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Anticorps MetAP-1 (C-10): sc-376779

5.0(2)
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Fiches techniques
  • L'Anticorps MetAP-1 (C-10) est un monoclonal de souris IgM (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 359-382 au niveau C-terminus de MetAP-1 d'origine human
  • recommandé pour la détection de MetAP-1 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire MetAP-1 (C-10). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
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    Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. MetAP proetins remove the amino-terminal methionine residue from nascent polypeptides. MetAP-1 is a 394-amino acid protein that is expressed at low levels in all tissues, but is highly expressed in skeletal muscles. The active site of MetAP-1 contains two adjacent divalent metal ions connected by a water molecule or hydroxide ion. The control of cell proliferation in mammalian cells is directly linked and strictly dependent on the evolutionarily highly conserved mechanism that MetAP-1 employs. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. Pyridine-2-carboxylic acid thiazol-2-ylamide (PCAT) forms a scaffold that inhibits the action of MetAP-1, while 1,2,4-triazol is a non-peptide inhibitor of MetAP-1 binding to the active site with the N1 and N2 atoms of the triazole moiety complexing two divalent ions.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps MetAP-1 (C-10)

    sc-376779
    200 µg/ml
    CNY2422.00

    MetAP-1 (C-10) peptide neutralisant

    sc-376779 P
    100 µg/0.5 ml
    CNY519.00

    What application is the blocking peptide sc-376779 P appropriate for?

    Posée par: Germaine
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-25
    • y_2026, m_4, d_1, h_12CST
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    Rated 5 de 5 de par Beautiful immunoperoxidase cytoplasmic andBeautiful immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human uterine cervix tissue. -SCBT QC
    Date de publication: 2015-05-07
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    Anticorps MetAP-1 (C-10) est évalué 5.0 de 5 de 2.
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