Date published: 2025-10-10

021-6093-6350

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ANKRD18A 抑制因子

ANKRD18A inhibitors represent a specialized class of chemical compounds designed to modulate the activity of the ANKRD18A protein, which is involved in various cellular processes. This protein, characterized by the presence of ankyrin repeat domains, plays a crucial role in protein-protein interactions and the regulation of cellular signaling pathways. ANKRD18A inhibitors typically feature a diverse range of chemical structures, often comprising heterocyclic rings, aromatic systems, and specific functional groups that enhance binding affinity and selectivity for the target protein. The design of these inhibitors focuses on optimizing their interaction with the ANKRD18A protein, often employing techniques such as molecular docking and structure-activity relationship studies to identify optimal chemical scaffolds.

The approaches to creating ANKRD18A inhibitors often involve advanced chemistry methods, including multi-step synthesis and combinatorial chemistry. These inhibitors may exhibit varying degrees of potency and specificity, which are essential for understanding the biological roles of ANKRD18A in cellular contexts. Furthermore, the study of these compounds contributes to the broader understanding of cellular mechanisms by providing tools to dissect the functions of ANKRD18A. Research into this chemical class also involves examining the physicochemical properties of the compounds, such as solubility, stability, and permeability, to ensure their suitability for experimental applications. As a result, ANKRD18A inhibitors serve as valuable resources for researchers investigating the fundamental biology of the ANKRD18A protein and its involvement in various cellular processes.

関連項目

Items 1 to 10 of 12 total

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产品名称CAS #产品编号数量价格应用排名

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
¥824.00
¥2685.00
¥8089.00
¥28453.00
¥241660.00
53
(3)

这种抗生素会与 DNA 结合,抑制 RNA 聚合酶,从而可能减少 ANKRD18A mRNA 的合成。

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
¥451.00
¥925.00
¥2888.00
127
(5)

这种化合物通过阻断翻译过程中的转位来抑制蛋白质合成,从而可能降低 ANKRD18A 蛋白水平。

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
¥699.00
¥1749.00
¥3610.00
233
(4)

作为一种 mTOR 抑制剂,雷帕霉素会下调蛋白质合成途径,从而影响 ANKRD18A 的表达。

5-Azacytidine

320-67-2sc-221003
500 mg
¥3159.00
4
(1)

这种胞苷类似物会影响 DNA 甲基化,从而导致包括 ANKRD18A 在内的基因表达发生改变。

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
¥1681.00
¥5303.00
¥6995.00
¥13527.00
¥23579.00
33
(3)

通过抑制组蛋白去乙酰化酶,它可以影响染色质结构和基因表达,从而可能影响 ANKRD18A 的水平。

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
¥2933.00
¥11609.00
26
(2)

这种毒素会抑制 RNA 聚合酶 II,可能会减少 ANKRD18A 基因的转录物。

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
¥767.00
¥2945.00
8
(1)

它抑制单磷酸肌苷脱氢酶,影响核苷酸的合成,并可能减少 RNA 的合成,包括 ANKRD18A 的合成。

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
¥1094.00
¥2866.00
36
(2)

这种抗生素会抑制核糖体上肽键的形成,从而减少包括 ANKRD18A 在内的整个蛋白质合成。

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
¥643.00
¥2053.00
¥1038.00
21
(2)

它能抑制 DNA 复制和转录所必需的 DNA 拓扑异构酶 I,从而可能影响 ANKRD18A 的表达。

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
¥474.00
¥2087.00
¥3497.00
¥7333.00
6
(1)

这种化合物可选择性地抑制 RNA 聚合酶 II,从而导致 ANKRD18A 基因的转录物减少。