Placental lactogen I inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of placental lactogen I (PL-I). PL-I is a hormone produced by the placenta during pregnancy and is involved in regulating maternal metabolism and fetal growth. Inhibition of PL-I aims to disrupt its actions and potentially modulate the effects it exerts on maternal physiology and fetal development. The chemical structures of PL-I inhibitors can vary, including compounds that interfere with PL-I signaling pathways, production, or its interactions with receptors.
Researchers have explored various strategies to target PL-I and attenuate its effects during pregnancy. The study of PL-I inhibitors provides valuable insights into the complex regulatory mechanisms governing maternal-fetal interactions and pregnancy physiology. Continued research in this chemical class holds promise for advancing our understanding of placental biology and its potential implications in various biological contexts.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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Bromocriptine | 25614-03-3 | sc-337602A sc-337602B sc-337602 | 10 mg 100 mg 1 g | ¥632.00 ¥2933.00 ¥6273.00 | 4 | |
多巴胺激动剂溴隐亭可通过激活多巴胺受体抑制胎盘泌乳素,多巴胺受体通过抑制性 G 蛋白发出信号,导致泌乳细胞中腺苷酸环化酶活性降低和 cAMP 水平下降。 | ||||||
Cabergoline | 81409-90-7 | sc-203864 sc-203864A | 10 mg 50 mg | ¥3385.00 ¥11903.00 | ||
卡麦角林的作用与溴隐亭类似,是一种对多巴胺D2受体具有高亲和力的多巴胺激动剂,通过降低泌乳细胞中的细胞内cAMP来抑制胎盘泌乳素。 | ||||||
Metergoline | 17692-51-2 | sc-204079 sc-204079A | 10 mg 50 mg | ¥880.00 ¥3227.00 | ||
Metergoline 是一种血清素和多巴胺受体拮抗剂,可通过阻断参与分泌胎盘泌乳素的多巴胺受体来抑制胎盘泌乳素。 | ||||||
Ritanserin | 87051-43-2 | sc-203681 sc-203681A | 10 mg 50 mg | ¥982.00 ¥3452.00 | 2 | |
Ritanserin是一种5-羟色胺受体拮抗剂,可通过干扰5-羟色胺受体来抑制胎盘泌乳素,从而间接调节与胎盘泌乳素分泌有关的多巴胺通路。 | ||||||
Pimozide | 2062-78-4 | sc-203662 | 100 mg | ¥1151.00 | 3 | |
匹莫齐特是一种多巴胺受体拮抗剂,可通过阻断调节泌乳细胞产生和分泌泌乳素的多巴胺受体来抑制胎盘泌乳素。 | ||||||
Domperidone | 57808-66-9 | sc-203032 sc-203032A | 50 mg 250 mg | ¥677.00 ¥3170.00 | 2 | |
多潘立酮是一种多巴胺受体拮抗剂,可通过靶向控制泌乳细胞分泌激素的多巴胺受体来抑制胎盘泌乳素。 | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | ¥677.00 ¥1218.00 | 21 | |
多巴胺拮抗剂氯丙嗪可通过阻断参与调节泌乳素分泌的多巴胺受体来抑制胎盘泌乳素的释放。 | ||||||
Haloperidol | 52-86-8 | sc-507512 | 5 g | ¥2144.00 | ||
氟哌啶醇是一种强效多巴胺 D2 受体拮抗剂,可通过阻止多巴胺在泌乳细胞中的作用来抑制胎盘泌乳素,而多巴胺是分泌这种激素所必需的。 | ||||||
(RS)-(±)-Sulpiride | 15676-16-1 | sc-205494 | 100 mg | ¥778.00 | ||
舒必利是一种选择性多巴胺 D2 受体拮抗剂,可通过阻断多巴胺能对泌乳细胞的控制来抑制胎盘泌乳素,从而抑制激素的分泌。 | ||||||
Perphenazine | 58-39-9 | sc-208161 | 100 mg | ¥2144.00 | ||
哌苯那嗪是一种多巴胺受体拮抗剂,可通过拮抗调节泌乳激素分泌的多巴胺受体来抑制胎盘泌乳素。 |