FGF-8F inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the FGF-8F isoform, a member of the fibroblast growth factor (FGF) family. FGF-8F is one of several isoforms produced by alternative splicing of the FGF-8 gene, and it plays a crucial role in various biological processes, including embryonic development, cell growth, and differentiation. The FGF family is known for its involvement in complex signaling pathways that regulate cell behavior, and FGF-8F, in particular, has been implicated in the regulation of tissue development and the maintenance of certain cellular functions. By inhibiting FGF-8F, researchers can explore the specific roles this isoform plays in these processes, offering insights into its unique contributions compared to other FGF isoforms.
The use of FGF-8F inhibitors in scientific research allows for a detailed examination of the molecular mechanisms underlying FGF-8F's functions. By blocking its activity, scientists can observe the effects on cellular signaling pathways and identify the downstream targets and interactions that are influenced by FGF-8F. This approach helps to delineate the specific pathways through which FGF-8F exerts its effects, distinguishing it from other FGF family members and providing a clearer picture of its role in biological systems. Additionally, the study of FGF-8F inhibitors can contribute to a better understanding of how this isoform interacts with its receptors and other signaling molecules, shedding light on its involvement in various physiological processes. Overall, FGF-8F inhibitors are valuable tools for unraveling the complexities of FGF signaling and for advancing our knowledge of how specific isoforms contribute to the regulation of cellular and developmental processes.
関連項目
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | ¥519.00 ¥1579.00 ¥7672.00 | 16 | |
PD173074是一种强效且具有选择性的FGFR抑制剂,可直接靶向酪氨酸激酶结构域,阻止自磷酸化反应和下游信号传导。PD173074通过抑制FGFR,破坏FGF介导的信号通路,从而阻碍FGF调节的细胞过程,如增殖和血管生成。 | ||||||
SU 5402 | 215543-92-3 | sc-204308 sc-204308A | 1 mg 5 mg | ¥699.00 ¥1083.00 | 36 | |
SU5402是一种FGFR酪氨酸激酶活性的小分子抑制剂。它干扰FGFR的ATP结合位点,阻止自磷酸化反应和下游信号传导。SU5402通过直接抑制FGFR,破坏FGF介导的途径,影响与细胞生长、分化及血管生成相关的细胞反应。 | ||||||
AZD4547 | 1035270-39-3 | sc-364421 sc-364421A | 5 mg 10 mg | ¥2234.00 ¥3486.00 | 6 | |
AZD4547是一种选择性FGFR抑制剂,可抑制FGFR自磷酸化反应和下游信号传导。通过靶向激酶结构域,AZD4547直接抑制FGFR,破坏FGF介导的细胞过程,包括增殖和血管生成。这种化合物通过靶向FGFR信号通路,是调节FGF活性的特定方法。 | ||||||
BGJ398 | 872511-34-7 | sc-364430 sc-364430A sc-364430B sc-364430C | 5 mg 10 mg 50 mg 100 mg | ¥2392.00 ¥2787.00 ¥6566.00 ¥11158.00 | 4 | |
BGJ398是一种口服FGFR酪氨酸激酶抑制剂。通过与FGFR的ATP结合口袋结合,它可以阻止自磷酸化反应和下游信号传导。BGJ398直接抑制FGFR,破坏FGF介导的途径和与细胞增殖和血管生成相关的细胞反应。这种化合物通过抑制FGFR为调节FGF活性提供了靶向策略。 | ||||||
JNJ-26481585 | 875320-29-9 | sc-364515 sc-364515A | 5 mg 50 mg | ¥3622.00 ¥13809.00 | ||
JNJ-26481585是一种口服活性FGFR酪氨酸激酶抑制剂。通过与ATP结合位点结合,抑制自磷酸化反应和下游信号传导。JNJ-26481585直接作用于FGFR,阻断FGF介导的信号通路以及与细胞生长和血管生成相关的细胞反应。这种化合物通过抑制FGFR信号传导,为调节FGF活性提供了一种特殊方法。 |