Date published: 2026-10-24

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ABCG2 Antibody (B-1) - Immunohistochemistry - Image 293361
ABCG2 抗体 (B-1): sc-377176. 福尔马林固定, 石蜡包埋的人胆囊组织的免疫过氧化物酶染色, 显示腺细胞膜和胞质染色.
ABCG2 Antibody (B-1) - Immunohistochemistry - Image 293361
ABCG2 抗体 (B-1): sc-377176. 福尔马林固定, 石蜡包埋的人胆囊组织的免疫过氧化物酶染色, 显示腺细胞膜和胞质染色.
ABCG2 Antibody (B-1) - Western Blotting - Image 281877
ABCG2 抗体 (B-1): sc-377176. 未转染 293T: sc-117752 (A), 人 ABCG2 转染 293T: sc-172393 (B) 和 HL-60/MX1 (C) 全细胞裂解液中 ABCG2 表达的 Western 印迹分析.
ABCG2 Antibody (B-1) - Western Blotting - Image 374303
ABCG2 抗体 (B-1): sc-377176. MCF7 全细胞裂解液中 ABCG2 表达的近红外 Western 印迹分析. 用 UltraCruz® 阻断试剂阻断: sc-516214. 所用检测试剂: m-IgGκ BP-CFL 680: sc-516180.
ABCG2 抗体 (B-1): sc-377176. 福尔马林固定, 石蜡包埋的人胆囊组织的免疫过氧化物酶染色, 显示腺细胞膜和胞质染色.

ABCG2 抗体 (B-1): sc-377176

4.8(13)
寫評論提問
说明书
  • ABCG2 抗体 B-1 是小鼠单克隆 IgG1 κ，ABCG2抗体, 在46篇文献中引用，规格为200 µg/ml
  • 免疫原氨基酸序列301-370位于human物种的ABCG2的内部区域内
  • ABCG2 抗体 (B-1) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 ABCG2
  • 抗ABCG2抗体（B-1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgGκ BP-HRP是ABCG2 Antibody (B-1) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现可与ABCG2 Antibody (B-1) 搭配使用（请参阅下面的订购信息）。有关其它 m-IgGκ BP 结合物，请参阅我们完整的小鼠 IgG 结合蛋白列表。
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描述
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说明书与实验方案
研究信息

関連項目

额外ABC抗体，包括ABCF1, ABCG2, ABCF2, ABCA6, ABCB9, ABCC13, ABCC11, ABCD3和ABCB5

ABCG2抗体（B-1）是一种IgG1κ小鼠单克隆ABCG2抗体（也称为CD338抗体或ATP结合盒亚家族G成员2抗体），可通过WB、IP、IF、IHC（P）和ELISA检测人源ABCG2蛋白。ABCG2抗体（B-1）既可作为非偶联的抗ABCG2抗体形式，也可作为多种偶联形式的抗ABCG2抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。ATP结合盒（ABC）转运蛋白是一个进化上保守的蛋白质家族，通过ATP水解的能量催化分子跨细胞外和细胞内膜的运输。ABC半转运蛋白ABCG2也被称为胎盘特异性ABC转运蛋白和乳腺癌症耐药性蛋白（BCRP1）。ABCG2对多种化疗药物具有抗性，包括蒽环类、米托蒽醌、比沙替尼和拓扑替康。在正常情况下，ABCG2可以通过清除细胞中的毒素发挥保护作用，并在调节干细胞分化中发挥重要作用。ABCG2负责侧群（SP）表型，并在多种干细胞中广泛表达，使其成为重要的干细胞标记。ABCG2可能具有N-连接的糖基化，并可能在体内二聚化。ABCG2在胎盘、肝脏、肠和干细胞中大量表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ABCG2 抗体 (B-1) 参考文献:

