APOBEC2; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 抗APOBEC2抗体(B-12)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取APOBEC2 (B-12): sc-365151免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是APOBEC2 Antibody (B-12) for WB applications. 的首选辅助检测试剂,这些试剂现与APOBEC2 Antibody (B-12) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    APOBEC2抗体(B-12)是一种IgG1 κ小鼠单克隆APOBEC2抗体(也被称为APOBEC2抗体),可通过WB、IP、IF和ELISA检测法检测来自小鼠、大鼠和人类的APOBEC2蛋白。APOBEC2抗体(B-12)有非偶联抗APOBEC2抗体形式和多种偶联抗APOBEC2抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。载脂蛋白B mRNA编辑酶、催化多肽样2(APOBEC2)是一种由224个氨基酸组成的蛋白质,属于胞苷和脱氧胞苷脱氨酶家族。APOBEC2仅在心脏和骨骼肌中表达,被认为是一种可能的C(胞嘧啶)到U(尿嘧啶)编辑酶。然而,与家族中的其他成员(如介导载脂蛋白(apo)B mRNA编辑的APOBEC1)不同,APOBEC2未显示出任何可检测的apoB mRNA编辑活性。此外,已证实APOBEC2具有低但明确的内在胞苷脱氨酶活性。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    APOBEC2 抗体 (B-12) 参考文献:

    1. 胞苷脱氨酶超基因家族中的心肌和骨骼肌特异性成员 APOBEC-2。  |  Liao, W., et al. 1999. Biochem Biophys Res Commun. 260: 398-404. PMID: 10403781
    2. 酵母 RNA 编辑脱氨酶的结构让我们深入了解了活化诱导脱氨酶和 APOBEC-1 的折叠和功能。  |  Xie, K., et al. 2004. Proc Natl Acad Sci U S A. 101: 8114-9. PMID: 15148397
    3. 多核苷酸(脱氧)胞苷脱氨酶 AID/APOBEC 家族的进化。  |  Conticello, SG., et al. 2005. Mol Biol Evol. 22: 367-77. PMID: 15496550
    4. 胞苷脱氨与抗逆转录病毒感染:从结构上理解 APOBEC 蛋白。  |  Huthoff, H. and Malim, MH. 2005. Virology. 334: 147-53. PMID: 15780864
    5. 缺乏 APOBEC2 和 APOBEC3 的小鼠。  |  Mikl, MC., et al. 2005. Mol Cell Biol. 25: 7270-7. PMID: 16055735
    6. 胞苷脱氨酶概述。  |  Navaratnam, N. and Sarwar, R. 2006. Int J Hematol. 83: 195-200. PMID: 16720547
    7. APOBEC-2 晶体结构及其对脱氨酶 AID 的功能影响。  |  Prochnow, C., et al. 2007. Nature. 445: 447-51. PMID: 17187054
    8. 免疫中的 DNA 脱氨基作用:AID 与其 APOBEC 亲缘关系。  |  Conticello, SG., et al. 2007. Adv Immunol. 94: 37-73. PMID: 17560271
    9. APOBEC2是溶液中的单体:对APOBEC3G模型的影响。  |  Krzysiak, TC., et al. 2012. Biochemistry. 51: 2008-17. PMID: 22339232
    10. APOBEC2 负向调节肌肉再生过程中的成肌细胞分化。  |  Ohtsubo, H., et al. 2017. Int J Biochem Cell Biol. 85: 91-101. PMID: 28215905
    11. Apobec2缺陷导致骨骼肌线粒体缺陷和线粒体自噬。  |  Sato, Y., et al. 2018. FASEB J. 32: 1428-1439. PMID: 29127187
    12. APOBEC2通过在成肌细胞分化过程中结合染色质并调节非肌肉基因的转录来保护骨骼肌细胞的命运。  |  Lorenzo, JP., et al. 2024. Proc Natl Acad Sci U S A. 121: e2312330121. PMID: 38625936

    订购信息

    产品名称产品编号规格价格数量收藏夹

    APOBEC2 抗体 (B-12)

    sc-365151
    200 µg/ml
    RMB2377.00

    APOBEC2 (B-12): m-IgG Fc BP-HRP 套装

    sc-527336
    200 µg Ab; 10 µg BP
    RMB2662.00

    APOBEC2 (B-12): m-IgG1 BP-HRP 套装

    sc-532709
    200 µg Ab; 20 µg BP
    RMB2662.00

    APOBEC2 抗体 (B-12) AC

    sc-365151 AC
    500 µg/ml, 25% agarose
    RMB3129.00

    APOBEC2 抗体 (B-12) HRP

    sc-365151 HRP
    200 µg/ml
    RMB2377.00

    APOBEC2 抗体 (B-12) FITC

    sc-365151 FITC
    200 µg/ml
    RMB2482.00

    APOBEC2 抗体 (B-12) PE

    sc-365151 PE
    200 µg/ml
    RMB2580.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 488

    sc-365151 AF488
    200 µg/ml
    RMB2685.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 546

    sc-365151 AF546
    200 µg/ml
    RMB2685.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 594

    sc-365151 AF594
    200 µg/ml
    RMB2685.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 647

    sc-365151 AF647
    200 µg/ml
    RMB2685.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 680

    sc-365151 AF680
    200 µg/ml
    RMB2685.00

    APOBEC2 抗体 (B-12) Alexa Fluor® 790

    sc-365151 AF790
    200 µg/ml
    RMB2685.00

    I am interested in the APOBEC2 antibody. Is it possible for you to give me an aliquot of the Sol8 cell extract?

    Asked by: Navnav
    Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
    Answered by: Technical Support
    Date published: 2021-07-22

    Hi, Can I get a free testing sample for APOBEC2 Antibody (B-12): sc-365151? Let me know if you can.

    Asked by: NickJun
    Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody.
    Answered by: Technical Support
    Date published: 2019-02-27

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with APOBEC2 (B-12): sc-365151?

    Asked by: DefinitelyNotMatt
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Nice Western Blot data of APOBEC2 expressionNice Western Blot data of APOBEC2 expression in Sol8 whole cell lysate. -SCBT QC
    Date published: 2015-03-10
    Rated 5 out of 5 by from Good Western Blot data of APOBEC2 expressionGood Western Blot data of APOBEC2 expression in mouse skeletal muscle tissue extract. -SCBT QC
    Date published: 2014-03-31
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    APOBEC2 抗体 (B-12) is rated 5.0 out of 5 by 2.
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