Anticorps O-GlcNAc transferase (A-6): sc-74547
- L'Anticorps O-GlcNAc transferase (A-6) est un monoclonal de souris IgG2a κ, cité dans 5 publications, fourni en 200 µg/ml
- soulevée contre les acides aminés 1-300 correspondant à N-terminus de O-GlcNAc transferase d'origine human.
- recommandé pour la détection de O-GlcNAc transferase d'origine mouse, rat et human par WB, IP, IF et ELISA; également réactif avec d'autres espèces, dont et equine, canine and bovine
- Voir O-GlcNAc transferase (F-12): sc-74546 pour d'autres anticorps conjugués O-GlcNAc transferase, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Le m-IgG Fc BP-HRP est le réactif de détection secondaire préféré pour l'anticorps O-GlcNAc transferase (A-6) pour les applications WB. Ce réactif est désormais proposé en bundle avec l'anticorps O-GlcNAc transferase (A-6)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
O-linked N-acetylglucosamine (O-GlcNAc) transferase (also designated OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. O-GlcNAc transferase has been purified from rat liver. It exists as a heterotrimeric complex with two subunits of the same molecular mass and one shorter subunit. Both polypeptides are related; the short subunit band is either a proteolytic product of the polypeptide or the product of an alternative translation start site. O-GlcNAc transferase is expressed as multiple transcripts that are present in different amounts in various human tissues, with the highest levels of expression in pancreas. Immunofluorescence of human cells expressing rat O-GlcNAc transferase indicated that it is present in both the nucleus and cytosol. HeLa cells expressing O-GlcNAc transferase do not survive well during prolonged incubations, suggesting that this protein may be toxic to the cells.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps O-GlcNAc transferase (A-6) | sc-74547 | 200 µg/ml | RMB2377.00 | |||
O-GlcNAc transferase (A-6): m-IgG Fc BP-HRP Kit | sc-539543 | 200 µg Ab; 10 µg BP | RMB2662.00 |