Date published: 2025-9-17

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Anticorps UDP-GlcDH (D-2): sc-137005

5.0(2)
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Fiches techniques
  • L'Anticorps UDP-GlcDH (D-2) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • soulevée contre les acides aminés 195-494 correspondant à C-terminus de UDP-GlcDH d'origine human.
  • recommandé pour la détection de UDP-glucose-6 dehydrogenase d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps UDP-GlcDH (D-2) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps UDP-GlcDH (D-2) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    UDP-GlcDH (also called UDP-glucose 6-dehydrogenase, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogenase family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluronan, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in signal transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first analyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGFβ and downregulated by hypoxia.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps UDP-GlcDH (D-2)

    sc-137005
    200 µg/ml
    RMB2377.00

    UDP-GlcDH (D-2): m-IgGκ BP-HRP Kit

    sc-534640
    200 µg Ab; 40 µg BP
    RMB2662.00

    UDP-GlcDH (D-2): m-IgG2b BP-HRP Kit

    sc-549274
    200 µg Ab; 10 µg BP
    RMB2662.00

    Can UDP-GlcDH (D-2): sc-137005 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: jerojero
    Thank you for your question. Yes, UDP-GlcDH (D-2): sc-137005 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-02-25
    • y_2025, m_9, d_17, h_8CST
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    Rated 5 de 5 de par Exceptional immunoperoxidase nuclear andExceptional immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human rectum tissue. -SCBT QC
    Date de publication: 2015-03-31
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    Anticorps UDP-GlcDH (D-2) est évalué 5.0 de 5 de 2.
    • y_2025, m_9, d_17, h_8
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    • REVIEWS, PRODUCT