Date published: 2025-9-7

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alpha Synuclein 抗体 (3H2897): sc-69977

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说明书
  • alpha Synuclein 抗体 3H2897 是小鼠单克隆 IgG1, 在38篇文献中引用,提供 50 µg/500 µl
  • 免疫human物种的重组α-synuclein
  • 推荐用于 mouse, rat 和 human 来源的α-synuclein WB, IP, IF 和 IHC(P)检测
  • 看 alpha Synuclein (211): sc-12767,可查看有标记的 alpha Synuclein 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 关于如何获取alpha Synuclein (3H2897): sc-69977免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 alpha Synuclein 抗体 (3H2897) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与alpha Synuclein 抗体 (3H2897) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

α-synuclein抗体(3H2897)是一种小鼠单克隆IgG1 kappa轻链抗体,用于通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和石蜡包埋切片免疫组织化学(IHCP)技术检测小鼠、大鼠和人类样本中的α-synuclein(又称SNCA或NACP)。α-突触核蛋白单克隆抗体(3H2897)可识别人类来源的重组α-突触核蛋白,有助于研究该蛋白的各种翻译后修饰,这对于理解其在疾病中的功能和作用至关重要。α-突触核蛋白主要在脑部表达,特别是在神经元细胞体和突触内,α-突触核蛋白在突触囊泡运输和神经递质释放中发挥着至关重要的作用,而神经递质释放是神经元有效沟通和可塑性的必要过程。α-突触核蛋白的翻译后修饰,如磷酸化、泛素化和硝化,会显著影响其结构构象和聚集倾向。这些修饰非常重要,因为它们会改变正常功能并促进病理聚集的形成,包括路易体,这是帕金森病的特征,也与阿尔茨海默病有关。了解这些修饰有助于阐明突触核蛋白病的基础机制,并促进开发有针对性的治疗策略,以预防或减少聚集。α-突触核蛋白(3H2897)抗体以未结合形式提供,为各种实验应用提供了灵活性。α-突触核蛋白单克隆抗体(3H2897)是推进α-突触核蛋白在维持神经元健康和参与致残性神经退行性疾病发病机理方面研究的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

alpha Synuclein 抗体 (3H2897)

sc-69977
50 µg/500 µl
RMB2377.00

alpha Synuclein (3H2897): m-IgG Fc BP-HRP 套装

sc-539260
50 µg Ab; 10 µg BP
RMB2662.00

alpha Synuclein (3H2897): m-IgG1 BP-HRP 套装

sc-541360
50 µg; 20 µg BP
RMB2662.00

What is the epitope of this antibody?

Asked by: MFAltay
Thank you for your question. This antibody, sc-69977 α-synuclein (3H2897), was raised against recombinant α-synuclein of human origin. The exact epitope has not been mapped.
Answered by: Tech Service
Date published: 2019-09-17

Is α-synuclein Antibody (3H2897): sc-69977 available directly conjugated to HRP or fluorescent dyes?

Asked by: jenni
Thank you for your question. All requests for directly conjugated versions of this antibody should be directed to our Special Orders team at [email protected] Alternatively, consider using α-synuclein (211), which is available conjugated to HRP, FITC, PE, Alexa Fluor® 488 and Alexa Fluor® 647. (https://www.scbt.com/scbt/product/alpha-synuclein-antibody-211)
Answered by: Technical Support 3
Date published: 2017-01-09
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Rated 4 out of 5 by from Good for WBTested in western blot 1:500 on human lysates. Strong band with medium background. Recommended
Date published: 2023-12-13
Rated 5 out of 5 by from Good western blot signalsAt 2µg, good signals with low backgound in western blot
Date published: 2019-08-30
Rated 5 out of 5 by from good for IHCcytoplasmic staining, positive in control cells and negative in α-synuclein KO cells
Date published: 2018-02-13
Rated 1 out of 5 by from Didn't work for our application IHCThis antibody didn't work for our application IHC 1:250. Tested several times with diferent concentrations.
Date published: 2017-12-07
Rated 5 out of 5 by from Good alpha-synuclein antibodyGood antibody for alpha-synuclein detection of mouse, rat, and human samples. Strong bands observed in WB.
Date published: 2017-01-20
Rated 4 out of 5 by from Nice productVery nice western blot data; strong signal with low background
Date published: 2017-01-09
Rated 4 out of 5 by from Function is goodthe sensitivity specificity is good, We'll buy it again
Date published: 2016-11-14
Rated 4 out of 5 by from WB: Strong band detected in human alpha synucleinWB: Strong band detected in human alpha synuclein transfected lysates.
Date published: 2015-03-31
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alpha Synuclein抗体 (3H2897) is rated 4.0 out of 5 by 10.
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