Date published: 2026-2-2

1-800-457-3801

SCBT Portrait Logo
Seach Input

ABCG2 抗体 (BXP-53): sc-58224

5.0(6)
寫評論提問

说明书
  • ABCG2 抗体 BXP-53 是大鼠单克隆 IgG2a, 在24篇文献中引用,提供 50 µg/0.5 ml
  • 免疫mouse物种的ABCG2的氨基酸221-394
  • 推荐用于 mouse, rat 和 human 来源的ABCG2 WB, IP, IF 和 FCM检测
  • 看 ABCG2 (B-1): sc-377176,可查看有标记的 ABCG2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成ABCG2 抗体 (BXP-53)的首选二抗检测试剂的鉴定。这项工作正在进行中。
Crispr Promo Banner

快捷链接

関連項目

ABCG2 抗体(BXP-53)是大鼠单克隆 IgG2a 抗体,可通过免疫印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和流式细胞术(FCM)检测小鼠、大鼠和人类样本中的 ABCG2。抗 ABCG2 抗体 (BXP-53) 以非结合形式提供,为研究人员提供了研究这种关键蛋白的多功能工具。ABCG2 又称胎盘特异性 ABC 转运体和乳腺癌抗性蛋白 (BCRP1),在利用 ATP 水解产生的能量跨细胞膜转运各种分子方面起着至关重要的作用。ABCG2 尤其重要,因为它参与了一系列化疗药物(包括蒽环类和托泊替康)耐药性的产生,这给癌症治疗带来了挑战。ABCG2对维持干细胞的侧群(SP)表型至关重要,突出了其作为干细胞标记物的重要性。ABCG2主要在胎盘、肝脏、肠道和各种干细胞中表达,ABCG2可能通过将毒素排出细胞和调节干细胞分化发挥保护功能。值得注意的是,ABCG2 可能会进行 N-连接的糖基化,并有可能在体内二聚化,这可能会影响其功能特性以及与其他蛋白质的相互作用。ABCG2 的这种多方面作用强调了它在正常生理和疾病状态中的重要意义,使 ABCG2 (BXP-53) 抗体成为研究人员调查各种功能和治疗抗性影响的必备试剂。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

ABCG2 抗体 (BXP-53)

sc-58224
50 µg/0.5 ml
RMB2422.00

Which secondary anti-body will be appropriate for BXP-53? also, does antibodies for mouse-IgG k work as a secondary antibody?

Asked by: Toshi_1993
ABCG2 Antibody (BXP-53) is a rat monoclonal IgG2a. We would recommend using a secondary antibody that is anti-rat IgG2a for detection of this primary antibody. Unfortunately, we do not currently anti-rat IgG secondaries available at this time. Our mouse IgG kappa binding protein will not work as a secondary antibody for detection of rat IgG.
Answered by: Technical Support
Date published: 2018-11-14

I would like to use ABCG2 Antibody (BXP-53): sc-58224 for double staining with another mouse monoclonal primary antibody. Is this possible?

Asked by: Trav11
Thank you for your question. In cases like this, we recommend using our directly conjugated mouse monoclonal primary antibodies. Currently, sc-58224 is not available directly conjugated, but we have an alternative HNF-3α antibody (sc-377176) that is available conjugated to HRP, FITC, PE, Alexa Fluor® 488 and Alexa Fluor® 647. If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Technical Support 5
Date published: 2017-02-04
  • y_2026, m_2, d_1, h_11CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_58224, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 102ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Extremely popular ABCG2 antibodyThe BXP-53 clone is extremely popular choice for detection of ABCG2 by Western blot.
Date published: 2017-01-13
Rated 5 out of 5 by from Reported to be suitable for use in WB usingReported to be suitable for use in WB using mouse spinal cord, cerebral cortex and cerebellum tissue. -SCBT Publication Review
Date published: 2015-04-23
Rated 5 out of 5 by from WB Published with this antibody immunoblotWB Published with this antibody immunoblot analysis using chicken kidney(proximal tubule) tissue. -SCBT Publication Review
Date published: 2015-04-07
Rated 5 out of 5 by from WB positive with human P5 HCC and IGROV1;WB positive with human P5 HCC and IGROV1; Also in canine - MDCKII and MDCK-BCRP cells. -SCBT Publication Review
Date published: 2015-03-12
Rated 5 out of 5 by from Good IF data with human P5 HCC and IGROV1;Good IF data with human P5 HCC and IGROV1; Also in canine - MDCKII and MDCK-BCRP cells. -SCBT Publication Review
Date published: 2015-03-10
Rated 5 out of 5 by from Good signal strength observed in WB using HLGood signal strength observed in WB using HL-60/MX-1, JAR and MCF-7 whole cell lysates. -SCBT QC
Date published: 2013-11-21
  • y_2026, m_2, d_1, h_11
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_58224, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
ABCG2 抗体 (BXP-53) is rated 5.0 out of 5 by 6.
  • y_2026, m_2, d_1, h_11
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_58224, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 95ms
  • REVIEWS, PRODUCT