  1. 胎盘和胎儿中的ABCB1和ABCG2表达：种间比较。  |  Myllynen, P., et al. 2010. Expert Opin Drug Metab Toxicol. 6: 1385-98. PMID: 20738225
  2. ABCG2和ABCB6在卟啉代谢和细胞存活中的作用。  |  Krishnamurthy, P. and Schuetz, JD. 2011. Curr Pharm Biotechnol. 12: 647-55. PMID: 21118089
  3. KO143（一种ABCG2抑制剂）的代谢。  |  Liu, K., et al. 2017. Drug Metab Pharmacokinet. 32: 193-200. PMID: 28619281
  4. ABCG2（BCRP）在人类疾病和药物反应中的逆向转化研究。  |  Brackman, DJ. and Giacomini, KM. 2018. Clin Pharmacol Ther. 103: 233-242. PMID: 29023674
  5. Abcg2转运蛋白影响血浆、乳汁和组织中的美洛昔康水平。  |  Garcia-Lino, AM., et al. 2020. Biochem Pharmacol. 175: 113924. PMID: 32217099
  6. ABCG2的过表达会导致对泛素激活酶（UAE）抑制剂MLN7243产生抗性。  |  Wu, ZX., et al. 2021. Front Cell Dev Biol. 9: 697927. PMID: 34336849
  7. ABCG2基因多态性对牛皮癣易感性的影响。  |  Huang, YH., et al. 2021. Genes (Basel). 12: PMID: 34680995
  8. 核苷酸结合是 ABCG2 构象转变的关键调节因子。  |  Gyöngy, Z., et al. 2023. Elife. 12: PMID: 36763413
  9. ABCG2基因和ABCG2蛋白在结直肠癌中的表达--硅学和湿分析。  |  Sałagacka-Kubiak, A., et al. 2023. Int J Mol Sci. 24: PMID: 37445716
  10. ABCG2表达作为人类胶质瘤的潜在生存预测因子。  |  Raguž, M., et al. 2024. Int J Mol Sci. 25: PMID: 38542090

订购信息

产品名称产品编号规格价格数量收藏夹

ABCG2 抗体 (B-1)

sc-377176
200 µg/ml
CNY2422.00

ABCG2 (B-1): m-IgGκ BP-HRP 套装

sc-523225
200 µg Ab, 40 µg BP
CNY2715.00

ABCG2 抗体 (B-1) AC

sc-377176 AC
500 µg/ml, 25% agarose
CNY3189.00

ABCG2 抗体 (B-1) HRP

sc-377176 HRP
200 µg/ml
CNY2422.00

ABCG2 抗体 (B-1) FITC

sc-377176 FITC
200 µg/ml
CNY2527.00

ABCG2 抗体 (B-1) PE

sc-377176 PE
200 µg/ml
CNY2625.00

ABCG2 抗体 (B-1) Alexa Fluor® 488

sc-377176 AF488
200 µg/ml
CNY2738.00

ABCG2 抗体 (B-1) Alexa Fluor® 546

sc-377176 AF546
200 µg/ml
CNY2738.00

ABCG2 抗体 (B-1) Alexa Fluor® 594

sc-377176 AF594
200 µg/ml
CNY2738.00

ABCG2 抗体 (B-1) Alexa Fluor® 647

sc-377176 AF647
200 µg/ml
CNY2738.00

ABCG2 抗体 (B-1) Alexa Fluor® 680

sc-377176 AF680
200 µg/ml
CNY2738.00

ABCG2 抗体 (B-1) Alexa Fluor® 790

sc-377176 AF790
200 µg/ml
CNY2738.00

What is the preferred secondary antibody to use in immunostaining?

Asked by: Maria
Thank you for your question. https://www.scbt.com/p/mouse-igg1-binding-protein-cruzfluor-488
Answered by: BlakeJ
Date published: 2025-04-04

What is the best secondary to use with this antibody?

Asked by: AbPolly
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 15
Date published: 2017-01-26
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Rated 5 out of 5 by Mariakras from ABCG2 antibody (B1)We got very nice western blot images using this antibody. It correlated well with the expression of the ABCG2 based on RT PCR
Date published: 2026-07-08
Rated 5 out of 5 by Leonid from Good!Good western blot result for human placenta (50ug),antibody diluted at 1 :100
Date published: 2018-03-09
Rated 4 out of 5 by fornafra from The antibody worked properly in WBA specific band of correct molecular weight was seen in all my samples. I am satisfied of my results
Date published: 2017-08-28
Rated 5 out of 5 by CPUXie from Good antibodyVery good antibody for Western blotting I have used the antibody as per recommended dilution (1:200) for western blotting. It gives strong bands at correct length. Good antibody for western blotting.
Date published: 2017-08-03
Rated 5 out of 5 by Zurcaled from Worked wonderfully well!Works well for human tissue, tested on Human Liver using citrate buffer, Leica post primary and polymer, with DAB developing!
Date published: 2017-06-27
Rated 5 out of 5 by cgd_san from Great western blotGreat western blot result for human breast cancer cells,antibody diluted at 1 :400.
Date published: 2017-05-28
Rated 4 out of 5 by kuaixingwang from goodWestern Blot ,human gastric carcinoma BGC823,1:200 for3 hours,I get a clear result
Date published: 2017-02-22
Rated 5 out of 5 by Professor Griffin from Great stainVery nice stain by IHC (P) with ABCG2 Antibody (B-1)
Date published: 2017-01-19
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ABCG2 抗体 (B-1) is rated 4.8 out of 5 by 13.
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