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Annexin-2/ANXA2 抗体 (H-3): sc-271175

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说明书
  • Annexin-2/ANXA2抗体(H-3)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 与human起源的Annexin II的N-terminus附近的肽图谱
  • 推荐用于 mouse, rat 和 human 来源的Annexin II WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 看 Annexin-2/ANXA2 (C-10): sc-28385,可查看有标记的 Annexin-2/ANXA2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是Annexin-2/ANXA2 Antibody (H-3) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与Annexin-2/ANXA2 Antibody (H-3) 打包提供(请参阅下面的订购信息)。
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    関連項目

    膜联蛋白家族(annexin family)的钙结合蛋白至少由十个哺乳动物基因组成,其特点是具有一个保守的核心结构域,该结构域以Ca2+依赖的方式与磷脂结合,以及一个独特的氨基末端区域,可能赋予结合特异性。这些蛋白质与生物膜之间的相互作用导致了一个假设,即它们参与细胞转运过程,如内吞作用、外排作用和细胞粘附。膜联蛋白I,也被称为脂皮质素,已被牵涉为糖皮质激素产生的抗炎反应的介质,以及cPLA2(一种强效的炎症介质)的抑制剂。膜联蛋白II,也被称为p36,以单体形式或作为与S-100相关蛋白p11形成的异四聚体存在。这种复合物被称为calpactin I。在四聚体形式中,膜联蛋白II是PKC家族和Src pp60的有效底物。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Annexin-2/ANXA2 抗体 (H-3) 参考文献:

    1. Annexin II轻链调节感觉神经元特异性钠通道的表达。  |  Okuse, K., et al. 2002. Nature. 417: 653-6. PMID: 12050667
    2. 肺泡 II 型细胞中 Annexin A2 与 Rab14 的相互作用  |  Gou, D., et al. 2008. J Biol Chem. 283: 13156-64. PMID: 18332131
    3. 附件蛋白II整合到流感病毒颗粒中,通过将纤溶酶原转化为纤溶酶来支持病毒复制。  |  LeBouder, F., et al. 2008. J Virol. 82: 6820-8. PMID: 18448517
    4. Annexin II与肠病毒71的衣壳蛋白VP1结合,增强病毒感染性。  |  Yang, SL., et al. 2011. J Virol. 85: 11809-20. PMID: 21900167
    5. Annexin II参与抵抗紫外线B诱发的细胞死亡,并增强人体细胞中紫外线损伤DNA的核苷酸切除修复能力。  |  Yano, A., et al. 2013. Biosci Biotechnol Biochem. 77: 307-11. PMID: 23391921
    6. Annexin A2系统与血管生成。  |  Liu, W. and Hajjar, KA. 2016. Biol Chem. 397: 1005-16. PMID: 27366903
    7. Annexin A2对病毒生命周期的影响。  |  Park, IW., et al. 2024. Virus Res. 345: 199384. PMID: 38702018
    8. Annexin II的表达在哺乳动物细胞周期中受到调控。  |  Chiang, Y., et al. 1993. Cancer Res. 53: 6017-21. PMID: 8261416
    9. Annexin II 通过翻译后机制上调细胞中 p11 蛋白的水平。  |  Puisieux, A., et al. 1996. Biochem J. 313 (Pt 1): 51-5. PMID: 8546709
    10. 人类B细胞淋巴瘤细胞系中Annexin II的表达改变。  |  Chiang, Y., et al. 1996. Biochim Biophys Acta. 1313: 295-301. PMID: 8898868

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Annexin-2/ANXA2 抗体 (H-3)

    sc-271175
    200 µg/ml
    CNY2422.00

    Annexin-2/ANXA2 (H-3): m-IgG Fc BP-HRP 套装

    sc-537580
    200 µg Ab; 10 µg BP
    CNY2715.00

    Annexin-2/ANXA2 (H-3): m-IgGκ BP-HRP 套装

    sc-534885
    200 µg Ab; 40 µg BP
    CNY2715.00

    Annexin-2/ANXA2 (H-3): m-IgG1 BP-HRP 套装

    sc-545242
    200 µg Ab; 20 µg BP
    CNY2715.00

    Annexin-2/ANXA2 (H-3) 中和勝肽

    sc-271175 P
    100 µg/0.5 ml
    CNY519.00

    What application is the blocking peptide sc-271175 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-24
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    Rated 5 out of 5 by SM from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the mouse Annexin II protein via Western Blot analysis. -SCBT QC
    Date published: 2015-04-07
    Rated 5 out of 5 by NZ from Bold band observed at expected molecularBold band observed at expected molecular weight using product sc-271175 with HeLa cells in WB analysis. -SCBT QC
    Date published: 2015-03-17
    Rated 5 out of 5 by ET from Excellent immunoperoxidase membrane and cytoplasmicExcellent immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
    Date published: 2015-02-04
    Rated 5 out of 5 by SS from Positive detection of endogenous AnnexinPositive detection of endogenous Annexin II protein in NIH/3T3 and KNRK whole cell lysates. -SCBT QC
    Date published: 2015-02-03
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    Annexin-2/ANXA2 抗体 (H-3) is rated 5.0 out of 5 by 4.
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