Date published: 2025-9-16

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Anticorps TPO (A-6): sc-514326

5.0(1)
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Fiches techniques
  • L'Anticorps TPO (A-6) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 22-89 situés près de la région N-terminus de TPO d'origine mouse
  • recommandé pour la détection de TPO d'origine mouse par WB, IP, IF et ELISA
  • Le m-IgG Fc BP-HRP et le m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps TPO (A-6) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps TPO (A-6)(voir les informations relatives à la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Thrombopoietin (TPO or THPO), also known as c-Mpl ligand (c-Mpl L), is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production. TPO is expressed by both mature and progenitor megakaryocytes, as well as by human platelets. Human TPO cDNA encodes a 332 amino acid precursor with a 21 amino acid signal peptide which is cleaved to generate the mature protein. TPO isolated from serum ranges in molecular weight, which suggests that the protein is highly glycosylated. TPO exerts its biological effects through the TPO receptor, c-Mpl. Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, Tyk 2 and JAK2 which in turn phosphorylate Stat5 and Stat3, causing their nuclear translocation and the transcription of Stat responsive genes. The gene encoding TPO maps to human chromosome 3q26.3-q27.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps TPO (A-6)

    sc-514326
    200 µg/ml
    RMB2377.00

    TPO (A-6): m-IgG Fc BP-HRP Kit

    sc-538625
    200 µg Ab; 10 µg BP
    RMB2662.00

    TPO (A-6): m-IgGκ BP-HRP Kit

    sc-536271
    200 µg Ab; 40 µg BP
    RMB2662.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with TPO (A-6): sc-514326?

    Posée par: TinTin
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Répondue par: Technical Support
    Date de publication: 2017-02-27
    • y_2025, m_9, d_16, h_9CST
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    Rated 5 de 5 de par Nice Western blot data of mouse recombinant TPONice Western blot data of mouse recombinant TPO. -SCBT QC
    Date de publication: 2013-06-23
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    Anticorps TPO (A-6) est évalué 5.0 de 5 de 1.
    • y_2025, m_9, d_16, h_9
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